PATTERNS OF ADVERSE DRUG REACTIONS: A STUDY IN A TERTIARY CARE HOSPITAL

Shakeel Ahmad Mir

doi:10.22159/ajpcr.2023.v16i12.48401

Authors

Shakeel Ahmad Mir Department of Clinical Pharmacology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.

DOI:

https://doi.org/10.22159/ajpcr.2023.v16i12.48401

Keywords:

Adverse drug reaction, Pharmacovigilance, Drug safety

Abstract

Objectives: The purpose of this study was to describe the pattern of adverse drug reactions (ADRs) in a tertiary care hospital, as ADRs are among the most common causes of morbidity and mortality.

Methods: This prospective study, which ran from January 2020 to December 2021, observed all patients admitted to the various departments of SKIMS Hospital Srinagar for the development of ADRs.

Results: ADRs were found to be slightly more prevalent in female patients (54.82%) and those aged 40–60 years (30.11%). Antibiotics (64.3%), anticancer drugs (9.4%), and gastrointestinal tract (GIT) medications (7.3%) were most commonly associated with ADRs. The commonly involved system organs were the skin (69.9%), the nervous system (24.1%), the GIT (19.5%), and the respiratory system (15.6%). 8.0% of ADRs were serious.

Conclusion: The prevalence of ADRs makes them a major concern. To ensure patient safety, active patient surveillance is critical to identifying and controlling ADRs.

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Author Biography

Shakeel Ahmad Mir, Department of Clinical Pharmacology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.

Associate Professor

Clinical Pharmacology

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