SERUM FERRITIN LEVELS AS A PROGNOSTIC INDICATOR IN ACUTE ISCHEMIC STROKE: A COMPREHENSIVE CLINICAL STUDY

Authors

  • Nasiba Khan Department of Medicine, SMS Medical College, Jaipur, Rajasthan, India.
  • Dharam Singh Meena Department of Medicine, SMS Medical College, Jaipur, Rajasthan, India.
  • Suraj Rajputohit Department of Medicine, SMS Medical College, Jaipur, Rajasthan, India.
  • Sudhir Bhandari Department of , Rajasthan University of Health Sciences, Jaipur, Rajasthan, India.

DOI:

https://doi.org/10.22159/ajpcr.2023.v16i10.49206

Keywords:

Serum ferritin, Acute ischemic stroke, Prognostic indicator, Stroke severity, Consciousness status, Disability outcomes

Abstract

Objective: This clinical study investigates the potential of serum ferritin levels as a prognostic indicator in acute ischemic stroke.

Methods: This cross-section study included 75 patients enrolled in our outpatient clinic, General Medicine Department, and SMS Medical College. The study enrolled all patients who had a new onset focal neurological deficit due to a stroke. A total of 75 patients (25 in each group (mild/moderate/ severe) as per the National Institute of Health Stroke Scale scoring) of >14 years old, presenting in the general medicine wards were enrolled for the study. The study assesses the correlation between serum ferritin levels and various clinical parameters, including stroke severity, consciousness status, and disability outcomes.

Results: Severe group had the highest average blood ferritin level (408.48 with a standard deviation (SD) of 68.63). A significant relationship was observed between ferritin levels and loss of consciousness. In addition, the mean ferritin residue ratio (MRS) also correlated with ferritin levels, with MRS correlating to ferritin levels. A significant association between elevated serum ferritin levels and severe stroke, as well as unfavorable outcomes.

Conclusion: The findings suggest that serum ferritin could serve as a promising prognostic index in acute ischemic stroke, aiding in patient risk stratification and clinical decision-making.

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Author Biographies

Nasiba Khan, Department of Medicine, SMS Medical College, Jaipur, Rajasthan, India.

Resident, Department of Medicine

Dharam Singh Meena, Department of Medicine, SMS Medical College, Jaipur, Rajasthan, India.

Resident, Department of Medicine

Suraj Rajputohit, Department of Medicine, SMS Medical College, Jaipur, Rajasthan, India.

Resident, Department of Medicine

Sudhir Bhandari, Department of , Rajasthan University of Health Sciences, Jaipur, Rajasthan, India.

Senior Professor and Vice Chancellor

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Published

07-10-2023

How to Cite

Khan, N., D. Singh Meena, S. Rajputohit, and S. Bhandari. “SERUM FERRITIN LEVELS AS A PROGNOSTIC INDICATOR IN ACUTE ISCHEMIC STROKE: A COMPREHENSIVE CLINICAL STUDY”. Asian Journal of Pharmaceutical and Clinical Research, vol. 16, no. 10, Oct. 2023, pp. 129-32, doi:10.22159/ajpcr.2023.v16i10.49206.

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