FUNCTIONAL OUTCOME OF PATIENTS WITH OSTEOARTHRITIS KNEE TREATED BY INTRAARTICULAR INJECTIONS OF PLATELET-RICH PLASMA

VIKAS KUNTWAD; PRAMOD PRALHAD TUPE; AMOL WAGH

doi:10.22159/ajpcr.2023.v16i11.49818

Authors

VIKAS KUNTWAD Department of Orthopaedics, IIMSR Medical College, Badnapur, Jalna, Maharashtra, India.
PRAMOD PRALHAD TUPE Department of Orthopaedics, IIMSR Medical College, Badnapur, Jalna, Maharashtra, India
AMOL WAGH Department of Orthopaedics, IIMSR Medical College, Badnapur, Jalna, Maharashtra, India.

DOI:

https://doi.org/10.22159/ajpcr.2023.v16i11.49818

Keywords:

Knee osteoarthritis, Intra-articular injection, Platelet-rich plasma, Functional outcome

Abstract

Objectives: The aims and objectives of the study are (1) to assess pain relief and functional outcome in knee osteoarthritis (OA) cases treated by intra-articular injection of platelet-rich plasma (PRP) and (2) to study the complication in patients treated by intra-articular injection of PRP.

Methods: This was a prospective study conducted in the department of orthopedics of a tertiary care medical institute. 60 patients with Grade 2 and Grade 3 OA of knee were included in this study on the basis of a pre-defined inclusion and exclusion criteria. All patients were treated by intra-articular injection of PRP. Patients were followed up for 6 months. During follow-up visits, assessment of severity of pain and functional outcome was done by Visual Analog Scale (VAS) Score and Japanese Orthopedic Association (JOA) Score. Patients were also assessed for complications. p<0.05 was taken as statistically significant.

Results: Out of 60 studied cases, there was a female preponderance with a M: F ratio of 1:0.62. The mean age of affected cases was found to be 65.84±11.86 years and mean duration of symptoms was found to be 2.52±1.26 years. Majority of the patients were either overweight (45.00%) or obese (36.67%) and only 11 (18.33%) patients had a healthy weight. 38 (63.33%) patients were having Grade 3 OA whereas 22 (36.67%) patients were having Grade 2 OA. There was a significant reduction in pain and significant functional improvement at the time of final follow-up as compared to VAS and JOA scores at the time of presentation (p<0.0001). Complications were seen in any of the cases.

Conclusion: Patients with Grade 2 and Grade 3 OA of knee treated by intra-articular injection of PRP show excellent outcome in terms of pain relief and functional outcome with no significant complications.

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