• Arcojit Ghosh department of pharmacology r g kar medical college kolkata
  • Asoke Kumar Das professor bankura sammilani medical college bankura
  • Prasanta K Gure
  • Sampurna Pati


CONTEXT: Majority of upper respiratory tract infections are caused by viruses & thus are self limiting. However, irrational prescription of drugs including antibiotics for URTI is a major problem worldwide. Thus, it is imperative to monitor drug utilization patterns from time to time in order to suitably modify prescribing patterns.

AIMS:  To evaluate the drug prescribing pattern in symptomatic upper respiratory tract infections in patients attending ENT OPD in R G Kar Medical College & Hospital, Kolkata.

SETTINGS & DESIGN: A prospective study based on a Medication Utilization Form, designed on the basis of WHO format.

METHODS & MATERIAL: The study was conducted in ENT OPD. The study population comprised of all patients with symptomatic URTI attending ENT OPD, RGKMCH. The data were obtained from the prescribing records.


RESULTS:  A total of 300 prescriptions were audited. It was found that 63.66% were males, 24.66% belonged to the age group of 26-35 yrs followed by 20.66% belonging to the age group of 16-25 yrs. The three most common URTIs diagnosed were otitis media(41%), pharyngitis (30%) & tonsillitis(12%). 594 drugs in total were prescribed to 300 patients (1.98 drugs per prescription). Among them 60% were generic prescriptions. Antibiotics were prescribed to 74% of patients. Average duration of treatment was 5-7 days. The most frequently prescribed antibiotic was amoxicillin & clavulinic acid (45%) followed by azithromycin (22%). Paracetamol accounted for majority of analgesic/ antipyretic prescriptions (57%). Antihistaminics were prescribed in 37% of cases. Nasal decongestants were prescribed to 14% patients & mucolytics to 7%.

CONCLUSION:  The study  revealed lesser utilization of antibiotics, better percentage of generic prescriptions &  duration of antibiotic therapy in comparison to similar studies.

Keywords: Upper respiratory tract infection, prescribing pattern, antibiotics.


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Author Biography

Arcojit Ghosh, department of pharmacology r g kar medical college kolkata

post graduate trainee

department of pharmacology
r g kar medical college
kolkataost graduate trainee


Jain N, Lodha R, Kabra SK. Upper respiratory tract infections. Indian J Pediatr.2001; 68:1135–8.

Needham A, Brown M, Freeborn S. Introduction and audit of general practice antibiotic formulary. J R Coll Gen Pract.1988; 38:166–7.

Huovinen P. Magic bullets, lost horizons: the rise and fall of antibiotics. BMJ.2002;324:176–9.

Laporte JR, Porta M, Capella D. Drug utilization studies: A tool for determining the effectiveness of drug use. Br J ClinPharmacol.1983;16:301–4.

Krishnaswamy K, Kumar BD, Radhaiah G. A drug delivery percept and practices.Eur J ClinPharmacol. 1985;29:363–70.

Laporte JR. Towards a healthy use of pharmaceuticals. Dev Dialogue. 1985;2:48–55.

Bharathiraja R, Sivakumar Sridharan, Luke Ravi Chelliah, Saradha Suresh and Mangayarkarasi Senguttuvan – Factors Affecting Antibiotic Prescribing Pattern In Pediatric Practice – Indian J Pediatr 2005;72 (10):877-879.

Shankar PR, Upadhyay DK, Subish P, Dubey AK, Mishra P. Prescribing patterns among pediatric inpatients in a teaching hospital in western Nepal. Singapore Med J. 2006;47:261–5.

Pradhan S, Jauhari AC. A study of antibiotics used in adult respiratory disorders in Kathmandu and Bhaktapur. Nepal Med Coll J. 2007;9:120–4.

Mazzaglia G, Greco S, Lando C, Cucinotta G, Caputi AP. Adult acute upper respiratory tract infections in Sicily: pattern of antibiotic drug prescription in primary care. J Antimicrob Chemother. 1998;41:259–66.

Nandimath MK, Ahuja S. Drug prescribing pattern in upper respiratory tract infection in children aged 1 – 14 years. International Journal of Pharma and Bio Sciences. 2012;3:299-308.

Atanasova I, Terziivanov D. Investigations on antibiotics in a hospital for 1 year period. Int J Clin Pharmacol Ther. 1995;33:32–3.

Till B, Williams L, Oliver SP, Pillans PI. A survey of inpatient antibiotic use in a teaching hospital. S Afr Med J. 1991;8:7–10.

Stille CJ, Andrade SE, Huang SS, Nordin J, Raebel MA, Go AS, et al. Increased use of second-generation macrolide antibiotics for children in nine health plans in the United States. Pediatrics. 2004;114:1206-11.

Ain MR, Shahzad N, Aqil M, Alam MS, Khanam R. Drug utilization pattern of antibacterials used in ear, nose and throat outpatient and inpatient departments of a university hospital at New Delhi, India. J Pharm Bioallied Sci. 2010 Jan-Mar; 2(1): 8–12.

Das BP, Sethi A, Rauniar GP, Sharma SK. Antimicrobial utilization pattern in out patient services of ENT department of tertiary care hospital of Eastern Nepal. Kathmandu Univ Med J (KUMJ) 2005;3:370–5.

Luks D, Anderson MR. Antihistamines and the common cold; a review and critic of the literature. J Gen Intern Med 1996;11:240-4.

Thomas M, Cherian AM, Mathai D. Measuring the impact of focused workshops on rational drug use. Trop Doct 1997;27:206-10.



How to Cite

Ghosh, A., A. K. Das, P. K Gure, and S. Pati. “AN OBSERVATIONAL STUDY OF DRUG USE IN UPPER RESPIRATORY TRACT INFECTION IN PATIENTS ATTENDING ENT OPD IN A TERTIARY CARE HOSPITAL IN KOLKATA”. Asian Journal of Pharmaceutical and Clinical Research, vol. 8, no. 4, July 2015, pp. 37-40,



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