A COMPARATIVE STUDY ON ORAL MUCOSAL LESIONS IN PATIENTS WITH DIABETES MELLITUS TYPE 2 AND HEALTHY SUBJECTS
DOI:
https://doi.org/10.22159/ajpcr.2024.v17i3.50831Keywords:
Diabetes mellitus, Oral mucosal lesions, Complications, PrevalenceAbstract
Objectives: The study was carried out to assess the prevalence of oral lesions in Type 2 Diabetes Mellitus (DM)patients and a control group comprising of non diabetic healthy patients. The findings of both groups were compared.
Methods: A total of 110 patients with Type-2 diabetes mellitus (Group A) and 110 healthy patients (Group B) were enrolled in this study. Oral examination was done to assess and compare the prevalence of oral mucosal lesions in both groups. All variables were described as relative and absolute values. Frequency distribution tables were made, mean and standard deviations were calculated. Categorical variables were measured as percentages, while continuous variables were expressed as mean±standard deviation.
Results: The male-to-female ratio of patients was 1:1.68 in Group A and 1:1.75 in Group B. The mean age was 52.68±11.42 years in Group A and 52.19±12.16 years in Group B. Majority of the patients (40.91%) reported a disease duration of 10–15 years. Oral lesions were more prevalent in the diabetic group 79.09% (n=87) than in the non-diabetic group (53.64%). The most common oral lesion was the coated tongue in the diabetic (71.81%) and the control group (40.91%).
Conclusion: The prevalence of oral mucosal lesions was found to be higher in the diabetic group in comparison to the control group.
Downloads
References
American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2010 Jan;33 Suppl 1:S62-9.
Banday MZ, Sameer AS, Nissar S. Pathophysiology of diabetes: An overview. Avicenna J Med. 2020 Oct 13;10(4):174-88.
Kumari S, Gnanasundaram N. Oral manifestations in diabetes mellitus-a review. J Indian Acad Oral Med Radiol. 2021;33(4):352-6.
Rohani B. Oral manifestations in patients with diabetes mellitus. World J Diabetes. 2019;10(9):485-9.
Al-Maskari AY, Al-Maskari MY, Al-Sudairy S. Oral manifestations and complications of diabetes mellitus: A review. Sultan Qaboos Univ Med J. 2011 May;11(2):179-86.
Shiferaw A, Alem G, Tsehay M, Kibret GD. Dental caries and associated factors among diabetic and nondiabetic adult patients attending Bichena Primary Hospital’s Outpatient Department. Front Oral Health. 2022 Nov 2;3:938405.
Singh IS, Singh A, Singh T, Kour R. Diabetes an inducing factor for dental caries: A case control analysis in Jammu. J Int Soc Prev Community Dent. 2016;6(2):125-9.
Petersen PE, Bourgeois D, Ogawa H, Estupinan-Day S, Ndiaye C. The global burden of oral diseases and risks to oral health. Bull World Health Organ. 2005;83(9):661-9.
Mohsin SF, Ahmed SA, Fawwad A, Basit A. Prevalence of oral mucosal alterations in type 2 diabetes mellitus patients attending a diabetic center. Pak J Med Sci. 2014;30(4):716-9.
Bastos AS, Leite AR, Spin-Neto R, Nassar PO, Massucato EM, Orrico SR. Diabetes mellitus and oral mucosa alterations: Prevalence and risk factors. Diabetes Res Clin Pract. 2011;92(1):100-5.
Al-Maweri SA, Ismail NM, Ismail AR, Al-Ghashm A. Prevalence of oral mucosal lesions in patients with type 2 diabetes attending hospital universiti sains malaysia. Malays J Med Sci. 2013;20(4):39-46.
Madathil J, Salim HP, Balan A, Radhakrishnan C, Kumar NR. Prevalence of oral lesions in patients with type 2 diabetes in north Kerala population. J Diabetol. 2020;11:32-8.
Neville B, Damm DD, Allen CM, Chi AC. Oral and Maxillo-Facial Pathology. Philadelphia, PA: WB Saunders; 1995. p. 11-2.
Silva MF, Barbosa KG, Pereira JV, Bento PM, Godoy GP, Gomes DQ. Prevalence of oral mucosal lesions among patients with diabetes mellitus types 1 and 2. An Bras Dermatol. 2015 Jan-Feb;90(1):49-53.
Bajaj S, Prasad S, Gupta A, Singh VB. Oral manifestations in type-2 diabetes and related complications. Indian J Endocrinol Metab. 2012;16:777-9.
Dikshit RP, Ramadas K, Hashibe M, Thomas G, Somanathan T, Sankaranarayanan R. Association between diabetes mellitus and pre-malignant oral diseases: A cross sectional study in Kerala, India. Int J Cancer. 2006;118:453-7.
Gong Y, Wei B, Yu L, Pan W. Type 2 diabetes mellitus and risk of oral cancer and precancerous lesions: A meta-analysis of observational studies. Oral Oncol. 2015;51:332-40.
Published
How to Cite
Issue
Section
Copyright (c) 2024 AMBRISH MISHRA, ANSHUMAN SHARMA, MEDHA SINGH TIWARI, DIVASHREE SHARMA
This work is licensed under a Creative Commons Attribution 4.0 International License.
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.
