FREE RADICAL SCAVENGING ACTIVITIES OF GARCINIA XANTHOCHYMUS HOOK. F. AND GARCINIA LANCEAEFOLIA ROXB. USING VARIOUS IN VITRO ASSAY MODELS.
Abstract
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Objective: The present research work has highlighted the free radical scavenging activities of methanolic pericarp extract of Garcinia xanthochymus
(MPEGX) and Garcinia lanceifolia (MPEGL) by using various in vitro assay models.
Methods: The present study was carried out by different methods such as 2,2/diphenyl-1-picrylhydrazine (DPPH), 2, 2'-azino-bis-3-
ethylbenzothiazoline-6-sulfonic acid (ABTS), Nitride oxide, and total iron reducing power. Further, total phenolic contents and total flavonoids
contents of the both crude extracts were also determined.
Result: The results revealed that MPEGX exhibited a high amount of phenolic contents and also showed the higher free radical scavenging activities in
ABTS, Nitride oxide, and total iron reducing power. Similarly, the MPEGL contained high amounts of flavonoids contents and exhibited higher activity
in DPPH model. From the result, it is suggested that the free radical scavenging activities of both the plant extract was directly co-related to both
phenolic and flavonoids contents.
Conclusion: Due to significant free radical activities of both plant extracts, it is justified that these plants have a significant amount of total antioxidant
compounds which has tremendous therapeutic potential.
Keywords: Antioxidant, Free radical scavenging, Garcinia xanthochymus, Garcinia lanceifolia, Pericarp.
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