ANTIBIOTIC SENSITIVITY OF GOLD AND SILVER NANOPARTICLES AGAINST ENTEROCOCCAL PATHOGENS

Authors

  • Hamzah Basil Mohammed Centre for Research & Post graduate studies, Indian Academy Degree College
  • R. Senthil Kumar

Abstract

Although disinfection methods currently used in drinking water treatment can effectively control microbial pathogens, research in the past few decades have revealed a dilemma between effective disinfection and formation of harmful and to consider innovative approaches that enhance the effectiveness. With the rapid advancement of nanoscience and nanotechnology, detailed knowledge of interactions between engineered nanomaterials and cells, tissues and organisms has become increasingly important, especially in regard to possible hazards to human health. The study was mainly designed to study the effect of silver and gold nanoparticles against the enterococcal pathogens. The organisms were also tested against the antibiotics to prove of their susceptibility towards the drugs. The enterococcal pathogens studied here showed a positive response for all the drugs used. The silver and gold nano particles are studied in this context to prove of their effect on the bacterial pathogens. Gold and silver particles are studied separately and are found to show some significant effect on the growth of bacteria. The pathogens studied showed susceptibility towards both the particles (gold and silver). And the effect of the nano particles was completely dose dependent i.e., the effect was found to be more at higher concentration. All effects were statistically significant at the 0.05 significance level. There was a significant effect of the nano particles (gold and silver) among the four different concentrations remembered at the p < 0.05 level. Gold nano particles showed a significance to the concentration [F(1,7) = 13.36364, p = 0.035353].

Key words: Gold nanoparticles, Silver nanoparticles, Enterococcus, MIC

Downloads

Download data is not yet available.

Author Biography

Hamzah Basil Mohammed, Centre for Research & Post graduate studies, Indian Academy Degree College

DEPARTMENT OF BIOTECHNOLOGY

ASSISTANT PROFESSOR

References

Bozzi A, Yuranova T, Kiwi J. Self-cleaning of wool-polyamide and polyester textile by TiO2-rutile modification under daylight irradiation at ambient temperature. J Photochem Photobiol A Chem 2005;172:27‑43.

Li B, Logan BE. Bacterial adhesion to glass and metal-oxide surfaces. Colloids Surf B Biointerfaces 2004;36(2):81-90.

Gebelein CG, Carraher CE. Biotechnology and Bioactive Polymers. New York, London: Plenum Press; 1994.

Bower CK, Parker JE, Higgins AZ, Oest ME, Wilson JT, Valentine BA, et al. Protein antimicrobial barriers to bacterial adhesion: In vitro and in vivo evaluation of nisin-treated implantable materials. Colloids Surf B Biointerfaces 2002;25:81-90.

Reidy DJ, Holmes JD, Morris MA. Preparation of a highly thermally stable titaniaanatase phase by addition of mixed zirconia and silica dopants. Ceram Int 2006;32:235-9.

Studer H. Antimicrobial protection for polyolefin fibers. Chem Fiber Int 1997;47(5):373-4.

Payne J. From medical textiles to smell-free socks. J Soc Dyers Colourists 1997;113:48-50.

Edwards JV, Vigo T. Bioactive Fibers & Polymers. Washington, DC: American Chemical Society; 2001.

Sawada K, Sugimoto M, Ueda M, Park CH. Hydrophilic treatment of polyester surfaces using TiO2 photocatalytic reactions. Text Res J 2003;73:819-22.

Meilert KT, Laubb D, Kiwi J. Photocatalytic self-cleaning of modified cotton textiles by TiO2 clusters attached by chemical spacers. J Mol Catal A Chem 2005;237:101-8.

Mao L, Murphy L. Durable freshness for textiles. AATCC Rev 2001;1:28‑31.

Keshmiri M, Mohseni M, Troczynski T. Development of novel TiO2 sol–gel derived composite and its photocatalytic activities for trichloroethylene oxidation. Appl Catal B 2004;53:209-19.

Ma M, Sun Y, Sun G. Antimicrobial cationic dyes: Part 1: Synthesis and characterization. Dyes Pigm 2003;58(1):27-35.

Montazer M, Afjeh MG. Simultaneous, X-linking and antimicrobial finishing of cotton fabric. J Appl Polym Sci 2007;103:178-85.

Lala NL, Ramaseshan R, Bojun L, Sundarrajan S, Barhate RS, Ying JL, et al. Fabrication of nanofibers with antimicrobial functionality used as filters: Protection against bacterial contaminants. Biotechnol Bioeng 2007;97(6):1357-69.

Mahmoodi NM, Arami M, Limaee NY, Tabrizi NS. Kinetics of heterogeneous photocatalytic degradation of reactive dyes in an immobilized TiO2 photocatalytic reactor. J Colloid Interface Sci. 2006;295:159-64.

Kaushik P, Malik A. Fungal dye decolourization: Recent advances and future potential. Environ Int 2009;35(1):127-41.

Walters PA, Abbott EA, Isquith AJ. Algicidal activity of a surface-bonded organosilicon quaternary ammonium chloride. Appl Environ Microbiol 1973;25:253-6.

Banerjee1 S, Gopal J, Muraleedharan P, Tyagi1 AK, Raj B. Physics and chemistry of photocatalytic titanium dioxide: Visualization of bactericidal activity using atomic force microscopy. Curr Sci 2006;90(10):1378-83.

Vigo T. Antibacterial fiber treatment and disinfection. Text Res J 1981;51:454-65.

Daoud WA, Xin JH. Low temperature Sol–Gel processed photocatalytic titania coating. J Sol–Gel Sci Technol 2004;29:25-9.

Daoud WA, Xin JH, Zhang YH. Surface functionalization of cellulose fibers with titanium dioxide nanoparticles and their combined bactericidal activities. Surf Sci 2005;599:69-75.

Bokhimi X, Morales A, Aguilar M, Antonio JA, Pedraza F. Local order in titania polymorphs. Int J Hydrogen Energy 2001;26:1279-87.

Hasebe Y, Kuwahara K, Tokunaga S. Chitosan hybrid deodorant agent for finishing textiles. AATCC-Rev 2001;1(11):23-8.

Kim YH, Choi HM, Yoon JH. Synthesis of a quaternary ammonium derivative of chitosan and its application to a cotton antimicrobial finish. Text Res J 1998;68(6):428-34.

Wang YL, Zhang KY. Study of the growth morphology of TiO2 thin films by AFM and TEM. Surf Coat Technol 2001;140:155-60.

Published

01-05-2015

How to Cite

Mohammed, H. B., and R. S. Kumar. “ANTIBIOTIC SENSITIVITY OF GOLD AND SILVER NANOPARTICLES AGAINST ENTEROCOCCAL PATHOGENS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 8, no. 3, May 2015, pp. 201-3, https://journals.innovareacademics.in/index.php/ajpcr/article/view/5260.

Issue

Section

Original Article(s)