COMPARISON OF INTRATHECAL NALBUPHINE AND FENTANYL AS ADJUVANTS TO BUPIVACAINE IN SPINAL ANESTHESIA IN PATIENTS UNDERGOING LOWER LIMB SURGERIES
DOI:
https://doi.org/10.22159/ajpcr.2024v17i12.53029Keywords:
Spinal anesthesia,, Fentanyl, Nalbuphine,, Sensory block, Motor blockAbstract
Objective: The objective of this study is to compare nalbuphine 0.5 mg and fentanyl 25 μg when used as an adjuvant to 0.5% bupivacaine heavy in spinal anesthesia for their effect on the sensory block, motor block, and post-operative analgesia.
Methods: After fulfillment of inclusion criteria and after obtaining informed written consent from patients, a group of a total of 80 patients was enrolled and divided in GRP-F and GRP-N equally. (1) Group F: Patients received diluted 25 μg of fentanyl with 3 mL (15 mg) of 0.5% hyperbaric bupivacaine. (2) Group N: Patients received diluted 0.5 mg of nalbuphine with 3 mL (15 mg) of 0.5% hyperbaric bupivacaine.
Results: The duration of sensory block and motor block was significantly longer in GRP-F than GRP-N. Post-operative analgesia was comparable in both groups with minimal side effects.
Conclusion: Intrathecal fentanyl in post-operative period was found to be significantly better than nalbuphine when used as an adjuvant therapy with 0.5% hyperbaric bupivacaine in elective lower limb surgeries with insignificant adverse effects like hypotension, nausea, and vomiting.
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