IN VITRO ASSESSMENT OF FREE RADICAL SCAVENGING ACTIVITY OF JASMINUM GRANDIFLORUM (L.) FLOWER
Abstract
Objectives: The aim of the present study was to evaluate the in vitro free radical scavenging activity of Jasminum grandiflorum flower.
Methods: The free radical potential of ethanoic extract J. grandiflorum was assessed against 2, 2-diphenyl-1-picrylhydrazyl (DPPH), radical, 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic
acid) (ABTS
+
) radical, hydrogen, hydrogen peroxide radical, and ferric reducing antioxidant power assay.
Results: At (20-100 μg/ml) concentration, ethanolic extract of J. grandiflorum flower exhibited free radical quenching capacity against various
antioxidant assays when compared to the standard Vitamin C with increasing percentage of inhibition in a dose-dependent manner. The maximum
percentage of inhibition was shown at the concentration 100 μg/ml.
Conclusion: Hence, the ethanolic extract of J. grandiflorum flower may be a potent source of natural antioxidant and it may be used in the management
of diseases associated with oxidative stress.
Keywords: Jasminum grandiflorum, 2, 2-diphenyl-1-picrylhydrazyl, Antioxidant power assay, Vitamin C, Free radical, Natural antioxidant.
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