QUANTITATIVE ANALYSIS OF BIOACTIVE COMPOUNDS FROM TAGETES ERECTA (LINN.)
Abstract
Objectives: This study investigates the quantitative analysis of the major phytoconstituents of Tagetes erecta (Linn.) and proves their therapeutic
value as medicines in both leaf and flower extracts.
Methods: The various bioactive compounds were quantitatively analyzed as per standard methods.
Results: The present study registered carbohydrates, coumarine, alkaloids, and quinone which are of medicinal importance. During the study, quinone
recorded the highest amount of phytocomponents in both the leaf and flower samples.
Conclusion: The significant result of the present study revealed that the flower extract exhibited more amounts of phytochemicals than the others,
and this could be exploded for potential drug development in future.
Keywords: Phytoconstituents, Coumarine, Alkaloids, Quinone, Extraction, Solvents.
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Tariq AL, Reyaz AL. Quantitative phytochemical analysis of
traditionally used medicinal plant Terminalia chebula. Int Res J
Biotechnol 2013;4(5):101-5.
Sangeetha M, Preethi S. Qualitative and quantitative analysis of
bioactive compounds in Morinda citrifolia fruit. Indian J Adv Plant Res
;16:5-8.
Ncube NS, Afolayan AJ, Okah AL. Assessment technology of
antimicrobial properties of natural compounds of plant origin: Current
methods and future trends. Afr J Biotechnol 2008;7(12):1797-806.
Abu-Rabia A. Urinary diseases and ethnobotany among pastoral
nomads in the Middle East. J Ethnobiol Ethnomed 2005;1:4.
Raveen N, Nayak S, Kar DM, Das P. Pharmacological evaluation
of ethanolic extracts of the plant Altermanthera sessilis against
temperature regulation. J Pharm Res 2010;3(6):1381-3.
Harbome JB. Phytochemical Methods. London: Chapman and Hail.
Ltd.; 2012. p. 49-133.
Raja A, Gajalakshmi P, Raja MM. Drugs from the natural bio sources
for human diseses. Int J Pharm 2010;463:360-3.
Jasuja ND, Saxena R, Chandra S, Sharma R. Pharmacological
characterization and beneficial uses of Punica granatum. Asian J Plant
Sci 2012;11:251-7.
Saxena R, Sharma R, Nandy BC, Jasuja ND. Qualitative and
quantitative estimation of bioactive compounds in Mimosa hamata. Int
J Pharm Pharm Sci 2014;6(6):72-5.
Edeoga W, Taxeira EW, Negri G, Saltino A. Plant origin of green
propolis: Plant anatomy and chemistry. Evidence based complementary
alternative medicine. Int J Pharm 2005;2:85-92.
Daniel G, Krishakumari S. Quantitative analysis of primary and
secondary metabolites in aqueous hot extract of Eugenia uniflora (L)
leaves. Asian J Clin Res 2015;8(1):334-8.
Rajalekharan PE. Herbal medicine. In: World of Science. Employ News
;21(27):3.
Humadi SS, Istudor V. Quantitative analysis of bioactive compound
Hibiscus sabadariffa L. extracts Note 1: Quantitative analysis of
flavonoids. Farmacia 2008;LVI, 6:699-707.
Steinmetz KA, Potter JD. Vegetables, fruit, and cancer. II. Mechanisms.
Cancer Causes Control 1991;2(6):427-42.
Harborne JB, Williams CA. Advances in flavonoid research since 1992.
Phytochemistry 2000;55(6):481-504.
Bruneton J. Pharmacognosie: Phytochemie, Plantes Medicinal. Paris:
TEC and DOC, Lavoisier; 1999. p. 310-7.
Istudor V. Farmacognozie, Fitochimie, Fitoterpie. Vol. 1. Scientific
Basis Boca Raton: Medicala Bucuresti; 1998. p. 148-50.
Bodea C. Manuals for universities and higher education institutes, vol
, Wasshington DC, Educational Academic Bureau, 1965, p.889-13.
Brachadeo V. Physicians Disk Reference. Montvale: Thomson PDR;
p. 435-6.
Bisset N, Witchtl M. Herbal Drugs and Phytopharmaceuticals: A Hand
Book for Practice on a Scientific Basis. Boca Raton, Ann Arbor,
London, Tokyo: CRC Press; 1994. p. 266-7.
Sukanya MK, Suku S, Aruna SR. Phytochemical analysis, antimicrobial
screening and antihelminthic properties of Phyllanthus emblica. Int J
Pharm Biol Sci 2013;4(4):55-64.
Srinivasan M. Vitamin C in plants: Indian gooseberry Phyllanthus
emblica. Nature 1994;153:684-8.
Dhale DA. Pharmacognistic evaluation of Phyllanthus emblica Linn.
(Euphorbiaceae). Int J Pharm Biol Sci 2012;3(3):210-7.
Raghu HS, Ravindra P. Antimicrobial activity and phytochemical study
of Phyllanthus emblica Linn. J Pharmacol 2010;14:119-28.
Summanen JO. An anti-inflammatory activity of extracts from leaves of
Phyllanthus emblica. Plant Med 1997;63:518-24.
Faisal M, Sing PP, Ircchariya R. Review on Albizia lebbeck - A potent
herbal drug. Int Res J Pharm 2012;3(5):63-8.
Babu NP, Pandikumar P, Ignacimuthu S. Anti-inflammatory activity of
Albizia lebbeck Benth. an ethnomedicinal plant, in acute and chronic
animal models of inflammation. J Ethnopharmacol 2009;125(2):356-60.
Sanjay K. Saponins of Albizia lebbek in Alzheimer’s and Parkinson’s
disease. Int J Nat Prod 2003;19:42-8.
Souravi K, Rajasekharan PE. A review on the pharmacology of Embella
ribes Burm F.A threatened medicinal plant. Int J Pharm Biol Sci
;5(2):443-56.
Mitra R. Vidanga (Embelia ribes) an Ayurvedic drug can help family
planning. Appl Bot Abstr 1995;15(4):267-82.
Durate MR, Debur MC. Character of the leaf and stem morphoanatomy
of
Altermanthera
brasiliana
(L.)
O. Kuntze, Amaranthaceae.
Braz
J Pharm Sci 2004;40(1):85-92.
Brochado CO, Almeido AP, Barreto BP, Costa LP, Ribeito LS,
Pereira RL. Flavonol robinnobiosides and rutinosides from
Alternanthera brasiliana (Amaranthaceae) and their effects on
lymphocyte proliferation in vitro. J Braz Chem Soc 2003;14(3):449-51.
Devika R, Koilpillai J. Phytochemical screening studies of bioactive
compounds of Tagetes erecta. Int J Pharm Biol Sci 2012;3(4)
(B):596-602.
Devika R, Koilpillai J. Screening and evaluation of bioactive
components of Tagetes erecta L. by GC-MS analysis. Asian J Pharm
Clin Res 2014;7(2):58-60.
Devika R, Koilpillai J. Column chromatographic separation of
bioactive compounds from Tagetes erecta Linn. Int J Pharm Sci Res
;6(2):762-6.
Suresh Kumar CA, Varadharajan R, Muthumani P, Meera R, Devi P,
Kameswari B. Pharmacognostic and preliminary investigations on the
Asian J Pharm Clin Res, Vol 8, Issue 6, 2015, 185-187
Devika and Koilpillai
stem of Saccharum spontaneum. J Pharm Sci Res 2009;1(3):129-6.
Ayoolal GA, Cokerl HA, Adesegun AA, Bellol A, Obaweyal K,
Ezennial TO, et al. Phytochemical screening and antioxidant activities
of some selected medicinal plants used for malaria therapy in
Southwestern Nigeria. Trop J Pharm Res 2008;7(3):1019-24.
Hedge JE, Hofreiter BT. In: Carbohydrate Chemistry. 17
ed. New York:
Academic Press; 1962.
th
Singh R, Jasrai YT. Mimosa hamate (Wild) aplant with antipathogenic
properties. Int J Med Aromat Plants 2012;2:677-83.
Agitey Smith E, Addae Mensah I. Phytochemical, nutritional and
medicinal properties of some leafy vegetables consumed by Edo people
of Nigeria. West Afr J Pharm Drug Res 1977;4:7-8.
Bonjean K, De Pauw Gillet MC, Defresne MP, Colson P, Houssier C,
Dassonneville L. Physicochemical analysis of leaf extract of some
trpical medicinal plants. J Ethanopharmcol 1998;69:241-6.
Di Carlo G, Mascolo N, Izzo AA, Capasso F. Flavonoids: Old
and new aspects of a class of natural therapeutic drugs. Life Sci
;65(4):337-53.
Obdoni BO, Ochuko PO. Phytochemical studies and comparative
efficacy of the crude extracts of some homostatic plants in Edo and
Delta states of Nigeria. Glob J Pure Appl Sci 2001;8:203-8.
Freeze HH. Disorders in protein glycosylation and potential therapy:
Tip of an iceberg? J Pediatr 1998;133(5):593-600.
Prashith KT, Vihyaka KS, Soumya KV, Ashwini SK, Kiran R.
Antibacterial and antifungal activity of methanolic extract of Abrus
pulchellus wall and Abrus precatorius Linn. A comparative study. Int J
Toxicol Pharmacol Res 2010;2(1):26-9.
Luziatelli G, Sorensen M, Thellade L, Molgaard L, Bhattacharya S,
Haldar PK, et al. Evaluation of anti-inflammatory activity of Vernonia
cinera Less extracts in rats. Phytomedicines 2010;6:21-7.
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