BRINE SHRIMP CYTOTOXIC ACTIVITY OF 50% ALCOHOLIC EXTRACT OF CROTON BONPLANDIANUM BAILL.
Abstract
Objective: To study the presence of anti-tumorous compounds in Croton bonplandianum. Methods: 50 % ethanolic extract, obtained from dried powdered plant material of C. bonplandianum was assayed for its Brine shrimp cytotoxic activity. Results: It was found that the extract was very effective against brine shrimp and shows LC50 at the concentration of 46.7mg/lit (38 mg/lit -55 mg/lit). Conclusions: It proves the presence of anti-tumorous compounds in C. bonplandianum.Downloads
References
Singh Saggoo M I, Walia S, Kaur R. Evaluation of genotoxic and antimicrobial potential of Croton bonplandianum Baill. Scholars Research Library- Archives of Applied Science Research. 2010;2 (2):211-216
Ahmad R, Khan AV, Siddiqui MF, Hasnain AU. Effects of an aqueous extract of Croton bonplandianum Baill in rats; Environ. Toxicol. Phar. 2008; 26(3):336-41.
Asthma A, Mall H V, Dixit K, Gupta S. Fungitoxic Properties of Latex of Plants with Special Reference to that of Croton bonplandianum Baill. Pharm. Biol. March 1989; 27 (1) : 25 – 28
Islam MS, Rahman MM, Rahman MA, Qayum MA , and Alam MF. In vitro evaluation of Croton bonplandianum Baill. as potential antitumor properties using Agrobacterium tumefaciens. J. Agri. Tech. 2010; 6(1): 79-86
McLaughin J L, Rogers L L. The use of biological assays to evaluate botanicals, Drug information Journal. 1998; 32: 513-524
Meyer BN, Ferrigni NR, Putnam JE, Jacobsen LB, Nichols DE, McLaughlin JL. Brine shrimp: a convenient general bioassay for active plant constituents, Planta Med. 1982; 45(5):31-4
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