DIFFERENCES IN THE EFFECT OF APPLYING 15% HYDROXYAPATITE PASTE FROM GOLDFISH SCALES (CYPRINUS CARPIO) WITH CASEIN PHOSPHOPEPTIDE–AMORPHOUS CALCIUM PHOSPHATE (CPP-ACP) AS A REMINERALIZING MATERIAL ON ENAMEL SURFACE HARDNESS

Authors

  • FITRI YUNITA BATUBARA Department of Conservative Dentistry, Faculty of Dentistry, Universitas Sumatera Utara, Medan, Indonesia https://orcid.org/0000-0002-4159-9748
  • WILLIAM SAHALA MARKUS SITOMPUL Dental Student, Faculty of Dentistry, Universitas Sumatera Utara, Medan, Indonesia https://orcid.org/0009-0003-2198-8054

DOI:

https://doi.org/10.22159/ijap.2024.v16s2.02

Keywords:

Goldfish scale, Remineralization, Hydroxyapatite, Micro vickers hardness tester

Abstract

Objective: Caries is a multifactorial disease that affects most of the world's population and is a detrimental factor for oral health. Demineralization on teeth can reduce the hardness of the enamel surface, which causes enamel to be susceptible to caries. The purpose of this study was to determine the effect of giving 15% hydroxyapatite paste from goldfish scales (Cyprinus carpio) with CPP-ACP as a remineralizing agent on the enamel surface hardness.

Methods: This laboratory experimental study using 24 samples of post-extraction maxillary first premolars. There were 4 groups of samples, group I samples that were not given the test material were only soaked in artificial saliva, group II samples were only demineralized with HCl solution for 120 seconds, both test groups were then demineralized with HCl solution for 120 seconds before being given the test material. Group III samples were applied with the test material CPP-ACP for 2 min; group IV samples were applied with 15% goldfish scale hydroxyapatite paste (Cyprinus carpio) for 2 min. Both test groups were given treatment for 14 consecutive days. All sample groups were tested for surface hardness using the Microvickers Hardness Tester.

Results: The results of the Mann-Whitney analysis test showed that there was a significant difference in the effect of pn<0.05 between each group studied. Based on the results of the study, there was an effect after administration of 15% hydroxyapatite paste of goldfish scales (Cyprinus carpio) with CPP-ACP as a remineralizing agent on enamel surface hardness.

Conclusion: Based on the results of research on the effect of administering 15% goldfish (Cyprinus carpio) scale hydroxyapatite paste with Casein Phosphopeptide–Amorphous Calcium Phosphate (CPP-ACP) on enamel surface hardness, it can be concluded that there is a significant effect after administering goldfish (Cyprinus carpio) scale hydroxyapatite paste 15 % and CPP-ACP on enamel surface hardness.

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Published

27-05-2024

How to Cite

BATUBARA, F. Y., & SITOMPUL, W. S. M. (2024). DIFFERENCES IN THE EFFECT OF APPLYING 15% HYDROXYAPATITE PASTE FROM GOLDFISH SCALES (CYPRINUS CARPIO) WITH CASEIN PHOSPHOPEPTIDE–AMORPHOUS CALCIUM PHOSPHATE (CPP-ACP) AS A REMINERALIZING MATERIAL ON ENAMEL SURFACE HARDNESS. International Journal of Applied Pharmaceutics, 16(2), 6–8. https://doi.org/10.22159/ijap.2024.v16s2.02

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