DEVELOPMENT OF EXTRACTIVE SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF IRON (III) WITH SCHIFF BASE 2-[(2-HYDROXYPHENYLIMINO) METHYL]-4-NITROPHENOL

Datta B. Mandhare; Vasant D. Barhate

doi:10.22159/ijcpr.2016v8i4.15924

Authors

Datta B. Mandhare V. E. S. College of Art, Science and Commerce, Sindhi Society Chembur, Mumbai 400071, India
Vasant D. Barhate V. E. S. College of Art, Science and Commerce, Sindhi Society Chembur, Mumbai 400071, India

DOI:

https://doi.org/10.22159/ijcpr.2016v8i4.15924

Keywords:

Solvent Extraction, Extractive Spectrophotometry, Iron (III), Schiff base, 2-[(2-hydroxyphenylimino) methyl]-4-nitrophenol [HPIMNP], Pharmaceutical sample

Abstract

Objective: A simple spectrophotometric method has been developed for the determination of Iron (III) by using Schiff base 2-[(2-hydroxyphenylimino) methyl]-4-nitrophenol [HPIMNP].

Methods: HPIMNP extracts Fe (III) quantitatively (99.95%) into chloroform from an aqueous solution of pH range 4.0-6.0.

Results: The chloroform extracts show maximum absorption at 510 nm (Î» max). Beer's Law is obeyed over the Fe (III) concentration range of 0.5 to 20.0 Âµg/ml. The Molar absorptivity and Sandell's sensitivity for Feâ€“HPIMNP system is 5000 L mol Ë‰¹ cmË‰¹ and 0.011 Âµg cmË‰²respectively. The composition of extracted species is found to be 1: 3 [Fe-HPIMNP] by Job's continuous variation and Mole-ratio method. Interference by various ions has been studied.

Conclusion: The proposed method is rapid, sensitive, reproducible and accurate and it has been satisfactory applied for the determination of Iron in Pharmaceutical Samples.

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