STANDARDISATION AND PHYTOCHEMICAL SCREENING OF TRADITIONAL FORMULATION
DOI:
https://doi.org/10.22159/ijcpr.2017v9i1.16617Keywords:
Traditional formulations, Organoleptic character, Physiochemical, Phytochemical screeningAbstract
Objective: The main objective of this study is to standardise and evaluate traditional formulation both qualitatively and quantitatively on the basis of organoleptic characteristics, physical characteristics, physiochemical properties and phytochemical screening.
Methods: Traditional formulation (TF) containing seven traditionally used herbs were collected from local areas and market. The plants were washed, air-dried and coarsely powdered. The aqueous extract was prepared as per literature, and various physiochemical, phytochemical screening was done.
Results: The organoleptic character shows the drug with greenish colour, slightly bitter taste and characteristic odour. The physiochemical properties show the appropriate pH and the solubility of TF. Secondary metabolites like phenolic compounds and flavonoids are present abundantly in aqueous extract than in other extracts.
Conclusion: Our studies suggests that TF contains medicinally important secondary metabolites which has disease protective properties. This study will help in the progression of a suitable monograph, determining the quality and purity of a crude extract and laying down pharmacopoeia standards for the formulation.
Downloads
References
Jarald EE. Textbook of pharmacognosy and phytochemistry. 1st ed. CBS publication, Delhi; 2009.
Indian Pharmacopoeia. Vol III. Controller of Publications, Ghaziabad; 2007. p. 2034-57.
World Health Organization (WHO). Quality Control Methods for Medicinal Plant Materials. AITBS Publishers, Delhi; 2002. p. 46-51.
Badugu LR. Phytochemical screening, quantitative estimation total phenolics and total flavonoids, anti-microbial evaluation of Cyamopsistetragonoloba. Int J Res Pharm Biomed Sci 2012;3:1139-42.
Parekh J, Karathia N, Chanda S. Evaluation of antibacterial activity and phytochemical analysis of Bauhinia variegataL. bark. Afr J Biomed Res 2006;9:53-6.
Shanmugapriya K, Saravana PS, Payal H, Mohammed P, Binnie W. A comparative study of antimicrobial potential and phytochemical analysis of Artocarpusheterophyllusand Manilkarazapotaseed extracts. J Pharm Res 2011;4:2587-9.
Kalaiselvan V, Kalpeshkumar SA, Patel FB, Shah CN. Quality assessment of different marketed brands of Dasamoolaristam, an ayurvedic formulation. Int J Ayurveda Res 2010;1:10â€1.
Vaidya Ratnam KS, Murugesa Mudaliar. Gunapadam. (Siddha Materia Medica) 1st edition; 1936. p. 229,345,459,520,720.
Tharakan Sheeja T, Kuttan Girija, Kuttan Ramadasan, Kesavan, Austin. Immunostimulatory action of AC II--an ayurvedic formulation useful in HIV. Indian J Exp Biol 2008;46:47-51.
Siddiqui, Hakim MA. Format for the pharmacopoeial analytical standards of compound formulation, workshop on standardization of Unani drugs, (appendix), New Delhi: Central Council for Research in Unani Medicine (CCRUM); 1995.
Kokate CK, Purohit AR, Gokhale SB. Pathway to Screen Phytochemical nature of Natural Drugs. Pharmacognosy. 42nd ed. Pune, Nirali Prakashan; 2008. p. 56-61.
Srivastava NK, Shreedhara CS, Aswatha Ram HN. Standardisation of Ajmodadichurna, a polyherbal formulation. J Pharmacogn Res 2010;2:98â€101.
Kokoshi CJ, Kokski RJ, Sloma FJ. Methods for the analysis of various compound in plants. J Pharmacogn Assoc 1958;10:716.
Chase CR, Pratt RJ. Fluorescence of powdered vegetable drugs with particular reference to the development of a system of identification. J Am Pharm Assoc 1949;38:324â€31.
Rakesh S Shivatare, Ashish S Pande, Hanumant U Bhusnar, Prasad V Kadam, Kavita N Yadav, et al. Standardization of narasimha churna: a poly-herbal formulation. Asian J Biomed Pharm Sci 2013;3:23-7.
Singleton VL, Orthofer R, Lamuela-Raventos RM. Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteau reagent. Methods Enzymol 1999;299:152-78.
Adeniyi SA, Orjiekwe CL, Ehiagbonare JE. Determination of alkaloids and oxalates in some selected food samples in Nigeria. Afr J Biotechnol 2009;8:110-2.
Zhishen J, Mengcheng T, Jianming W. The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chem 1999;64:555-9.
Zou Y, Lu Y, Wei D. Antioxidant activity of a flavonoid-rich extract of Hypericumperforatum L in vitro. J Agric Food Chem 2004;52:5032-9.
Hussain J, Jamila N, Gilani SA, Abbas G, Ahmed S. Platelet aggregation, antiglycation, cytotoxic, phytotoxic and antimicrobial activities of extracts of Nepetajuncea. Afr J Biotechnol 2009;8:935-40.
VC Devaraj, B Gopala Krishna, GL Viswanatha. Hepato-protective activity of Hepax-A polyherbal formulation. Asian Pac J Trop Biomed 2011;1:142-6.
Shrivastava Surabhi, Leelavathi S. Preliminary phytochemical evaluation of leaf extracts of catunaregumspinosa thunb. Int J Pharm Sci Rev Res 2010;3 :100-8.
Published
How to Cite
Issue
Section
