SUBLINGUAL DRUG DELIVERY: AN INDICATION OF POTENTIAL ALTERNATIVE ROUTE

Puja Saha; Sushma Verma; Pratik Swarup Das

doi:10.22159/ijcpr.2017v9i6.23436

Authors

Puja Saha Noida Institute of Engineering and Technology
Sushma Verma Pharmacy Institute, Noida Institute of Engineering and Technology
Pratik Swarup Das Noida Institute of Engineering and Technology

DOI:

https://doi.org/10.22159/ijcpr.2017v9i6.23436

Keywords:

Sublingual route, Patient compliance, Dysphagia, Sublingual technologies

Abstract

Sublingual literally meaning is under the tongueâ€, refers to a method of administrating substance via mouth in such a way that the substance is rapidly absorbed via blood vessels under tongue. Sublingual route is a useful when rapid onset of action is desired with better patient compliance than orally ingested tablets. Drugs that are given sublingually reach directly in to the systemic circulation through the ventral surface of the tongue and floor of the mouth. The portion of drug absorbed through the sublingual blood vessels bypasses the hepatic firstâ€pass metabolic processes giving acceptable bioavailability. As nowadays most of the people need effective relief within a short period of time so sublingual is the most suitable form of administration. New sublingual technologies address many pharmaceutical and patient needs, ranging from enhanced lifeâ€cycle management to convenient dosing for paediatric, geriatric, and psychiatric patients with dysphagia.

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