IN VITRO ANTHELMINTIC ACTIVITY OF IPOMEA AQUATICA
DOI:
https://doi.org/10.22159/ijcpr.2018v10i3.27338Keywords:
Anthelmintic activity, ipomeaaquatica, Albendazole, Ethanolic extract, PheretimaposthumaAbstract
Objective: The present study was aimed at the evaluation of in vitro anthelmintic activity of ethanolic leaf extract of ipomeaaquatica against Indian earthworm Pheretimaposthuma.
Methods: Four concentrations (25 mg/ml, 50 mg/ml, 75 mg/ml, 100 mg/ml) were tested and results were expressed in terms of time for paralysis and time of the death of worms. In this study, Albendazole was used as a standard drug.
Results: Ethanolic leaf extract of ipomea aquatic showed significant activity at higher concentrations when compared to standard group (Albendazole).
Conclusion: It can be concluded that the ethanolic leaf extract of Ipomeaaquaticahas shown more significant anthelmintic activity when compared to Albendazole against Indian earthworm Pheretimaposthuma.
Downloads
References
infection I: The global burden of intestinal nematode disease. Trans R Soc Trop Med Hyg 1994;8:259–61.
Rafi Khan P. Anthelmintic activity of nerium oleander flower extract in Indian adult earthworm. J Natural Product Plant Resources 2011;1:40-6.
Sondhi SM, Shahu R, Magan Archana. Anthelmintic activity of platycladusorientalis leaves extract. Indian Drugs 1994;31:317-20.
Kangkong/Ipomoea aquatica Forsk./POTATO VINE/Herbal Medicinal Therapies/Philippine Alternative Medicine". Stuartxchange.org; 2014.
Growing kangkong in water. curiousgardener.com. [Last accessed on 10 Dec 2017]
Kangkungking.com. Kangkungking.com. [Last accessed on 20 Nov 2012].
Dua TK, Dewanjee S, Gangopadhyay M, Khanra R, Zia-Ul-Haq M, De Feo V. Ameliorative effect of water spinach, Ipomoea aquatic (Convolvulaceae), against experimentally induced arsenic toxicity. JTransl Med. 2015;13:81.
Chopra RN, Nayar SL, Chopra IC. Glossary of Indian medicinal plants. New Delhi, India: Council of Scientific and Industrial Research; 1956.
Badruzzaman SM, Husain W. Some aquatic and marshy land medicinal plants from Hardoi district of Uttar Pradesh. Fitoterapia 1992;63:245-7.
Samuelsson G, Farah MH, Claeson P, Hagos M, Thulin M, Hedberg O, et al. Inventory of plants used in traditional medicine in somalia II. Plants of the families Combretaceae to Labiatae. J Ethnopharmacol 1992;37:47-70.
Cornelius J, Nugteren JA, Westphal E. Kang-kong (Ipomoea aquaticaForssk). An important leaf vegetable in Southeastern Asia. Abstracts Trop Agric 1985;10:9-21.
Trease GE, Evans WC. Pharmacognosy, London. ELBS 1989;223:246-9.
T Ghosh, TK Maity, Bose A, Dash GK. Indian Journal of Natural Product; 2009. p. 16-9.
Adnaik RS, Bhagwat DA, Raut ID, Mohite SK, Magdum CS. Laxative and anthelmintic potential of Cassia alata flower extract. Res J Pharm Technol 2011;4:98-100.
Kane SR, Adnaik RS, Apte VA, Magdum CS. In vitro anthelmintic activity of senna occidentalis. Res J Pharmacognosy Phyto Chem 2017;2:182-4.