QUANTITATIVE ESTIMATION OF MAGNESIUM CARBONATE IN PAN MASALA AND GUTKA
DOI:
https://doi.org/10.22159/ijcpr.2018v10i5.29691Keywords:
Carcinogenic, Magnesium Carbonate, Water soluble extract, EDTA, Pan Masala, Gutka etcAbstract
Objective: The objective of present study is to detect and quantitatively estimate Magnesium Carbonate, a potential carcinogen used for its anti-caking property in various brands of Pan Masala and Gutka by the simple, economic and effective method.
Methods: The water-soluble extract of various brands of Pan Masala and Gutka was prepared by a wrist action rotary shaker for 60 min. The extract was filtered, and the filtrate was titrated against 0.1N EDTA using Eriochrome Black T indicator at pH 10 and using Murexide indicator at pH 12.
Results: The presence of Magnesium Carbonate was found to be less than 2% in all brands of Pan Masala and less than 3% in all brands of Gutka samples used in the analysis.
Conclusion: There is Magnesium Carbonate used in all brands of Pan Masala and Gutka used in the present study.
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References
Nigam SK, Bhatt HV. Analysis and toxicity of plain (PMP) and blended (PMT) Indian Pan Masala (PM). Eurasian J Med 2013;45:21-33.
Javed F, Bello Correa FO, Chotai M, Tappuni AR, Almas K. Systemic conditions associated with areca nut usage: a literature review. Scand J Public Health 2010;38:838–44.
Shah G, Chaturvedi P, Vaishampayan S. Arecanut as an emerging etiology of oral cancers in India. Indian J Med Paediatr Oncol 2012;33:71–9.
Niaz K, Maqbool F, Khan F, Bahadar H, Hassan FI, Abdollahi M. Smokeless tobacco (paan and gutkha) consumption, prevalence, and contribution to oral cancer. Epidemiol Health 2017;39:e2017009.
Banerjee SC, Ostroff JS, Bari S, D’Agostino TA, Khera M, Acharya S, et al. Gutka and Tambaku paan use among South Asian immigrants: a focus group study. J Immigr Minor Health 2014;16:531–9.
Garg A, Chaturvedi P, Mishra A, Datta S. A review on harmful effects of pan masala. Indian J Cancer 2015;52:663-6.
Gupta PC. Gutka: a major new tobacco hazard in India. Tob Control 1999a;8:134.
https://vovindia.org/ [Last accessed on 08 May 2018]
Awan KH, Hussain QA, Patil S, Maralingannavar M. Assessing the risk of oral cancer associated with gutka and other smokeless tobacco products: a case-control study. J Contemp Dent Pract 2016;17:740-4.
Hussain Z, Nazir A, Shafique U, Salman M. Comparative study for the determination of metals in milk samples using flame-AAS and EDTA complexometric titration. J Sci Res 2010;XXXX:9-14.
Varale Y. Study of total hardness present in the tube-well water sample of Nipani town. IJAPSA 2016;2:81-4.
Gupta PC, Shreevidya S. Final report of the project on laboratory testing of smokeless tobacco products/Researchgate. Available from: https://www.researchgate.net/. [Last accessed on 08 Jul 2018].
Food Safety and Standards Regulations; 2011.