• HARSH RASTOGI Ram-Eesh Institute of Vocational and Technical Education (Department of Pharmacy), Greater Noida, U. P.
  • HRISHAV DAS PURKAYASTHA Acharya and BM Reddy College of Pharmacy, Hesarghatta Main Road, Bengaluru, Karnataka
  • SHALINI TIWARI Sunderdeep Pharmacy College, Dasna-Delhi Highway, Ghaziabad, U. P.



Conventional drug delivery system, Novel drug delivery system, Micelles, Neosomes, Microparticles


An existing drug in the conventional dosage form is evolution in to novel drug delivery system which can significantly enhances and improves the performance of drug in terms of drug safety, drug efficacy as well as patient compliance. With the help of appropriate novel approaches, an existing drug molecule can get a new life and can be a major advance solution for the problems towards the release of drug at specific site and specific rate. The main aim of novel drug delivery system is to minimize the drug loss and drug degradation which can be achieved by targeting the drug to the site of interest. With the help of soluble or insoluble biodegradable natural and synthetic polymers different novel formulations can be formulated as microparticles, microcapsules, liposomes, neosomes, micelles etc. Targeting is based on active targeting and passive targeting mechanisms for drug release. This review covers the basic information on Novel Drug Delivery Systems (NDDS).


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1. Torchilin VP. Structure and design of polymeric surfactant-based drug delivery systems. J Controlled Release 2001;73:137-72.
2. Muller Goymann CC. Physicochemical characterization of colloidal drug delivery systems such as reverse micelles, vesicles, liquid crystals, and nanoparticles for topical administration. Eur J Pharm Biopharm 2004;58:343-56.
3. Haag R. Supramolecular drug-delivery systems based on polymeric core-shell architectures. Angew Chem Int Ed 2004;43:278-82.
4. S Varun, R Kapoor, K Preet. Taste masking and formulation of ofloxacin rapid disintegrating tablets and oral suspension. Indian J Pharm Educ Res 2009;43:150-5.
5. Dwarakanadha Reddy P, Swarnalatha D. Recent advances in novel drug delivery systems. Int J Pharm Tech Res 2010;2:2025–7.
6. Verma RK, Krishna DM, Garg S. Formulation aspects in the development of osmotically controlled oral drug delivery systems. J Controlled Release 2002;79:7–27.
7. Zentner GM, McClelland GA, Sutton SC. Controlled porosity solubility-and resin-modulated osmotic drug delivery systems for the release of diltiazem hydrochloride. J Controlled Release 1991;16:237–44.
8. Lindstedt B, Ragnarsson G, Hjartstam J. Osmotic pumping as a release mechanism for membrane-coated drug formulations. Int J Pharm 1989;56:261–8.
9. Ghosh T, Ghosh A. Drug delivery through the osmotic systems-an overview. J Appl Pharm Sci 2011;2:38–49.
10. Reddy PD, Swarnalatha D. Recent advances in novel drug delivery systems. IJPTR 2010;2:2025-7.
11. Muller CC. Physicochemical characterization of colloidal drug delivery systems such as reverse micelles, vesicles, liquid crystals and nanoparticles for topical administration. Eur J Pharm Biopharm 2004;58:343-56.
12. Arunachalam A, karthikeyan M, Vinay Kumar D. Transdermal drug delivery system: a review. Curr Pharma Res 2010;1:70-81.
13. Sharma B, Saroha K, Yadav B. Sonophoresis: an advanced tool in the transdermal drug delivery system. IJCPR 2011;3:89-97.
14. Gupta S, Singh RP, Sharma R, Kalyanwat R, Lokwani P. Osmotic pumps: a review. IJCP 2011;6:1-8.
15. Patel H, Patel U, Kadikar H, Bhimani B, Daslaniya D, Patel G. A review on osmotic drug delivery system. IRJP 2012;3:88-94.
16. Kumar A, Sharma P, Banik A. Microencapsulation as novel drug delivery system. Int Pharm Sci 2011;1:1-7.
17. Saraf AS. Applications of novel drug delivery system for herbal formulations. Fitoterapia 2010;81:680-9.
18. He ZF, Liu DY, Zeng S, Ye JT. Study on preparation of ampelopsin liposomes. China J Chin Mater Med 2008;33:27-30.
19. Rane S, Prabhakar B. Influence of liposome composition on paclitaxel entrapment and pH sensitivity of liposomes. IJPTR 2009;1:914-7.
20. Godin B, Touitou E. Mechanism of bacitracin permeation enhancement through the skin and cellular membrane from an ethosomal carrier. J Controlled Release 2004;94:365-79.
21. Jzu-Hui Wu, Feng-Lin Yen, Liang-Tzung Lin, Tong-Rong Tsai, Chun-Ching Lin. Preparation, physicochemical characterization, and antioxidant effects of quercetin nanoparticle. IJP 2008;346:160-8.
22. Sampath Kumar KP, Bhowmik D, Chiranjib Chandira M, Tripathi KK. Innovations in sustained release drug delivery system and its market opportunities. J Chem Pharm Res 2010;2:349-60.



How to Cite

RASTOGI, H., H. D. PURKAYASTHA, and S. TIWARI. “PHARMACEUTICAL WORLD WITH INNOVATIVE APPROACHES-A REVIEW”. International Journal of Current Pharmaceutical Research, vol. 11, no. 5, Sept. 2019, pp. 14-17, doi:10.22159/ijcpr.2019v11i5.35700.



Review Article(s)