• RUSLIN Faculty of Pharmacy, Halu Oleo University, Kendari, Southeast Sulawesi, Indonesia
  • VICA ASPADIAH Faculty of Pharmacy, Halu Oleo University, Kendari, Southeast Sulawesi, Indonesia
  • DIAH DHIANAWATY Biochemistry and Biomolecular Laboratory, Medical Faculty, Padjadjaran University, Bandung, West Java, Indonesia



Antihyperglycemic, Cogongrass, Glucose absorption, I cylindrical


Objective: This study aims to evaluate the inhibitory activity of Imperatacylindrica root methanol extract on glucose absorption level in intestine of male Wistar strain rats at a dose of 90 mg/kg-bw, which is a dose having antihypertensive activity.

Methods: Extract inhibitory activity on the glucose absorption level in the intestine of the rats followed Soedigdo-Marsongkohadi method. Glucose absorption level was measured from a mixture of 30 mmol glucose in 0.9 % sodium chloride solution as the control solution and a mixture of the extract at the dose of 90 mg/kg-bw in another control solution as the tested solution

Results: The result showed that the extract at the dose of 90 mg/kg-bw had significant activity (p<0.05) to decrease the glucose absorption level in the intestine of the rats.

Conclusion: I. cylindrica root methanol extract at the dose of 90 mg/kg-bw had a significant activity to inhibit the glucose absorption level in the intestine of the rats. Thereby, the extract at the dose of 90 mg/kg-bw had antihyperglycemic activity.


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How to Cite

RUSLIN, V. ASPADIAH, and D. DHIANAWATY. “ANTIHYPERGLYCEMIC ACTIVITY OF IMPERATA CYLINDRICA ROOT METHANOL EXTRACT IN RATS”. International Journal of Current Pharmaceutical Research, vol. 12, no. 3, May 2020, pp. 140-3, doi:10.22159/ijcpr.2020v12i3.38324.



Original Article(s)