MESUA FERREA LINN. (NAGKESAR): A POTENT ANTIMICROBIAL PLANT SPECIES
DOI:
https://doi.org/10.22159/ijcpr.2021v13i4.42734Keywords:
Mesua ferrea, Antimicrobial activity, Nagkesar, Cobra saffron, AyurvedaAbstract
Many plants have not been investigated thoroughly, which are used traditionally as a medicine to cure various diseases. Herbal plants play a vital role in the development of new drugs which can be used for various therapeutic indications. Mesua ferrea linn., commonly known as 'Nagchampa' or 'Nagkesar', is one such herbal plant having many potential therapeutic activities. It is used in diseases like rheumatism, asthma, inflammation, fever, dyspepsia, renal diseases, dysentery, bleeding piles, a bacterial and fungal infection. This plant possesses many bioactive chemical constituents like coumarins, xanthones, pyranoxanthones, flavonoids, terpenoids and steroids which can be easily isolated. It can act as precursors on many ailments. These bioactive constituents have many pharmacological activities such as anticancer, antimicrobial, antifungal, anti-inflammatory, anti-arthritis, analgesic, diuretic, anti-hemorrhoid, antiulcer and many more. Almost every part of the plant is reported to have beneficial medicinal properties. But further studies are still needed to explore the pharmacological activities of Mesua ferrea linn. plant so as to gain benefit for the treatment of various diseases. This review highlights the general description, phytochemical profiling, traditional uses and proven pharmacological attributes of Mesua ferrea linn. plant.
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2. Simmler C, Graham JG, Chen SN, Pauli GF. Integrated analytical assets aid botanical authenticity and adulteration management. Fitoterapia 2018;129:401-14.
3. Ayyanar M, Ignacimuthu S. Ethnobotanical survey of medicinal plants commonly used by Kani tribals in Tirunelveli hills of Western Ghats, India. J Ethnopharmacol 2011;134:851-64.
4. Kumari I, Sudan M, Walia B, Chaudhary G. Zingiber officinale (Ginger): a review based upon its ayurvedic and modern therapeutic properties. Int J Curr Res 2021;13:16583-7.
5. Chauhan SA, Kaur AM, Vyas MA, Khatik GL. Comparison of antidiabetic and antioxidant activity of wild and cultivated variety of Rauwolfia serpentina. Asian J Pharm Clin Res 2017;10:404-6.
6. Chukwuma EC, Soladoye MO, Feyisola RT. Traditional medicine and the future of medicinal Plants in Nigeria. J Med Plants Studies 2015;3:23-9.
7. Lifongo LL, Simoben CV, Ntie Kang F, Babiaka SB, Judson PN. A bioactivity versus ethnobotanical survey of medicinal plants from Nigeria, West Africa. Nat Prod Bioprospecting 2014;4:1-9.
8. Ate? DA, Turgay O. Antimicrobial activities of various medicinal and commercial plant extracts. Turkish J Biol 2003;27:157-62.
9. Hamburger M, Hostettmann K. Bioactivity in plants: the link between phytochemistry and medicine. Phytochemistry 1991;30:3864-74.
10. Rai LK, Prasad P, Sharma E. Conservation threats to some important medicinal plants of the Sikkim Himalaya. Biological Conservation 2000;93:27-33.
11. Edeoga HO, Okwu DE, Mbaebie BO. Phytochemical constituents of some Nigerian medicinal plants. Afr J Biotechnol 2005;4:685-8.
12. Mann J. Secondary metabolism. Oxford University Press: London; 1978. p. 154.
13. Shanmugam MK, Lee JH, Chai EZ, Kanchi MM, Kar S, Arfuso F, et al. Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds. Seminars Cancer Biol 2016;40:35-47.
14. Cragg GM, Newman DJ. Natural product drug discovery in the next millennium. Pharm Biol 2001;39(Suppl):8-17.
15. Gontijo VS, de Souza TC, Rosa IA, Soares MG, da Silva MA, Vilegas W, et al. Isolation and evaluation of the antioxidant activity of phenolic constituents of the Garcinia brasiliensis epicarp. Food Chem 2012;132:1230-5.
16. Piccinelli AL, Cuesta Rubio O, Chica MB, Mahmood N, Pagano B, Pavone M, et al. Structural revision of clusianone and 7-epi-clusianone and anti-HIV activity of polyisoprenylated benzophenones. Tetrahedron 2005;61:8206-11.
17. Teh SS, Cheng Lian Ee G, Mah SH, Lim YM, Rahmani M. Mesua beccariana (Clusiaceae), a source of potential anti-cancer lead compounds in drug discovery. Molecules 2012;17:10791-800.
18. Asif M, Shafaei A, Jafari SF, Mohamed SK, Ezzat MO, Majid AS, et al. Isoledene from Mesua ferrea oleo-gum resin induces apoptosis in HCT 116 cells through ROS-mediated modulation of multiple proteins in the apoptotic pathways: a mechanistic study. Toxicol Lett 2016;257:84-96.
19. Bhide MB, Naik PV, Joshi RS. Bull. Haffkine Inst 1977;5:27-30.
20. Jain SR, Jain MR. Effect of some common essential oils on pathogenic fungi. Plant Med; 1973.
21. Rahman SM, Shabnom S, Quader MA, Hossain MA. Phytochemical study on the ethylacetate extract of the leaves of Mesua ferrea linn. Ind J Chem 2008;8:242-4.
22. Nurdin R, Osman N, Khalid K, Sukari MA. Development of microwave system for extraction of essential oils from Mesua ferrea L. leaves and jasminum sambac flowers. In: International RF and Microwave Conference; 2006. p. 243-6.
23. Rahman SM, Shabnom S, Quader MA, Hossain MA. Phytochemical study on the ethylacetate extract of the leaves of Mesua ferrea linn. Ind J Chem 2008;8:242-4.
24. Subramanyam Raju M, Subba Rao NV. Chemical study of the stamens of Mesua ferrea linn. J Res Imagerie Med 1977;12:124-6.
25. Subramanyam Raju M, Subba Rao NV. Fatty acid composition of nahor (Mesua ferrea Linn) seed oil. J Res Imagerie Med 1977;12:97-9.
26. Banerjee R, Choudhary AR. Mesua ferrea: chemical constituents and biological activity. J Chem Soc Pakistan 1993;15:207-11.
27. Dennis TJ, Akshaya Kumar K. Constituents of Mesua ferrea-a review. Fitoterapia 1998;69:291-304.
28. Sannd R, Bansal P, Bajwa RMS, Acharya MV. Folk medicine of patiala for Arsha (piles). J Ayurveda Health 2004;56:525-9.
29. Palani V, Senthilkumaran RK, Govindasamy S. Biochemical evaluation of antitumor effect of muthu marunthu (a herbal formulation) on experimental fibrosarcoma in rats. J Ethnopharmacol 1999;65:257-65.
30. Konwer D, Baruah K. Refining of the crude oil obtained from Mesua ferrea L. seeds. Chem Ind 1984. p. 413-4.
31. Kallappa M, Hosamani, Savita S, Ganjihal. Unique occurrence of unusual fatty acids in ochrocarpus africanus seed oil. Ind Crop Prod 2003;18:111-6.
32. Lim TK. Edible medicinal and non-medicinal plants. Dordrecht, The Netherlands: Springer; 2012.
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Published
15-07-2021
How to Cite
THAKUR, S., H. KAURAV, and G. CHAUDHARY. “MESUA FERREA LINN. (NAGKESAR): A POTENT ANTIMICROBIAL PLANT SPECIES”. International Journal of Current Pharmaceutical Research, vol. 13, no. 4, July 2021, pp. 6-13, doi:10.22159/ijcpr.2021v13i4.42734.
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Review Article(s)
