• BHOOMIKA RAVI Department of Microbiology, School of Life Sciences, Jss Academy of Higher Education and Research, S. S. Nagara, Mysoru, Karnataka, India
  • TALLURI RAMESHWARI K. R. Department of Microbiology, School of Life Sciences, Jss Academy of Higher Education and Research, S. S. Nagara, Mysoru, Karnataka, India
  • SUMANA K. Department of Microbiology, School of Life Sciences, Jss Academy of Higher Education and Research, S. S. Nagara, Mysoru, Karnataka, India



Antibiotic, Staphylococci, Susceptibility


Urinary tract infection (UTI) is one of the most common health problems among pregnant women and the reason for morbidity during pregnancy in worldwide, most of them in developing countries. The causative agents include Escherichia coli, Klebsiella species, Staphylococcus aureus, Staphylococci, Proteusmirabilis, Enterococcus species, Pseudomonas aeruginosa, Enterobacter species, streptococci, and Citrobacter species. Risk factors in pregnant women is more in urinary tract infection (UTI). This current research aimed that which drug is resistance for pathogenic bacteria and their resistance gene patterns in pregnant women. The altogether predominance of urinary tract infections in pregnant women is approximately 13-18% overall. Gram-positive and gram-negative both bacteria were isolated. Which shows gram-negative bacteria (85%) and gram-positive bacteria were only 15%. E. coliis the most predominant bacteria among the study. And the antimicrobial susceptibility patters of these isolates showed high resistance towards nitrofurantoin, ciprofloxacin, and gentamycin. More sensitive towards amoxiclav, cefuroxime, etc., Pregnant women with Asymptomatic UTI consider E. coli, Klebsiella pneumonia, Proteus mirabilis, Pseudomonas aeruginosa, Acinetobacter baumannii, Staphylococcus arlettae, Enterococcus faecalis and showed resistance to most drugs. The frequent appearance of isolates from urine sample along with their resistance capability tests. The antibiotics can be prescribed based on side effect to prevent pregnant women in case of empirical treatment. In order to overcome the problem of UTI in pregnant women many researches are going on, currently, the drug resistant of UTI is leading to the new technologies and identification method of drug-resistant UTI helps to overcome the infection.


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Hussein EF, Ameen JA, Yassen SH. Study the antibiotics activity against Escherichia coli isolated from urine samples of pregnant women with urinary tract infection. Int J Pharm Res. 2021 Jan;13(1).

Said A, El-Gamal MS, Abu-Elghait M, Salem SS. Isolation, identification and antibiotic susceptibility pattern of urinary tract infection bacterial isolates [lett]. Appl Nano Biosci. 2021;1.

Sabir S, Ahmad Anjum A, Ijaz T, Asad Ali M, Ur Rehman Khan M, Nawaz M. Isolation and antibiotic susceptibility of E. coli from urinary tract infections in a tertiary care hospital. Pak J Med Sci. 2014 Mar;30(2):389-92. doi: 10.12669/pjms.302.4289, PMID 24772149.

Ovalle A, Levancini M. Urinary tract infections in pregnancy. Curr Opin Urol. 2001 Jan 1;11(1):55-9. doi: 10.1097/00042307-200101000-00008, PMID 11148747.

Kalinderi K, Delkos D, Kalinderis M, Athanasiadis A, Kalogiannidis I. Urinary tract infection during pregnancy: current concepts on a common multifaceted problem. J Obstet Gynaecol. 2018 May 19;38(4):448-53. doi: 10.1080/01443615.2017.1370579, PMID 29402148.

Glaser AP, Schaeffer AJ. Urinary tract infection and bacteriuria in pregnancy. Urol Clin North Am. 2015 Nov 1;42(4):547-60. doi: 10.1016/j.ucl.2015.05.004, PMID 26475951.

Ghouri F, Hollywood A, Ryan K. Urinary tract infections and antibiotic use in pregnancy– qualitative analysis of online forum content. BMC Pregnancy Childbirth. 2019 Dec;19(1):289. doi: 10.1186/s12884-019-2451-z, PMID 31409404.

Saha S, Nayak S, Bhattacharyya I, Saha S, Mandal AK, Chakraborty S. Understanding the patterns of antibiotic susceptibility of bacteria causing urinary tract infection in West Bengal, India. Front Microbiol. 2014 Sep 18;5:463. doi: 10.3389/fmicb.2014.00463, PMID 25278932.

Beckford Ball J. Management of suspected bacterial urinary tract infection. Nurs Times. Nursing Times. 2006 Sep 1;102(36):25-6. PMID 16986589.

Hernandez Hernandez D, Padilla Fernandez B, Ortega Gonzalez MY, Castro Diaz DM. Recurrent urinary tract infections and asymptomatic bacteriuria in adults. Curr Bladder Dysfunct Rep. 2022;17(1):1-12. doi: 10.1007/s11884-021-00638-z, PMID 34868442.

Sibi G, Kumari P, Kabungulundabungi N. Antibiotic sensitivity pattern from pregnant women with urinary tract infection in Bangalore, India. Asian Pac J Trop Med. 2014 Sep 1;7S1:S116-20. doi: 10.1016/S1995-7645(14)60216-9, PMID 25312104.

Nitica RP, Gica N, Gica C, Ciobanu AM, Peltecu G, Cimpoca-Raptis BA. Urinary tract infections in pregnancy. Ro J Med Pract. 2021;16(S3):40-4. doi: 10.37897/RJMP.2021.S3.9.

Delzell JE, Lefevre ML. Urinary tract infections during pregnancy. Am Fam Physician. 2000 Feb 1;61(3):713-21. PMID 10695584.

Lee AC, Quaiyum MA, Mullany LC, Mitra DK, Labrique A, Ahmed P. Screening and treatment of maternal genitourinary tract infections in early pregnancy to prevent preterm birth in rural Sylhet, Bangladesh: a cluster randomized trial. BMC Pregnancy Childbirth. 2015 Dec;15(1):326. doi: 10.1186/s12884-015-0724-8, PMID 26643558.

Ranjan A, Sridhar STK, Matta N, Chokkakula S, Ansari RK. Prevalence of UTI among pregnant women and its complications in newborns. Indian J Pharm Pract. 2017 Jan;10(1):45-9. doi: 10.5530/ijopp.10.1.10.

Jazayeri MA, Irajian GR. Asymptomatic bacteriuria and symptomatic urinary tract infections in pregnancy. ESCI. 2008;38:50-7.

Haider G, Zehra N, Munir AA, Haider A. Risk factors of urinary tract infection in pregnancy. J Pak Med Assoc. 2010 Mar 1;60(3):213-6. PMID 20225781.

Lee AC, Mullany LC, Koffi AK, Rafiqullah I, Khanam R, Folger LV. Urinary tract infections in pregnancy in a rural population of Bangladesh: population-based prevalence, risk factors, etiology, and antibiotic resistance. BMC Pregnancy Childbirth. 2019;20(1):1. doi: 10.1186/s12884-019-2665-0, PMID 31892316.

Akhand A, Karicheri R. Describing the major pathogens causing UTI among patients, the prevalence of UTI and establish susceptibility pattern of antimicrobial resistance. Eur J Mol Clin Med. 2022;9(3).

Weinstein MP, Lewis JS. The clinical and laboratory standards institute subcommittee on antimicrobial susceptibility testing: background, organization, functions, and processes. J Clin Microbiol. 2020 Feb 24;58(3):e01864-19. doi: 10.1128/JCM.01864-19, PMID 31915289.

Patel JB, Tenover FC, Turnidge JD, Jorgensen JH. Susceptibility test methods: dilution and disk diffusion methods. In: Manual of clinical microbiology. 10th ed. American Society of Microbiology; 2011 Jan 1. p. 1122-43.

Barnett BJ, Stephens DS. Urinary tract infection: an overview. Am J Med Sci. 1997 Oct 1;314(4):245-9. doi: 10.1097/00000441-199710000-00007, PMID 9332263.

Smith JW, Segal M. Urinary tract infection in men-an internist’s viewpoint. Infection. 1994 Jan;22(1) Suppl 1:S31-4. doi: 10.1007/BF01716036, PMID 8050789.

Podschun R, Sievers D, Fischer A, Ullmann U. Serotypes, hemagglutinins, siderophore synthesis, and serum resistance of Klebsiella isolates causing human urinary tract infections. J Infect Dis. 1993 Dec 1;168(6):1415-21. doi: 10.1093/infdis/168.6.1415, PMID 7902383.

Plos K, Connell H, Jodal U, Marklund BI, Marild S, Wettergren B. Intestinal carriage of P fimbriated Escherichia coli and the susceptibility to urinary tract infection in young children. J Infect Dis. 1995 Mar 1;171(3):625-31. doi: 10.1093/infdis/171.3.625, PMID 7876609.

Connell I, Agace W, Klemm P, Schembri M, Marild S, Svanborg C. Type 1 fimbrial expression enhances Escherichia coli virulence for the urinary tract. Proc Natl Acad Sci USA. 1996 Sep 3;93(18):9827-32. doi: 10.1073/pnas.93.18.9827, PMID 8790416.

Hooton TM, Winter C, Tiu F, Stamm WE. Association of acute cystitis with the stage of the menstrual cycle in young women. Clin Infect Dis. 1996 Sep 1;23(3):635-6. doi: 10.1093/clinids/23.3.635, PMID 8879792.

Ouslander JG, Greengold B, Chen S. External catheter use and urinary tract infections among incontinent male nursing home patients. J Am Geriatr Soc. 1987 Dec;35(12):1063-70. doi: 10.1111/j.1532-5415.1987.tb04922.x, PMID 3680838.

Barnett BJ, Stephens DS. Urinary tract infection: an overview. Am J Med Sci. 1997 Oct 1;314(4):245-9. doi: 10.1097/00000441-199710000-00007, PMID 9332263.

Baldassarre JS, Kaye D. Special problems of urinary tract infection in the elderly. Med Clin North Am. 1991 Mar 1;75(2):375-90. doi: 10.1016/s0025-7125(16)30460-6, PMID 1996040.

Abrutyn E, Mossey J, Berlin JA, Boscia J, Levison M, Pitsakis P. Does asymptomatic bacteriuria predict mortality and does antimicrobial treatment reduce mortality in elderly ambulatory women? Ann Intern Med. 1994 May 15;120(10):827-33. doi: 10.7326/0003-4819-120-10-199405150-00003, PMID 7818631.

Stamm WE, Hooton TM. Management of urinary tract infections in adults. N Engl J Med. 1993 Oct 28;329(18):1328-34. doi: 10.1056/NEJM199310283291808, PMID 8413414.

Kaye D. Dipsticks for diagnosis of urinary tract infection in the nursing home. JAMA. 1995 Sep 1;274(11):868. doi: 10.1001/jama.274.11.868, PMID 7674489.



How to Cite

RAVI, B., T. R. K. R., and S. K. “BACTERIA ASSOCIATED WITH URINARY TRACT INFECTION IN PREGNANT WOMEN WITH OVERVIEW OF THEIR ANTIBIOTIC SUSCEPTIBILITY TESTS”. International Journal of Current Pharmaceutical Research, vol. 14, no. 4, July 2022, pp. 10-15, doi:10.22159/ijcpr.2022v14i4.2007.



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