• BHARANI DHARAN SETHURAMAN Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur, India
  • LAKSHMI PRABHA CHANDRASEKAR Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur, India
  • MANIKANDAN SUBRAMANI Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur, India
  • ASWATHY KARANATH ANILKUMAR IIISM, SRM Institute of Science and Technology, Kattankulathur, India
  • MUNUSWAMY-RAMANUJAM GANESH IIISM, SRM Institute of Science and Technology, Kattankulathur, India
  • SIVAKAMI MOHANDOS Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur, India




Green synthesis, Trachyspermum ammi, Bismuth oxide, Biological activity


Objective: This work is mainly focused to determine the antibacterial activity of the green synthesized Bi2O3 nanoparticles against the bacterial strains, Staphylococcus aureus and Escherichia coli using resazurin as indicator.

Methods: Bismuth oxide nanoparticles were synthesized from the precursor bismuth nitrate [Bi (NO3)3.5H20] by using trachyspermum ammi (ajwain) seed extract. To carry out these works, the synthesized Bi2O3 NPs undergone characterizations and were confirmed by UV-Vis, FT-IR, XRD, SEM and EDAX, TGA-DTA and DLS. Biological activity was done using a well diffusion method.

Results: Bi2O3 NP's has been tested against bacteria (S. aureus and E. coli) in wells and shows blue colour, indicating bacterial growth inhibition in a dose-dependent manner for different concentrations.

Conclusion: The biological studies were done with one gram-positive and one gram-negative bacteria to show the inhibiting efficiency. The synthesized bismuth oxide nanoparticles showed good anti-bacterial activity (different concentrations) against S. aureus and E. coli.


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How to Cite

SETHURAMAN, B. D., L. P. CHANDRASEKAR, M. SUBRAMANI, A. K. ANILKUMAR, M.-R. GANESH, and S. MOHANDOS. “AJWAIN SEEDS AS CAPPING AGENT FOR Bi2O3 NANOFLAKES: SYNTHESIS AND GROWTH INHIBITING EFFICIENCY OF BACTERIA”. International Journal of Current Pharmaceutical Research, vol. 15, no. 3, May 2023, pp. 19-25, doi:10.22159/ijcpr.2023v15i3.2099.



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