STUDY OF CARRIER RATE OF COVID-19 AMONG PARACLINICAL and GOVERNMENT DEGREE COLLEGE STUDENTS AT A TERTIARY CARE HOSPITAL, SRIKAKULAM

Authors

  • M. BHARATHI Department of Microbiology, Government Medical College, Srikakulam-532001, Andhra Pradesh, India
  • S. S. VIJAYASRI BADAMPUDI Department of Microbiology, Government Medical College, Srikakulam-532001, Andhra Pradesh, India

DOI:

https://doi.org/10.22159/ijcpr.2023v15i5.3046

Keywords:

Asymptomatic carriers, Covid-19, Healthcare settings, RT-PCR, SARS-CoV-2, Vaccination status

Abstract

Objective: Role of nosocomial transmission of SARS-CoV-2 is becoming increasingly recognized, with several reports indicating that the number of asymptomatic cases can be several-fold higher than the reported symptomatic cases. With this background, we did study to know the carrier rate of Covid-19 in healthy, asymptomatic adolescents and young adults and to compare it among students exposed and not exposed to healthcare settings.

Methods: Nasopharyngeal swabs were collected from 200 students: DMLT trainees as test group and Degree college students as control group, in equal number. Samples were subjected to RT-PCR test for Covid-19, by extracting RNA by using the "HimediaHiGenoMB" kit and doing PCR by using "Meril Covid-19 one-step RT-PCR kit.

Results: All the participants are in the age group of 18-22 y and Female students constituted 73.5%. All participants in the test group were vaccinated (100%), but only 34% in control group (94.4% of female and 64.28% of male students had two doses). One-fourth of male students were not vaccinated at all in control group. None of the control group were positive for covid-19, but four male students (16%) and 11 female students (14.6%) were positive in test group.

Conclusion: Healthcare professionals (HCPs) are at risk of getting infection of Covid 19, because of their exposure to asymptomatic or, pre-symptomatic or to the Covid-19 positive persons before the diagnosis being made. Vaccine coverage in male students was less when compared to female students. Hundred percent vaccine coverage was seen in HCPs.

Downloads

Download data is not yet available.

References

Sastry AS, Bhat S. Chapter 67. Essentials of medical microbiology. 3rd ed. section 8, Published by Jaypee Brothers Medical Publishers; 2021. p. 660-72.

Lai CC, Liu YH, Wang CY, Wang YH, Hsueh SC, Yen MY. Asymptomatic carrier state, acute respiratory disease, and pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): facts and myths. J Microbiol Immunol Infect. 2020 Jun;53(3):404-12. doi: 10.1016/j.jmii.2020.02.012, PMID 32173241.

Johansson MA, Quandelacy TM, Kada S, Prasad PV, Steele M, Brooks JT. SARS-CoV-2 transmission from people without Covid-19 symptoms. JAMA Netw Open. 2021;4(1):e2035057. doi: 10.1001/jamanetworkopen.2020.35057, PMID 33410879.

Zhoua F, Lib J, Luc M, Linlu Maa YP, Zhub XLX, Hub C. “Tracing asymptomatic SARS-CoV-2 carriers among 3674 hospital staff: a cross-sectional survey. E Clinical Medicine. 2020;26:100510. doi: 10.1016/j.eclinm.2020.100510.

Rivett L, Sridhar S, Sparkes D, Routledge M, Jones NK, Forrest S. Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in Covid-19 transmission. eLife. 2020;9:e58728. doi: 10.7554/eLife.58728, PMID 32392129.

Zhu N, Zhang D, Wang W, Li X, Yang B, Song J. A novel coronavirus from patients with pneumonia in China. N Engl J Med. 2020;382(8):727-33. doi: 10.1056/NEJMoa2001017, PMID 31978945.

Lu HZ, Stratton CW, Tang YW. Outbreak of pneumonia of unknown etiology in Wuhan, China: the mystery and the miracle. J Med Virol. 2020;92(4):401-2. doi: 10.1002/jmv.25678, PMID 31950516.

Duan S, Zhou M, Zhang W, Shen J, Qi R, Qin X. Seroprevalence and asymptomatic carrier status of SARS-CoV-2 in Wuhan City and other places of China. PLOS Negl Trop Dis. 2021;15(1):e0008975. doi: 10.1371/journal.pntd.0008975. PMID 33411805.

Oran DP, Topol EJ. Prevalence of asymptomatic SARS-CoV-2 infection. Ann Intern Med. 2020 Sep;173(5):362-7. doi: 10.7326/M20-3012.

Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–Infected Pneumonia in Wuhan, China. JAMA. 2020;323(11):1061-9. doi: 10.1001/jama.2020.1585, PMID 32031570.

Chatterjee S, Sarkar A, Karmakar M, Chatterjee S, Paul R. SEIRD model to study the asymptomatic growth during Covid-19 pandemic in India. Indian J Phys Proc Indian Assoc Cultiv Sci. 2021 Dec;95(12):2575-87. doi: 10.1007/s12648-020-01928-8, PMID 33250600.

Caturano V, Manti B, Carbone F, Lasorsa VA, Colicchio R, Capasso M. Estimating asymptomatic SARS-CoV-2 infections in a geographic area of low disease incidence. BMC Infect Dis. 2021;21(1):350. doi: 10.1186/s12879-021-06054-2, PMID 33853532.

Ma Q, Liu J, Liu Q, Kang L, Liu R, Jing W. Global percentage of asymptomatic SARS-CoV-2 infections among the tested population and individuals with confirmed Covid-19 diagnosis: a systematic review and meta-analysis. JAMA Netw Open. 2021;4(12):e2137257. doi: 10.1001/jamanetworkopen.2021.37257, PMID 34905008.

McIntosh K. Epidemiology, virology, and prevention. Up to date Covid-19: updated. Editors Martin S Hirsch, MD. And Allyson Bloom. MD; 15 Aug 2022.

McMichael TM, Currie DW, Clark S, Pogosjans S, Kay M, Schwartz NG. Epidemiology of Covid-19 in a long-term care facility in king county, Washington. N Engl J Med. 2020;382(21):2005-11. doi: 10.1056/NEJMoa2005412, PMID 32220208.

He X, Lau EHY, Wu P, Deng X, Wang J, Hao X. Temporal dynamics in viral shedding and transmissibility of Covid-19. Nat Med. 2020;26(5):672-5. doi: 10.1038/s41591-020-0869-5, PMID 32296168.

Syangtan G, Bista S, Dawadi P, Rayamajhee B, Shrestha LB, Tuladhar R. Asymptomatic SARS-CoV-2 carriers: a systematic review and meta-analysis. Front Public Health. 2020;8:587374. doi: 10.3389/fpubh.2020.587374, PMID 33553089.

Pillai S, Manimehalai M. A descriptive study to assess the knowledge regarding Covid-19 vaccine among students in selected nursing college at Tamil Nadu. Int J Immunol Nurs. 2022;8(1).

Qiao S, Friedman DB, Tam CC, Zeng C, Li X. Covid-19 vaccine acceptance among college students in South Carolina: do information sources and trust in information matter? J Am Coll Health. 2020 Dec 4. doi: 10.1101/2020.12.02.20242982

Xiong Y, Zhao Y, Zhang T, Wang Q, Liu JA. Factors associated with the vaccination behavior among Covid-19 vaccine hesitant college students in Wuhan, China: A survey based on social psychological dimension. Front Public Health. 2022 May 11;10:865571. doi: 10.3389/fpubh.2022.865571, PMID 35646770.

Nizam A, Iqbal T, Mashood H, El Nebrisi E. Analyzing Covid-19 vaccine hesitancy among university students in UAE: A cross-sectional study. Dubai Medical Journal 2022.

Gala D, Parrill A, Patel K, Rafi I, Nader G, Zhao R. Factors impacting Covid-19 vaccination intention among medical students. Hum Vaccin Immunother. 2022;18(1):2025733. doi: 10.1080/21645515.2022.2025733. PMID 35113775.

Ulbrichtova R, Svihrova V, Svihra J. Prevalence of Covid-19 vaccination among medical students: a systematic review and meta-analysis. Int J Environ Res Public Health. 2022;19(7):4072. doi: 10.3390/ijerph19074072. PMID 35409755.

Neunhoffer AT, Gibilaro J, Wagner A, Soeder J, Rebholz B, Blumenstock G. Factors associated with the Covid-19 vaccination status of higher education students: results of an online cross-sectional survey at six universities in Southwestern Germany. Vaccines. 2022;10(9):1433. doi: 10.3390/vaccines10091433. PMID 36146511.

Published

15-09-2023

How to Cite

BHARATHI, M., and S. S. V. BADAMPUDI. “STUDY OF CARRIER RATE OF COVID-19 AMONG PARACLINICAL and GOVERNMENT DEGREE COLLEGE STUDENTS AT A TERTIARY CARE HOSPITAL, SRIKAKULAM”. International Journal of Current Pharmaceutical Research, vol. 15, no. 5, Sept. 2023, pp. 50-53, doi:10.22159/ijcpr.2023v15i5.3046.

Issue

Section

Original Article(s)