COMPARATIVE ANALYSIS OF COVID-19 PATIENTS DURING DELTA AND OMICRON WAVES OF COVID-19 PANDEMIC: AN EXPERIENCE FROM RURAL TERTIARY CARE HOSPITAL IN NORTH INDIA

SAUMYA SHUKLA; SAURABH PANDEY; PRIYANKA RAI; VANDANA UPADHYAY; VINOD KUMAR MAURYA

doi:10.22159/ijcpr.2024v16i6.6014

Authors

SAUMYA SHUKLA Department of Microbiology, Maharshi Vashishtha Autonomous State Medical College, Basti, Uttar Pradesh, India
SAURABH PANDEY Department of Medicine, Baba Raghav Das Medical College, Gorakhpur, UP, India
PRIYANKA RAI Department of Pathology, Maharshi Deoraha Baba Autonomous State Medical College, Deoria, Uttar Pradesh, India https://orcid.org/0000-0002-1458-9579
VANDANA UPADHYAY 1. Department of Microbiology, Maharshi Vashishtha Autonomous State Medical College, Basti, Uttar Pradesh, India
VINOD KUMAR MAURYA Department of Microbiology, Maharshi Vashishtha Autonomous State Medical College, Basti, Uttar Pradesh, India https://orcid.org/0000-0001-9746-8299

DOI:

https://doi.org/10.22159/ijcpr.2024v16i6.6014

Keywords:

Clinical, COVID-19, Delta variant, Omicron variant, Outcome, Rural India

Abstract

Objective: In this study, an effort has been made to find out possible clinical parameters that may have played role in differences in the disease outcome in the delta and omicron waves.

Methods: This is a retrospective observational study conducted at a rural tertiary care center of North India. We recorded sociodemographic and clinicopathological parameters of the admitted patients during delta and omicron waves in India. The outcome measures were demographic, baseline clinical, disease severity, ICU admissions and hospital mortality.

Results: In our study, 1731 patients were tested positive for SARS-CoV-2, out of which 16 patients were admitted during the omicron wave and 878 admissions during the delta wave. In delta wave, the ratio of male to female was 1:2 and in omicron wave, it was 1:3. There were 271 deaths in delta wave and 2 deaths in omicron wave. A significantly lower number of admissions were noted during omicron wave (p<0.001). Patients without previous history of COVID-19 and unvaccinated status had significantly higher admission (p<0.001). The admission rate among comorbid patients was also significantly low in the omicron wave (p<0.001). 251 patients had one or more comorbidities and were mostly in severe (13.4%) or critical (88.4%) conditions in delta wave while among 13 comorbid patients in omicron wave, 7.7% were in severe and 15.4% were in critical condition.

Conclusion: The hospital admissions were very low in comparison to delta wave. During delta wave, the degree of severity and number of deaths were also very high.

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