• Shalini Sivadasan Karpagam College of Pharmacy, Karpagam University, Coimbatore, India 641032
  • Mohan Sellappan Karpagam College of Pharmacy, Karpagam University, Coimbatore, India 641032


Knowledge, Attitude, Nursing students, Adverse drug reactions, Reporting, Pharmacovigilance


Objective: This study was conducted to evaluate the knowledge and attitude towards pharmacovigilance and adverse drug reactions reporting among the nursing students in a private university, Malaysia.

Methods: The survey was carried out using a pre-validated questionnaire that included demographics details and 29 survey items to evaluate the participant's knowledge and perception on adverse drug reactions and pharmacovigilance. The questionnaire was distributed to the participants (n=32) pre-final and final year nursing students after their informed consent.

Results: The study results found that, there was no significant difference noticed between the mean knowledge score on ADRs reporting and pharmacovigilance of pre-final year and final year students (p>0.05). The overall mean score on knowledge was found to be 12.31. The study also observed that mean score on attitude in pre-final year and final year students were 13.24 and 16.00 respectively. There was no significant difference observed between the mean score on the perception of pre-final year and final year students (p>0.05). The overall mean score for perception on ADRs reporting and pharmacovigilance was found to be 15.06.

Conclusion: The results show that nursing students who participated in the study were only moderately aware of pharmacovigilance and adverse drug reaction reporting. However, they had expressed the positive attitude towards pharmacovigilance and ADRs reporting. As future health care professionals, they are expected to have sound knowledge and positive attitude towards pharmacovigilance activities. Their knowledge and attitude would exert a strong influence on ADRs reporting.


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Ramesh M, Pundit J, Parthasarathy G. Adverse drug reactions in a South Indian teaching hospital-their severity and cost involved. Pharmacoepidemiol Drug Saf 2003;12:687-92.

World Health Organization. International drug monitoring: The role of national centres. Report of a WHO meeting. World Health Organ Tech Rep Ser 1972;498:1-25.

Kessler DA. Introducing Med Watch, using FDA form 3500, a new approach to reporting medication and device adverse effects and product problems. JAMA 1993;269:2765-8.

Lee A, Thomas SHL. Adverse drug reactions. In: Walker R and Edward C. Clinical Pharmacy and Therapeutics, 3rd ed. US; Churchill Livingstone; 2003. p. 33-46.

Classen DC, Pestotnik SL, Evans RS, Lloyd JF, Burke JP. Adverse drug events in hospitalized patients. JAMA 1997;277Suppl 4:301-6.

WHO. The importance of pharmacovigilance. World Health Organization, Geneva; 2002. p. 146-57.

Phatak A, Nagari BG. Safety of medicines. Pharm Times 2003;35:19-21.

Shuka SS, Bina G, Pandey R, Rao SP, Singh V, Amber V. Importance of Pharmacovigilance in Indian Pharmaceutical Industry. Asian J Res Pharm Sci 2012;2:4-8.

Von Laue NC, Schwappach DL, Koeck CM. The epidemiology of preventable adverse drug events: a review of literature. Wien Klin Wochenschr 2003;115 Suppl 12:407-15.

Wu WK, Pantaleo N. Evaluation of outpatient adverse drug reactions leading to hospitalization. Am J Health Syst Pharm 2003;60(Suppl 3):253-9.

Aziz Z, Siang TC, Badarudin NS. Reporting of adverse drug reactions: predictors of under-reporting in Malaysia. Pharmacoepidemiol Drug Saf 2007;16:223-8.

Olsson S. The need for pharmacovigilance. In: Gupta SK. Pharmacology and Therapeutics in the New Millennium. New Delhi: Narosa Publishing House; 2001. p. 502-8.

Oshikoya KA, Awobusuyi J. Perceptions of doctors to adverse drug reaction reporting in a teaching hospital in Lagos, Nigeria. BMC Clin Pharmacol 2009;9:14.

Green CF, Mottram DR, Rowe PH, Pirmohamed M. Attitudes and knowledge of hospital pharmacists to adverse drug reaction reporting. Br J Clin Pharmacol 2001;51:81-6.

Subish P, Izham M, Mishra P. Evaluation of the knowledge, attitude and practices on adverse drug reactions and pharmacovigilance among healthcare professionals in a Nepalese hospital: a preliminary study. Int J Pharm 2007;6 Suppl 1:1-5.

Hazell L, Shakir SA. Under-reporting of adverse drug reactions: a systematic review. Drug Saf 2006;29:385-96.

Moride Y, Haramburu F, Requejo AA, Begaud B. Under reporting of adverse drug reactions in general practice. Br J Clin Pharmacol 1997;43 Suppl 2:177-81.

Ahmad SR. Adverse drug event monitoring at the Food and Drug Administration. J Gen Int Med 2003;18:57-60.

Malaysian adverse drug reactions advisory committee. Available from:http://portal.bpfk.gov.my/index.cfm?menuid=24&parentid=16(2012).

Haq ASM. Pharmacovigilance initiatives in Malaysia. Drug Inf J 2003;57:143-8.

Rehan HS, Sah RK, Chopra D. Comparison of knowledge, attitude and practices of resident doctors and nurses on adverse drug reaction monitoring and reporting in a tertiary care hospital. Indian J Pharmacol 2012;44 Suppl 6:699-703.

John LJ, Arifulla M, Cheriathu JJ, Sreedharan J. Reporting of adverse drug reactions: a study among Clinicians. J Appl Pharm Sci 2012;2 Suppl 6:135-9.

Amrita P, Singh SP. Status of spontaneous reporting of adverse drug reaction by physicians in Delhi. Indian J Pharm Prac 2011;4 Suppl 2:29-36.

Subish P, Ibrahim MI, Mishra P. Health professionals' knowledge, attitude and practices towards pharmacovigilance in Nepal. Pharm Prac 2011;9 Suppl 4:228-35.

Hajebi G, Mortazavi SA, Salamzadeh J, Zian Aed. A Survey of knowledge, attitude and practice of nurses towards pharmacovigilance in Taleqani Hospital. Iran J Pharm Res 2010;9 Suppl 2:199-206.

Gavaza P, Bui B. Pharmacy students’ attitudes toward reporting serious adverse drug events. Am J Pharm Edu 2012;76 Suppl 10:194.

Upadhyaya P, Seth V, Moghe VV, Sharma M, Ahmed M. Knowledge of adverse drug reaction reporting in first year postgraduate doctors in a medical college. Dove Press J: Ther Clin Risk Manage 2012;8:307-12.

Elkalmi RM, Hassali MA, Ibrahim MIM, Widodo RT, Efan QMA, Hali MA. Pharmacy students’ knowledge and perceptions about pharmacovigilance in Malaysian public universities. Am J Pharm Edu 2011;75 Suppl 5:1-8.

Sivadasan S, Yuong NY, Chyi NG, Ching ALS, Nazer Ali A, Veerasamy R, et al. Knowledge and perception towardspharmacovigilance andadverse drug reaction reporting among medicine and pharmacy students. World J Pharm Pharm Sci 2014;3 Suppl 3: 652-76.

Rajesh R, Vidyasagar S, Varma DM. An Educational intervention to assess knowledge attitude practice of pharmacovigilance among health care professionals in an Indian tertiary care teaching hospital. Int J Pharm Tech Res 2011;3 Suppl 2: 78-92.

Muraraiah S, Rajarathna K, Sreedhar D, Basavalingu D. A questionnaire study to assess the knowledge, attitude and practice of pharmacovigilance in a paediatric tertiary care centre. J Chem Pharm Res 2011;3 Suppl 6:416-22.

Desai CK, Iyer G, Shah S, Dikshit RK. An evaluation of knowledge, attitude, and practice of adverse drug reaction reporting among prescribers at a tertiary care hospital. Perspect Clin Res 2011;2 Suppl 4:129-36.

Chatterjee S, Lyle N, Ghosh S. A survey of the knowledge, attitude and practice of adverse drug reaction reporting by clinicians in eastern India. Drug Saf 2006;29:641-2.

Hanafi S, Torkamandi H, Hayatshahi A, Gholami K, Javadi M. Knowledge, attitudes and practice of nurses regarding adverse drug reaction reporting. Iran J Nursing Midwifery Res 2012;17 Suppl 1:21-5.

Sencan N, Altinkaynak M, Ferah I, Ozyildirim A, Ceylan EM, Clark PM. The knowledge and attitudes of physicians and nurses toward adverse event reporting and the effect of pharmacovigilance training: A hospital experience. Hacettepe University J Faculty Pharm 2010;30 Suppl 1:25-40.

Kharkar M, Bowalekar S. Knowledge, attitude and perception/practices (KAP) of medical practitioners in India towards adverse drug reaction (ADR) reporting. Perspect Clin Res 2012;3 Suppl 3:90-4.

Khalili H, Mohebbi N, Hendoiee N, Keshtkar AA, Khavidaki. Improvement of knowledge, attitude and perception of healthcare workers about ADR, a pre-and post-clinical pharmacists' interventional study. BMJ Open 2012;2 Suppl 1:e000367.

Gupta P, Udupa A. Adverse drug reaction reporting and pharmacovigilance: Knowledge, attitudes and perceptions amongst resident doctors. J Pharm Sci Res 2011;3 Suppl 2:1064-9.

John LJ, Arifulla M, Cheriathu JJ, Sreedharan J. Reporting of adverse drug reactions: an exploratory study among nurses in a teaching hospital, Ajman, United Arab Emirates. DARU J Pharm Sci 2012;20 Suppl 44:1-6.



How to Cite

Sivadasan, S., and M. Sellappan. “A STUDY ON THE AWARENESS AND ATTITUDE TOWARDS PHARMACOVIGILANCE AND ADVERSE DRUG REACTION REPORTING AMONG NURSING STUDENTS IN A PRIVATE UNIVERSITY, MALAYSIA”. International Journal of Current Pharmaceutical Research, vol. 7, no. 1, Jan. 2015, pp. 84-89, https://journals.innovareacademics.in/index.php/ijcpr/article/view/5344.



Original Article(s)