METHODS OF THE ESTIMATED TWO-PARAMETER LINEAR REGRESSION MODELSFOR DIAGNOSIS OF BRONCHIAL ASTHMA SEVERITY IN CHILDREN
DOI:
https://doi.org/10.22159/ijms.2021.v9i1.40408Keywords:
asthma, child, regression modelAbstract
Objectives: Prognostication of bronchial asthma severity in children by means of two-parameter regression models building.
Methods: A clinical study of 70 children with bronchial asthma diagnosis of 6 to 18 years old was done.142 factors were analyzed and a degree of relationship among them was revealed. Single-factor regression models were used during preliminary experimental data processing.
Results: The correlation connection between the value observed and the factors under research was revealed. The method of two-parameter linear models with a fair accuracy was developed.
Conclusion: The suggested method of approximate two-parameter linear regression models can be used for preliminary analysis of medical research data where the value observed depends on a big number of loosely connected factors.
References
Global Strategy for Asthma Management and Prevention. 2018. Available from: https://ginasthma.org/2018-ginareport-global-strategy-for-asthma-management-andprevention/Global atlas of asthma.
Asthma. Who.int. 2019.Available from:http://www.who.int/ru/news-room/factsheets/detail/asthma/.
ISAAC - The International Study of Asthma and Allergies in Childhood. Isaac.auckland.ac.nz. 2019. Available from: http://isaac.auckland.ac.nz/.
Sritipsukho P, Satdhabudha A, Nanthapisal S. Effect of allergic rhinitis and asthma on the quality of life in young Thai adolescents. Asian Pac J Allergy Immunol. 2015;33(3):222–6.
Oliveira-Santos S, Motta-Franco J, Barreto I, Solé D, Gurgel R. Asthma in adolescents--Prevalence trends and associated factors in northeast Brazil. AllergolImmunopathol (Madr). 2015;43(5):429–35.
Montella S, Baraldi E, Cazzato S, Aralla R, Berardi M, Brunetti L et al. Severe asthma features in children: a case–control online survey. Ital J Pediatr. 2016; 42: 9.
Foster J, McDonald V, Guo M, Reddel H. “I have lost in every facet of my life”: the hidden burden of severe asthma. European Respiratory Journal. 2017;50(3):1700765.
Fleming L, Murray C, Bansal A, Hashimoto S, Bisgaard H, Bush A et al. The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts. European Respiratory Journal. 2015;46(5):1322–1333.
Andersson C, Adams A, Nagakumar P, Bossley C, Gupta A, De Vries D et al. Intraepithelial neutrophils in pediatric severe asthma are associated with better lung function. J Allergy Clin Immunol. 2017;139:1819–1829.
Fajt M, Wenzel S. Asthma phenotypes and the use of biologic medications in asthma and allergic disease: The next steps toward personalized care. Journal of Allergy and Clinical Immunology. 2015;135(2):29–9310.
Salo P, Arbes S, Jaramillo R, Calatroni A, Weir C, Sever M et al. Prevalence of allergic sensitization in the United States: Results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006. Journal of Allergy and Clinical Immunology. 2014;134(2):350–359.
Gough H, Grabenhenrich L, Reich A, Eckers N, Nitsche O, Schramm D et al. Allergic multi morbidity of asthma, rhinitis and eczema over 20 years in the German birth cohort MAS. Pediatric Allergy and Immunology. 2015;26(5):431–437.
Garcia-Aymerich J, Benet M, Saeys Y, Pinart M, Basagaña X, Smit H et al. Phenotyping asthma, rhinitis and eczema in MeDALL population-based birth cohorts: an allergic comorbidity cluster. Allergy. 2015;70(8):973–984.
Pols D, Bohnen A, Nielen M, Korevaar J, Bindels P. Risks for co morbidity in children with atopic disorders: an observational study in Dutch general practices. BMJ Open. 2017; 7(11): e018091.
Pinart M, Benet M, Annesi-Maesano I, von Berg A, Berdel D, Carlsen K. Co morbidity of eczema, rhinitis, and asthma in IgEsensitised and non-IgE-sensitised children in MeDALL: a population-based cohort study. Lancet Respir Med. 2014;2(2):131–134.
Jacob L, Keil T, Kostev K. Comorbid disorders associated with asthma in children in Germany - National analysis of pediatric primary care data. Pediatr Allergy Immunol. 2016;27:861– 866.
Amin P, Levin L, Epstein T, Ryan P, LeMasters G, Khurana Hershey G et al. Optimum Predictors of Childhood Asthma: Persistent Wheeze or the Asthma Predictive Index? The Journal of Allergy and Clinical Immunology: In Practice. 2014;2(6):709–715.e2.
Puranik S, Forno E, Bush A, Celedón J. Predicting severe asthma exacerbations in children.American Journal of Respiratory and Critical Care Medicine. 2017;195(7):854– 859.
Kozhyna O, PihnastyiO. Data Structure of Clinical Research. Human Health & Disease.2019;3(9):71-79.
Campo P, Rodríguez F, Sánchez-García S, Barranco P, Quirce S, Pérez-Francés C et al. Phenotypes and endotypes of uncontrolled severe asthma: new treatments. J InvestigAllergol Clin Immunol. 2013;23(2):76–88.
Lodge C, Zaloumis S, Lowe A, Gurrin L, Matheson M, Axelrad C et al. Early-life risk factors for childhood wheeze phenotypes in a high-risk birth cohort. J Pediatr. 2014;164:289–294.22.
Chung K, Wenzel S, Brozek J, Bush A, Castro M, Sterk P et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J. 2014;43:343–373.
Cook J, Beresford F, Fainardi V, Hall P, Housley G, Jamalzadeh A et al. Managing the paediatric patient with refractory asthma: a multidisciplinary approach. J. Asthma Allergy 2017; 10: 17– 30.
Chong S, Chew. Epidemiology of allergic rhinitis and associated risk factors in Asia. World Allergy Organization Journal. 2018; 11:17.
Cazzoletti L, Ferrari M, Olivieri M, Verlato G, Antonicelli L, Bono R et al. The gender, age and risk factor distribution differs in self-reported allergic and non-allergic rhinitis: a cross-sectional population-based study. Allergy, Asthma & Clinical Immunology. 2015;11(1).
Imhof K, Probst E, Seifert B, Regenass S, Schmid-Grendelmeier P. Ash pollen allergy: reliable detection of sensitization on the basis of IgE to Ole e 1. Allergo Journal International. 2014;23(3):78–83.
Hill D, Spergel J. The atopic march: critical evidence and clinical relevance. Ann Allergy Asthma Immunol. 2018; 120(2): 131–137.
Salo P, Arbes S, Jaramillo R, Calatroni A, Weir C, Sever M et al. Prevalence of allergic sensitization in the United States: Results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006. Journal of Allergy and Clinical Immunology. 2014;134(2):350–359.
Gough H, Grabenhenrich L, Reich A, Eckers N, Nitsche O, Schramm D et al. Allergic multimorbidity of asthma, rhinitis and eczema over 20 years in the German birth cohort MAS. Pediatric Allergy and Immunology. 2015;26(5):431–437.
Garcia-Aymerich J, Benet M, Saeys Y, Pinart M, Basagaña X, Smit H et al. Phenotyping asthma, rhinitis and eczema in MeDALL population-based birth cohorts: an allergic comorbidity cluster. Allergy. 2015;70(8):973–984.
Pols D, Bohnen A, Nielen M, Korevaar J, Bindels P. Risks for comorbidity in children with atopic disorders: an observational study in Dutch general practices. BMJ Open. 2017; 7(11): e018091.
Pinart M, Benet M, Annesi-Maesano I, von Berg A, Berdel D, Carlsen K. Comorbidity of eczema, rhinitis, and asthma in IgEsensitised and non-IgE-sensitised children in MeDALL: a population-based cohort study. Lancet Respir Med. 2014;2(2):131–134.
Corren J, Manning B.E., Thompson S.F., Strom B.L., Rhinitis therapy and the prevention of hospital care for asthma: a case-control study. J Allergy Clin Immunol. 2004; 113: 415-419
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