STUDY OF THE EFFECT OF OBESITY ON IMMUNE CELLS ACTIVITY AND CARDIOVASCULAR DISEASE RISK IN EL-OUED (ALGERIA) WOMEN

IKRAM ACHCHI; SAMIR DEROUICHE

doi:10.22159/ijms.2021.v9i3.41189

Authors

IKRAM ACHCHI Department of Cellular and Molecular Biology, Faculty of Natural and Life Sciences, El-Oued University, El Oued 39000, El Oued, Algeria.
SAMIR DEROUICHE Department of Cellular and Molecular Biology, Faculty of Natural and Life Sciences, El-Oued University, El Oued 39000, El Oued, Algeria.

DOI:

https://doi.org/10.22159/ijms.2021.v9i3.41189

Keywords:

Obesity, Immune cells, Biochemical markers, Women

Abstract

Objective: This study was conducted to find out the effect of obesity on immune cells activity and some biochemical markers in women.

Methods: The experimentation is carried out on 30 voluntary individuals were divided into two groups; 15 women with obesity (Body Mass Index [BMI]>30) were selected, On the other hand, we took 15 witnesses (BMI<30). All the volunteers were subjected to estimate the lipid profile, biochemical, and hematological parameters.

Results: Results obtained show that there was a significant increase of blood glucose (p<0.05), triglyceride (p<0.05) and uric acid (p<0.001) and no significant change of other biochemical markers in obese people’s group when compared to the control subjects. In addition, the hematological results demonstrated that there was a significant decrease (p<0.05) of lymphocytes, hemoglobin, hematocrit, and mean corpuscular volume levels (p<0.01) in women with obesity compared to the controls.

Conclusion: Our study reveals that the obesity may be induce the sever alteration in lipid profile which cause the cardiovascular risk for this population. In addition, the obesity causes a remarkable change in some biochemical markers and blood constituent’s anemia or other metabolic disorder in the body.

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