SYNTHETIC PRODUCT ILLEGALLY SOLD IN BRAZIL AS A MEDICINAL HERBAL PRODUCT: CHEMICAL ANALYSIS AND THE PATIENTS MEDICATION EXPERIENCE

Thays Santos Mendonca; Rayza Martins Miranda; Carlos Alexandre Carollo; Simone De Araujo Medina Mendonca; JOAO MAXIMO DE SIQUEIRA

doi:10.22159/ijpps.2016v8i10.13160

Authors

Thays Santos Mendonca Campus Centro Oeste Dona Lindu, Universidade Federal De SÃ£o JoÃ£o Del Rei, Brazil
Rayza Martins Miranda Campus Centro Oeste Dona Lindu, Universidade Federal De SÃ£o JoÃ£o Del Rei, Brazil
Carlos Alexandre Carollo LaboratÃ³rio de Produtos Naturais e Espectrometria de Massas, Universidade Federal de Mato Grosso do Sul, Brazil
Simone De Araujo Medina Mendonca Departmento de FarmÃ¡cia Social, Faculdade de FarmÃ¡cia, Universidade Federal de Minas Gerais, Brazil
JOAO MAXIMO DE SIQUEIRA Campus Centro Oeste Dona Lindu, Universidade Federal De SÃ£o JoÃ£o Del Rei, Brazil

DOI:

https://doi.org/10.22159/ijpps.2016v8i10.13160

Keywords:

Herbal medicine adulteration, Chemical analysis, Medication experience, Qualitative research

Abstract

Objective: To analyze a product illegally sold as herbal medicine acquired and used by a patient and to understand the reasons that led the patient to use this product. Methods: The chemical analysis was performed by thin layer chromatography (TLC) and mass spectrometry (MS) analysis with a direct infusion with a Bruker Daltonics UltroTOF-Q, in positive mode. A qualitative interview was conducted with the patient. The data obtained were submitted to thematic analysis. Results: Chemical analysis confirmed the presence of piroxicam and orphenadrine, and the complete absence of a natural product. The qualitative study revealed three themes: previous experience with the disease and the use of medicines, feelings about the care provided by health professionals, and the patient's solution.

Conclusion: The commercial availability of this kind of product raises concerns about safety and demonstrates the necessity for more intensive surveillance by health authorities. In addition, the present study showed the need for a patient-centered practice and the understanding of medication experience to provide effective care to patients who use medicines to preserve them from unsafe products.

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