• Pooja Verma A. School of Pharmaceutical Sciences, IFTM University, Moradabad, India.
  • Lal V. K. School of Pharmaceutical Sciences, IFTM University, Moradabad, India.


Eye disorders, Boerhaavia diffusa (BD), Ayurveda, Ocular, Ophthalmia


This review aims to provide comprehensive affirmations on the phytochemical and pharmacological aspects of Boerhaavia Diffusa, Nyctaginaceae also known as Punarnavaâ€. It possesses a vast ethnomedical history and represents a phytochemical reservoir of heuristic medicinal value. It is one of the oldest oriental medicines mentioned in Ayurveda as potential remedy for various ailments. The whole plant is rich in glycosides, steroids, flavonoids and also contains various polyphenolic compounds. Many pharmacological studies have demonstrated the ability of its antioxidant, ophthalmic,anti-inflammatory, spermatogenic, aphrodisiac, immunostimulant, hepatoprotective, antiasthamatic, supporting its traditional uses. In this review article, we have focused our interest on phytochemistry,enlistment of phytochemicals, responsible for therapeutic values,traditional uses and its reported pharmacological properties.


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Biswas NR, Gupta SK, Das GK, Kumar N, Mongre PK, Haldar D, et al. Evaluation of ophtha care eye drops – a herbal formulation in the management of various ophthalmic disorders. J Phytotherapy Res 2001;15:1-4.

Seth RK, Khanna M, Chaudhary M, Singh S, Sarin JPS. Estimation of punarnavosides, a new antifibrinolyticcompound from Boerhaavia diffusa. J Indian Drugs 1986;583-4.

Nandini N, Shiddamallayya N. Diversity of medicinal plants flora of old Mysore district, Karnataka, India. J Indo American J of Pharm Res 2013;3(8):6248-58.

Soni N, Lal VK, Agrawal S, Verma H.Golden eye grass-a magical remedy by nature. Int J of Pharm Sci and Res 2012;3(8):2407-20.

Meena AK, Pal B, Singh B, Yadav AK., Singh U, Kaur R, et al. A review on cataract and its herbal treatments. J Drug Invention Today 2010;2(2):178-81.

Murti K, Mayank AP, Lambole V. Pharmacological Properties of Boerhaavia diffusa-a review. Int J of Pharm Sci Rev and Res 2010;5(2):107-10.

Bhowmik D, Sampath KP, Srivastava S, Paswan S, Dutta AS. Traditional Indian herbs punarnava and its medicinalimportance. J of Pharm and Phytochemistry 2012;1(1):59-65.

Agarwal RR, Dutt SS. Chemical examination ofpunarnava or Boerhaavia diffusaLinn, Isolation of analkaloid punarnavine. J Chem Abstr 1936;30 (2):35-85.

Basu NK, Lal SB, Sharma SN. Investigations on Indianmedicinal plants. Q J Pharm Pharmacol 1947;20:38-42.

Surange SR, Pendse GS. Pharmacognostic study ofroots of Boerhaavia diffusaWild. (Punarnava). J ResIndian Med 1972;7:1-5.

Mahesh AR, Kumar H, Ranganath MK, Raviraj AD. Detail study on Boerhaavia diffusa plant for its medicinal importance-A Review. Res J of Pharm Sci 2012;1(1):28-36.

Awasthi LP, Verma HN. Boerhaavia Diffusa – A wild herb with potent biological and antimicrobial properties, J Department of Plant Pathology Narendra Dev University of Agriculture and Technology:Kumarganj, Faizabad, Uttar Pradesh, India.

Thakur RS, Puri HS, Husain A. Major Medicinal Plants of India. Central Institute of Medicinaland Aromatic Plants (CIMAP), Lucknow:Uttar Pradesh, India;1989.p.116.

Bhansali RR, Kumar A, Arya HC. In-vitro induction of adventitious shoots on stem explants ofBoerhaavia diffusaL. J Current Sci 1978;47:551-2.

Shrivastava N, Padhya MA. Punarnavine†profile in the regenerated roots of Boerhaavia diffusaL. from leaf segments. J Current Sci 1995;68:653-56.

Meena AK, Niranjan US, Yadav AK, Ajit K, Singh B, Kiran, Rao MM. A Quality Assessment of Boerhaavia Diffusa Linn. commonly known as ‘Punarnava’ plant. Int J of Pharmacognosy and Phytochemical Res 2010;2(1):25-8.

Santhosha D, Ramesh A, Prasad MS, Kumar DS, Kumar BP, Dhanalakshmi.Punarnava-a review, Res J of Pharm Biological and Chemical Sci 2011;2(4):427-35.

Singh A, Eno EE, Quraish MA.Boerhavia Diffusa (Punarnava) root extract as green corrosion inhibitor for mild steel in hydrochloric acid solution:theoretical and electrochemical studies. Int J of Electrochemical Sci 2012;7:8659-75.

Jain M, Kapadia R, Ravirajsinh, Navalsinh J, Thounaojam CM, Devkar RV, Mishra SH. Traditional uses, phytochemistry and pharmacology of Tecomellaundulata-A review. Asian Pacific J of Tropical Biomedicine 2012;S1918-S23.

Gupta RBL, Singh S, Dayal Y. Effectof Punarnava on the visual acuity andrefractive errors. Indian J of Medical Res 1962;50:428-34.

Riaz H, Raza SA, Hussain S, Mahmood S, Malik F.An overview of ethnopharmacological properties of Boerhaavia diffusa. African J of Pharmacy and Pharmacology 2014;8(2):49-58.

Rawat AK, Mehrotra S, Tripathi SC, Shome U. Hepatoprotective activity of Boerhavia diffusaL. roots-a popular Indian ethnomedicin. J of Ethno pharmacology 1997;56.

Sahu AN,Damiki L, Nilanjan G, Dubey S. Phytopharmacological review of Boerhaavia Diffusa Linn. (Punarnava). J Pharmacognosy Rev–Supplement 2008;2(4):14-22.

Kirtikar KR, Basu BD, Boerhaavia diffusa. Indian medicinal plants. J Lalit Mohan Basu Publications Allahabad, India 1956;2045-8.

Anonymous, Astanghradayam, Hindi Commentary, vol. II, Chaukhambha Publications, New Delhi. Explained Use of local plants for eye disorders 1991;135-43.

Anonymous, An appraisal of tribal folk medicines.Hindi Commentary, Central council for research in Ayurveda & siddha. Ministry of health and family welfare. Government of India, First edition. New Delhi:1999;151-3.

Rajpoot K, Mishra RN. Boerhaavia Diffusa Roots (Punarnava mool) – Review as rasayan (rejuvenator / antiaging). Int J of Res in Pharm and Biol Sci 2011;2(4):1451-60.

Ramachandra YL, Ashajyothi C, Rai PS. In-Vitro antibacterial potential of Boerhaavia diffusa. Int J of Adv in Pharmacy, Biology and Chemistry 2012;1(3):420-3.

Nalamolu RK, Boini KM, Nammi S. Effect of chronic administration of Boerhaavia diffusaLinn. leaf extract on experimental diabetes in rats. Tropical J of Pharm Res 2004;3(1):305-9.

Pari L, Satheesh MA. Antidiabetic activity of Boerhaavia diffusaL. Effect on hepatic key enzymes in experimental diabetes. J of Ethno pharmacology 2004;91:109-13.

Hiruma-Lima CA, Gracioso JS, Bighetti EJ. The juice of fresh leaves of Boerhaavia diffusaL. (Nyctaginaceaeae). J Ethnopharmacol 2000;71(1-2):267-74.

Sreeja S, Sreeja S. An in-vitro study on anti-proliferative and anti-estrogenic effects of Boerhaaviadiffusa L. extracts. J of Ethnopharmacology 1923;126:221-5.

Bhalla TN, Gupta MB, Sheth PK and Bhargava KP. Antiinflammatory activity of Boerhaavia diffusa. Indian J of Physiology and Pharmacology 1968;12:37.

Kulkarni SK. Handbook of Experimental Pharmacology. J Vallabh Prakashan 2003;3:128-31.

Oladele GM, Ode OJ, Ogunbodede MA. Evaluation of anti-inflammatory and membrane stabilizing effects of aqueous root extract of Boerhavia Diffusa Linn. In Rats. Int J of Applied Biology and Pharm Technology 2011;2(3):84-8.

Adesina SK. Anticonvulsant properties of the roots of Boerhaavia diffusa. Quarterly J of Crude Drug Res 1979;17:84-6.

Sumanth M, Mustafa SS. Antistress, adoptogenic and immunopotentiating activity roots of Boerhaavia diffusain mice. Int J Pharmacol 2007;3:416-20.

Goyal BM, Bansal P, Gupta V, Kumar S, Singh R, Maithani M. Pharmacological potential of Boerhaaviadiffusa:An Overview. Int J of Pharm Sci and Drug Res 2010;2(1):17-22.

Chauhan CK, Joshi MJ, Vaidya ADB. Growth Inhibition of Struvite Crystals in the Presence of Herbal Extract Boerhaavia diffusaLinn. American J of Infectious Diseases 2009;5(3):177-86.

Jagetia GC, Rao SK, Baliga MS, Babu KS. The Evaluation of Nitric Oxide Scavenging Activity of Certain Herbal Formulations in vitro:A Preliminary Study. J Phytotherapy Res 2004;18:561-5.

Sasi Kala M, Vijay SK, Gauthaman K. Relevance of the use of Alternative Medicine for Bronchial Asthma:A review. J Young Pharm 2009;1(2):184-9.

Shukla N, Sangwan NS, Misra HO, Sangwan RS. Genetic diversity analysis in Boerhaavia diffusaL. of different geographic locations in India using RAPD markers. J Genetic Resources and Crop Evolution 2003;50:587-601.



How to Cite

Verma A., P., and L. V. K. “PUNARNAVA-A NATURAL REMEDY BY AYURVEDA”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 6, no. 8, Aug. 2014, pp. 1-6, https://journals.innovareacademics.in/index.php/ijpps/article/view/1326.



Review Article(s)