A case of lacunar infarction of brain and hypertension associated with prolonged use of “SUKHI”
Keywords:
Adverse drug reaction, OCPs, Brain infarction, Self-medications, SukhiAbstract
we are presenting a case of young married lady who visited to our hospital with ,Hypertension for last 4 years & had complain of scalp pain , head reeling & vertigo for 3 years and was treated with antihypertensive ,multi-vitamins , Betahistine, without much benefit for her symptoms. Ultimately the case was found to be a case of Hypertension & lacunar infarct, which was possibly  due to long term, irrational, self medication of SUKHI†, an oral contraceptive pill.
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References
Safety Monitoring of Medicinal Products. Guidelines for setting up and running a Pharmacovigilance Centre. Uppsala Monitoring Centre - WHO Collaborating Centre for International Drug Monitoring, EQUUS, London, 2000.
European Commission. 2008. Strengthening Pharmacovigilance to Reduce Adverse Effects of Medicines. Available at http://ec.europa.eu/health/files/pharmacos/pharmpack_12_2008/memo_pharmacovigiliance_december_2008_en.pdf
Lazarou J. et al., 1998. Incidence of ADR in hospitalized patients: a meta-analysis of prospective studies. JAMA, 1998, 279 (15) 1000-5.
Moore N et al. Frequency and cost of serious adverse drug reactions in a department of general medicine. Br J ClinPharmacol 1998, 45(3), 301-308.
Imbs JL et al. Latrogenic medication: estimation of its prevalence in French public hospitals. Thèrapie, 1999, 54(1) 21-27.
World Health Organization: The role of the pharmacist in self-care and self-medication. Report of the 4th WHO consultative group on the role of the pharmacist.
Bradley C, Blenkinsopp A. Over the counter drugs: the future for self-medication. BMJ 1996; 312:835-837.
WHO Collaborative Study of Cardiovascular Disease
and Steroid Hormone Contraception, Ischaemic stroke and combined oral contraceptives: results of an international, multicentre, case-control study. Lancet. 1996;348498- 505
Heinemann LAJLewis MAThorogood MSpitzer WOGuggenmoos-Holzmann IBruppacher R Case-control study of oral contraceptives and risk of thromboembolic stroke: results from International Study on Oral Contraceptives and Health of Young Women. BMJ. 1997;3151502- 1504
Schwartz SMPettini DBSiscovick DS et al. Stroke and use of low-dose oral contraceptives in young women: a pooled analysis of two US studies. Stroke.1998;292277- 2284