EFFECTIVENESS OF SPIRULINA MOUTHWASH ON REDUCTION OF DENTAL PLAQUE AND GINGIVITIS: A CLINICAL STUDY

Authors

  • Radhika Maniyar Department of Public Health Dentistry, M R Ambedkar Dental College and Hospital, Bangalore
  • Umashankar G. K. Department of Public Health Dentistry, M R Ambedkar Dental College and Hospital, Bangalore

DOI:

https://doi.org/10.22159/ijpps.2017v9i7.18415

Keywords:

Gingivitis, Herbal mouthrinse, Phycocyanin, Spirulina

Abstract

Objective: The present study evaluated the effectiveness of Spirulina mouthwash on the reduction of dental plaque and gingivitis.

Methods: A single-blind clinical trial was conducted among thirty patient's aged 18-40 y visiting dental college and hospital in Bangalore city. Mouthwash was prepared using 0.5% Spirulina. Intervention protocol consisted of instructing the patients to rinse with 10 ml of mouthwash for 1 minute twice daily for 7 d. Plaque index and Gingival index were used to assess the variables at the baseline and after the intervention. The perception of the individual subjects with regard to the use of mouthwash was assessed using 10 cm long visual analog scale (VAS). Statistical analysis was carried out using Wilcoxon signed rank test for mean pre and post plaque and gingival scores respectively. Descriptive statistics was performed for VAS questionnaire

Results: The results showed a highly significant difference (p<0.001) between the mean plaque scores at the baseline (2.16±0.34) and at the follow up (1.27±0.46). The mean gingival scores at the baseline (1.86±0.38) and at the follow-up (1.05±0.43) also showed a highly significant difference (p<0.001). Regarding the Visual Analog Scale, the mean values of 5 or greater than suggested the responses to be favourable as the values were reflected

Conclusion: The study showed that Spirulina mouthwash resulted in significant reduction in dental plaque and gingivitis. Also, the mouthwash was convenient to use without any adverse effects. Hence, the use of herbal mouth rinses such as Spirulina should be supported.

Downloads

Download data is not yet available.

References

PE Petersen, D Bourgeois, H Ogawa, S Estupinan-Day, C Ndiaye. The global burden of oral diseases and risks to oral health. Bull W H O 2005;83:661-9.

Socransky S, Haffajee A. Dental biofilms: difficult therapeutic targets. Periodontol 2002;28:12-55.

Gupta D, Nayan S, Tippanawar HK. Are herbal mouthwash efficacious over chlorhexidine on the dental plaque? Pharmacogn Res 2015;7:277-81.

Al Habashneh R, Qubain TG, Alsalman W, Khader Y. The effect of listerine mouthwash on dental plaque, gingival inflammation and C-reactive protein (CRP). Dentistry 2014;4:191-5.

DePaola LG, Overholser CD, Meiller TF, Minah GE, Niehaus C. Chemotherapeutic inhibition of supragingival dental plaque and gingivitis development. J Clin Periodontol 1989;16:311-5.

Baker K. Mouthrinses in the prevention and treatment of periodontal disease. Curr Opinion Periodontol 1992;89:96.

Ciancio SG. Use of mouth rinses for professional indications. J Clin Periodontol 1988;15:520-3.

Silness J, Löe H. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 1964;22:121-35.

Löe H. The gingival index, the plaque index and the retention index systems. J Periodontol 1967;38 Suppl:610.

Marchetti E, Mummolo S, Di Mattia J, Casalena F, Di Martino S, Mattei A, et al. Efficacy of essential oil mouthwash with and without alcohol: a 3-day plaque accumulation model. Trials 2011;12:262.

Sharma R, Hebbal M, Ankola AV, Murugaboopathy V, Shetty SJ. Effect of two herbal types of mouthwash on the gingival health of school children. J Traditional Complementary Med 2014;4:272-8.

Ku CS, Yang Y, Park Y, Lee J. Health benefits of blue-green algae: prevention of cardiovascular disease and nonalcoholic fatty liver disease. J Med Food 2013;16:103-11.

Sudha SS, Karthic R, Rengaramunjan J Athulya. Antimicrobial activity of spirulina platensis and aphanothece sp. on selected clinical bacterial isolates and its antioxidant activity. South As J Biol Sci 2011;1:87-98.

G Usharani, G Srinivasan, S Sivasakthi, P Saranraj. Antimicrobial activity of spirulina platensis solvent extracts against pathogenic bacteria and fungi. Advan Biol Res 2015;9:292-8.

Robert Henrikson. Spirulina: health discoveries from the Source of life. Positive Health Online; 1998.

Méndez-Vilas A. Antimicrobial activity of aqueous and methanolic extracts from arthrospira maxima; 2011. p. 1267-71.

L Sujatha, T Lalitha Goverdhan. Antibacterial activity of green Seaweed on oral bacterial. Indian J Nat Prod Res 2012;3:328-33.

Lewis Oscar F, Nithya C, Bakkiyaraj D, Arunkumar M, Alharbi NS, Thajuddin N. Biofilm Inhibitory Effect of Spirulina platensis Extracts on Bacteria of Clinical Significance. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences;2015. p. 1-8.

Lee JC, Hou MF, Huang HW. Marine algal natural products with anti-oxidative, anti-inflammatory, and anti-cancer properties. Cancer Cell Int 2013;13:55.

Demidov AA, Mimuro M. Deconvolution of C-phycocyanin beta-84 and beta-155 chromophore absorption and fluorescence spectra of cyanobacterium Mastigocladus laminosus. Biophys J 1995;68:1500–6.

Datla P. The wonder molecule called phycocyanin. Chennai–India: Parry Nutraceuticals; 2011. Available from: http://www.valensa.com/images3/Phycocyanin_The% 20Wonder% 20Molecule.pdf. [Last accessed on 05 Feb 2017]

Araghizadeh N, Paknejad M, Alaeddini M, Minaii B, Abdollahi M, Khorasanie R. The efficacy and prophylactic characteristics of omega-3 fatty acids in experimental gingivitis in rats. Iran J Basic Med Sci 2014;17:87-92.

K Moorehead, B Capelli. 3rd edition. Spirulina nature’s superfood; 2011. p. 25-7.

Remirez D, Ledon N, Gonzalez R. Role of histamine in the inhibitory effects of phycocyanin in experimental models of allergic inflammatory response. Mediators Inflammation 2002;11:81-5.

MahenDra J, MahenDra L, Muthu J, John L, Romanos GE. Clinical effects of subgingivally delivered Spirulina gel in chronic periodontitis cases: a placebo-controlled clinical trial. J Clin Diagn Res 2013;7:2330.

Colla LM, Furlong EB, Costa JA. Antioxidant properties of Spirulina (Arthospira) platensis cultivated under different temperatures and nitrogen regimes. Braz Arch Biol Technol 2007;50:161-7.

Hirahashi T, Matsumoto M, Hazeki K, Saeki Y, Ui M, Seya T. Activation of the human innate immune system by spirulina: augmentation of interferon production and NK cytotoxicity by oral administration of hot water extract of Spirulina platensis. Int Immunopharmacol 2002;2:423-34.

Published

01-07-2017

How to Cite

Maniyar, R., and U. G. K. “EFFECTIVENESS OF SPIRULINA MOUTHWASH ON REDUCTION OF DENTAL PLAQUE AND GINGIVITIS: A CLINICAL STUDY”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 9, no. 7, July 2017, pp. 136-9, doi:10.22159/ijpps.2017v9i7.18415.

Issue

Section

Original Article(s)