PHARMACOLOGICALLY ACTIVE SAPONINS FROM THE GENUS ALBIZIA (FABACEAE)

Authors

  • Antony De Paula Barbosa Instituto de Pesquisas de Produtos Naturais, Centro de Ciencias da Saude, Universidade Federal do Rio de Janeiro, CEP 21941-971 Rio de Janeiro, Brasil.

Keywords:

Albizia, Saponins, Pharmacology properties

Abstract

Albizia species (Family – Fabaceae) are endemic in tropical America, Africa and Southeast Asia. Albizia lebbeck, Albizia julibrissin, Albizia gummifera, Albizia chinensis, Albizia adiathifolia and Albizia proceraare some importantly considered species in the traditional medicine. These species are used in folk medicine for the treatment of rheumatism, stomach ache, cough, diarrhea, wounds, anthelmentic and others. Saponins are the main compound present in species of this genus and showed many pharmacological properties as antioxidant, antidiabetic, anthelmentic, antibacterial, hepato protective, anti-inflammatory and cytotoxic. The present investigation reviews the main saponins pharmacologically active of species of the genus Albizia.

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References

Arce MLR, Gale SL, Maxted N. A taxonomic study of Albizia (Leguminosae: Mimosoidae: Ingeae) in Mexico and Central America. Analesdel Jardin Botánico Madrid 2008;65:255-305.

Sparg SG, Light ME, Staden JV. Biological activities and distribution of plant saponins. J Ethnopharmacol 2004;94:219-43.

Grade JT, Arble BL, Weladji RB, Damme PV. Anthelmintic efficacy and dose determination of Albizia anthelminticaagainst gastrointestinal nematodes in naturally infected Ugandan sheep. Vet Parasitol 2008;157:267-74.

Babu NP, Pandikumar P, Ignacimuthu S. Anti-inflammatory activity of Albizia lebbeck Benth, an ethnomedicinal plant, in acute and chronic animal models of inflammation. J Ethnopharmacol 2009;125:356-60.

Gupta RK, Siber GR. Adjuvants for human vaccines–current status, problems and future prospects. Vaccine 1995;14:1263-76.

Nurul IM, Mizuguchi H, Shahriar M, Venkatesh P, Maeyama K, Mukherjee M, et al. Albizia lebbeck suppresses histamine signaling by the inhibition of histamine H1 receptor and histidine decarboxylase gene transcriptions. Int Immunopharmacol 2011;11:1766-72.

Martínez M, De Pinto GL, Alvarez S, De Troconis NG, Ocando E, Rivas C. Composition and properties of Albizia lebbeck gum exu date. Biochem Syst Ecol 1995;23:843-8.

Zheng H, Wu Y, Ding J, Binion D, Fu W, Reardon R. Invasive Plants of Asian Origin Established in the United States and Their Natural Enemies, Vol. 1. United States Department of Agriculture Forest Service, FHTET; 2004. p. 15–8.

Zhang Z, Koike K, Jia Z, Nikaido T, Guo D, Zheng J. Triterpenoidal saponins from Gleditsiasinensis. Phytochem 1999;52:715-22.

Nehdi I. Characteristics, chemical composition and utilization of Albizia julibrisinseed oil. Ind Crops Prod 2011;33:30-4.

Higuchi H, Kinjo J, Nohara T. An arrhythmic-inducing glycoside from Albiziajulibrissin Durazz. IV. Chem Pharm Bull 1992;40:829–31.

Otani H, Matsumori M, Hosono A. Purification and some properties of a milk clotting protease from the young seeds of Albizia julibrissin. Anim Sci Technol 1991;62:424–32.

Han L, Pan G, Wang Y, Song X, Gao X, Ma B, Kang L. Rapid profiling and identification of triterpenoid saponins in crude extracts from Albizia julibrissin Durazz. byultra high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry. J Pharm Biomed Anal 2011;55:996-1009.

Zheng L, Zheng J, Zhang Q, Wang B, Zhao Y, Wu L. Three new oleanane triterpenoid saponins acetylated with monoterpenoid acid from Albizia julibrissin. Fitoterapia 2010;81:859-63.

Zou K, Tong WY, Liang H, Cui JR, Tu GZ, Zhao YY, et al. Diastereoisomeric saponins from Albizia julibrissin. Carbohydr Res 2005;340:1329-34.

Zheng L, Zheng J, Zhao Y, Wang B, Wu L, Liang H. Three anti-tumor saponins from Albizia julibrissin. Bioorg Med Chem Lett 2006;16:2765-8.

Debella A, Haslinger E, Schmid MG, Bucar F, Michl G, Abebe D, et al. Triterpenoid saponins and sapogenin lactones from Albizia gummifera. Phytochem 2000;53:885-92.

Liu R, Ma SG, Liu YX, Yu SS, Chen XG, Zhang JJ. Albizosides D and E, two new cytotoxic triterpene saponins from Albizia chinensis. Carbohydrate Res 2010;345:1877-81.

Haddad M, Larens V, Lacaille-Dubois MA. Induction of apoptosis in a leukemia cell line by triterpene saponins from Albizia adianthifolia. Bioorg Med Chem 2004;12:4725-34.

Miyase T, Melek FR, Ghaly NS, Warashina T, El-Kady M, Nabil M. Echinocystic acid 3, 16-O-bisglycosides from Albiziaprocera. Phytochem 2010;71:1375-80.

Published

01-11-2014

How to Cite

Barbosa, A. D. P. “PHARMACOLOGICALLY ACTIVE SAPONINS FROM THE GENUS ALBIZIA (FABACEAE)”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 6, no. 11, Nov. 2014, pp. 32-36, https://journals.innovareacademics.in/index.php/ijpps/article/view/1881.

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Section

Review Article(s)