PLANT PROFILE, PHYTOCHEMISTRY AND PHARMACOLOGY OF ARGEMONE MEXICANA LINN.A REVIEW
Keywords:
Plant Profile, Phytochemistry, Pharmacology, Biological activity, Argemone mexicana, Toxicity, Safety EvaluationAbstract
Argemonemexicanais extensively used as traditional medicine for the treatment of numerous diseases. Various parts of the plant were extensively used in Ayurveda, Siddha, Unani and Homeopathic medicines.It is reported to have antimicrobial activity, wound healing property, larvicidal and chemosterilant activity, neÂmaticidal and allelopathic potential, antimalarial, antibacterial and antifungal, molluscicidal, anticancer, hepatoprotective, anti-HIV and neuropharmacological activity. Chemical investigations of this plant have revealed the presence of alkaloids, amino acids, phenolics and fatty acids. A. mexicana has shown promise as an effective bio-control agent. The present review includes the detailed exploration of traditional uses, phytochemical and pharmacological properties and actions of whole plant extract reported so far.
Downloads
References
Kamboj VP. Herbal medicine. J Cur Sc 2000;78(1):35-9.
Dalvil RR. Sanguinarine. It’s potential, as a liver toxic alkaloid present in the seeds of Argemone mexicana. J Cell Mol Life Sci 1985;41(1):77-8.
Sood NN, Mahipal S, Sachdev, Mohan M, Gupta SK and Sachdev HPS. Epidemic dropsy following transcutaneous absorption of Argemone mexicana oil. J Trans R Soc Trop Med Hyg 1985;79(4):510-2.
Izzo AA, Carlo D, Biscardi G, Fusco D, Mascolo R, Borreli N, Capasso F, Fasulo F and Autore MP. Biological screening of Italian medicinal plants for antibacterial activity. J Phytother 1995;9:281-6.
Dash GK and Murthy PN. Evaluation of Argemone mexicana leaves for wound healing activity. J Nat Prod Plant Resour 2011;1(1):46-56.
Sakthivadivel M and Thilagavathy D. Larvicidal and chemosteri¬lant activity of the acetone fraction of petroleum ether extract from Ar¬gemone mexicana seed. J Biores Tech 2003;89(2):213-6.
Shaukat SS, Siddiqui IA, Khan GH and Zaki MJ. Nemati¬cidal and allelopathic potential of Argemone mexicana, a tropical weed. J Plant Soil 2002;245:230-47.
Adolfo Andrade-Cetto, Michael Heinrich. Mexican plants with hypoglycemic effect used in the treatment of diabetes. J of Ethnopharmacology2005;99:325-48.
Hussain SF, Nakkady S, Khan L, Shamma M. Oxyhydrastinine, an isoquinoline alkaloid from the Papaveraceae. J Phytochemistry 1983;22:319-20.
Nakkady S, Shamma M. Studies on the chemical constituents of Argemone mexicana. Egypt J Pharm Sci 1988;29:53-61.
Dinda B, Bandyopadhyay MJ. Free amino acids of Argemone mexicana. J Indian Chem Soc 1986;63:934-6.
Harborne JB, Williams CA. Flavonoids in the seeds of Argemone mexicana:a reappraisal. J Phytochemistry 1983;22:1520-21.
Gunstone FD, Holliday JA, Scrimgeour CM. Fatty acids, part 51. The long-chain Oxo acids (argemonic acids) in Argemone mexicana seed oil. J Chemistry and Physics of Lipids 1977;20(4):331-5.
Kenneth W Bentley. β-Phenylethylamines and the isoquinoline alkaloids. J Nat Prod Rep 2001;18:148-70.
Merlin L Willcox, Bertrand Graz, Jacques Falquet, Oumar Sidibé, Mathieu Forster, Drissa Diallo. Argemone mexicana decoction for the treatment of uncomplicated falciparum malaria. J Trans R Soc Trop Med Hyg 2007;101(12):1190-8.
Bertrand Graz, Merlin L, Willcox, Chiaka Diakite, Jacques Falquet, Florent Dackuo, Oumar Sidibe, Sergio Giani, Drissa Diallo. Argemone mexicana decoction versus artesunateamodiaquine for the management of malaria in Mali:policy and public-health implications. J Trans R Soc Trop Med Hyg 2010;104(1):33-41.
Sushma Singh, DK Singh. Molluscicidal activity of Abrus precatoriusand Argemone mexicana. J Chemosphere 1999;38(14):3319-28.
Singh S, SinghDK. Effect of active molluscicidal components of Abrus precatorius, Argemone mexicana and Nerium indicum on certain enzymes in the nervous tissue ofLymnaea acuminata. J Sci I R Iran 2000;11(3):187-94.
Bhattacharjee I, Chatterjee SK, Chatterjee S, Chandra G. Antibacterial potentiality of Argemone mexicana solvent extracts against some pathogenic bacteria. J Mem Inst Oswaldo Cruz 2006;101(6):645-8.
SatishS, MohanaDC, Raghavendra MP, RaveeshaKA. Antifungal activity of some plant extracts against important seed borne pathogens of Aspergillus sp. J Agri Tech 2007;109-19.
Siddiqui IA, Shaukat SS, Khan GH, Zaki MJ. Evaluation of Argemone mexicana for control of root-infecting fungi in potato. J Phytopathol 2002;150:321-9.
Osho and T Adetunji. Antimicrobial activity of essential oil of Argemone mexicana. J of Med Plants Res 2010;4(1):019–022.
Das PK, Sethi R, Panda P, Pani SR. Hepatoprotective activity of plant Argemone mexicana against carbon tetrachloride (CCl4) induced hepatotoxicity in rats. Int J Pharm Res Dev 2009;8:1-20.
Chang Yuh-Chwen, Hsieh Pei-Wen, Chang Fang-Rong, Wu Ru-Rong, Liaw Chih-Chuang, Lee Kuo-Hsiung, Wu Yang-Chang. Two new protopines argemexicaines A and B and the anti-HIV alkaloid 6-acetonyldihydrochelerythrine from Formosan Argemone mexicana. J Planta Medica 2003;69(2):148-52.
Capasso A, Aquino R, Tommasi N De, Piacente S, Rastrelli L, Pizza C. Neuropharmacology activity of alkaloids from South American medicinal plants. J Curr Medi Chem-CNS agents 2002;2(1):1-15.
Chopra RN, Nayar SL, Chopra IC. Glossary of Indian medicinal plants. New Delhi:NISCOM, CSIR;1956. p. 23.
Albuquerque UP, Monteiro JM, Ramosa MA, Amorim ELC. Medicinal and magic plants from a public market in north eastern Brazil. J Ethnopharmacol 2007;110:76-91.
Makhija IK, Khamar D. Anti-snake venom properties of medicinal plants. J Der Pharmacia Letter 2010;2:399-411.
Minu V, Harsh V, Ravikant T, Paridhi J, Noopur S. Medicinal plants of Chhattisgarh with anti-snake venom property. Int J Curr Pharm Rev Res 2012;3:1-10.
Manjamalai A, Sardar Sathyajith singh R, Guruvayoorappan C and Berlin Grace VM. Analysis of phytochemical constituents and anti-microbial activity of some medicinal plants in Tamilnadu, India. Global J Biotechnol Biochem 2010;5(2):120-8.
Mohana DC, Satish S, Raveesha KA. Antibacterial evaluation of some plant extracts against some human pathogenic bacteria. J Advan Biol Res 2008;2(3-4):49-55.
Santosh Kumar Singh, Vidya Dhar Pandey, Aradhana Singh, Chandan Singh. Antibacterial activity of seed extracts of Argemone mexicana on some pathogenic bacterial strains. Afr J Biotechnol 2009;8(24):7077-81.
Satish Kumar Verma, Santosh Kumar Singh, Abhishek Mathur and Shivsharan Singh. In vitro cytotoxicity of Argemone mexicana against different human cancer cell lines. Int J Chem Environ Pharm Res 2010;1(1):37-9.
Shyam Prasad G, Dhanapal R. Antibacterial and antifungal activity of methanolic extract of Argemone mexicana leaves. Int J of Phytopharmacology 2010;1(2):64-7.
Perumal P, Sekar V, Rajesh V, Gandhimathi S, Sampathikumar R, Shuja Nazimudin KH. In vitro antioxidant activity of Argemone mexicana roots. Int J Pharm Tech Res 2010;2(2):1477-82.
Shahedur Rahman Md, Faizus Salehin Md, Abu Hena Mostofa Jamal Md, Anzana Parvin, Khasrul Alam Md. Antibacterial activity of Argemone mexicana against water borne microbes. Res J Med Plant 2011;5(5):621-6.
Das GK, Murthy PN. Evaluation of Argemone mexicana leaves for wound healing activity. J Nat Prod Plant Resour 2010;1(1):46-56.
Prusti AB, Mishra A. Interesting medico-botanical claims by Khouds of Nayagarh district of Orissa. J Plant Sci Res 2005;27(182):16-23.
Alagesaboopathi C:ethnomedicinal plants and their utilization by villagers in Kumaragiri hills of Salem district of Tamil Nadu, India. Afr J Tradit Complementary Altern Med 2009;6:222-7.
Bose BC, Vijayvargiya R, Saifi AQ, Sharma SK. Chemical and pharmacological studies on Argemonemexicana. J Pharm Sci 1963;52:1172-75.
Savithramma N, Sulochana Ch, Rao KN. Ethnobotanical survey of plants used to treat asthma in Andhra Pradesh, India. J Ethnopharmacol 2007;113:54-61.
Agra MF, Silva KN, BasÃlio IJLD, de Freitas PF, Barbosa-Filho JM. Survey of medicinal plants used in the region Northeast of Brazil. J Rev Bras Farmacogn 2008;18:472-508.
Prasanna V Habbu, Hanumanthachar Joshi, PatilBS. Ph.cog Rev. Review article potential wound healers from plant origin. J Pharmacogn Rev 2007;1(2):14-28.
Brahmachari G, Roy R, Mandal LC, Ghosh PP, Gorai D. A new long-chain alkanediol from the flowers of Argemone mexicana. J Chem Res 2010;11:656-7.
Sharma RA, Ankita Yadav, Richa Bharadwaj. DPPH free radical scavenging activity of phenolic compounds in Argemone mexicana. Int J Pharm Pharm Sci 2013;5(3):683-6.
Raut Smita, Raut Sangeeta, Sen Sudip Kumar, Satpathy Soumya and Pattnaik Deepak. An ethnobotanical survey of medicinal plants in Semiliguda of Koraput district, Odissa, India. J Botany Res Int 2012;5(4):97-107.
Ganesan G. Traditional oral care medicinal plants survey of Tamil Nadu. J Nat Prod Resour 2008;7:166-72.
Chaudhari Rai HN, Pal DC and Tarafdar CR. Less known uses of some plants from the tribal areas of Orissa. J Bull botanical survey of India 1985;17:132-6.
Ahmad I, Beg AZ. Antimicrobial and phytochemical studies on 45 Indian medicinal plants against multi-drug resistant human pathogens. J Ethnopharmacol 2001;74:113-23.
Prabhat K Das, Sujit Pillai, Durga Kar, Debashish Pradhan, Sabuj Sahoo. Pharmacological efficacy of Argemone mexicana plant extract, against cysteamine-induced duodenal ulceration in rats. Indian J Med Sci 2011;65(3):92-9.
Banerji A, Chadha MS and Malshet VG. Isolation of 5-hydroxy-3,6,7,3’,4’-pentamethoxyflavone from Vitex negundo. J Phytochemistry 1969;8:511-2.
Krishna Kumari C, Shanmuga Reddy C, Raja Ratna Reddy Y, Narappa Reddy D and Damodar Reddy C. In vitro antimicrobial activity of the leaf extracts of Argemone mexicana against selected pathogenic microorganisms. Int J Pharm Bio Sci 2013;4(1):536-41.
Simonsen HT, Nordskjold JB, Smitt UM, Nyman U, Palpu P, Joshi P, Varughese G.:In vitroscreening of Indian medicinal plants for antiplasmodial activity. J of Ethnopharmacol 2001;27:195-204.
Das M, Khanna SK. Clinicoepidemiological, toxicological, and safety evaluation studies on argemone oil. J Crit Rev Toxicol 1997;27:273-97.
Papova ME, Boera AN, Dolejs L, Preiniger V, Simamek V, Santanvy F. Isolation and chemistry of alkaloids from plants of the Papaveraceae. J Pant Med 1980;40:156.
Sarita Singh. Quaternary alkaloids of Argemone mexicana. J Pharmaceutical Biology 2010;48(2):158-60.
Pahwa R, Chatterjee VC. The toxicity of Mexican poppy Argemone mexicana L. seeds to rats. J Vet Hum Toxicol 1989;31(6):555-58.
Babu CK, Khanna SK, Das M. Safety evaluation studies on Argemone oil through dietary exposure for 90 days in rats. J Food and Chemical Toxicology 2006;44:1151-57.
Ansari KM, Dhawan A, Khanna SK, Das M. In vivo DNA damaging potential of Sanguinarine alkaloid, isolated from Argemone oil, using alkaline Comet assay in mice. J Food Chem Toxicol 2005;43:147-53.
Stiborova M, Simanek V, Frei E, Hobza P, Ulrichova J. DNA adduct formation from quaternary benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine as revealed by the 32P-postlabeling technique. J Chem Biol Interact 2002;140:231-42.
Valsaraj R, Pushapangadan P, Smit UW, Adersen A, Nyman U. Antimicrobial screening of selected medicinal plants from India. J Etnopharmacol 1997;58:75-83.
Das PK, Misra MK. Some medicinal plants used by the tribal’s of Deomali and adjacent areas of Koraput district, Orissa. Indian J For 1987;10:301-03.
Chopra RN, Nayar SL, Chopra IC. Glossary of Indian Medicinal plants, Council of Industrial Research, New Delhi, 1986.
Jyothi AC, Santosh JP and Ganes PB:Screening of aqueous plant extracts against Beauveria bassiana infection to 5th instar larvae of Bombyx mori L. J of Medicinal plants Res 2011;5:3936-39.
Agra MF, Baracho GS, Nurit K, Basilio IJLD, Coelho VPM. Medicinal and poisonous diversity of the flora of Cariri Paraibanoâ€, Brazil. J Ethnopharmacol 2007;111:383-95.
Singh SK, Pandey VD, Singh A, Singh C. Antibacterial activity of seed extracts of Argemone mexicana L. on some pathogenic bacterial strains. Afr J Biotechnol 2009;8(24):7077-81.
Jeeva GM, Jeeva S, Kingston C. Traditional treatment of skin diseases in South Travancore, Southern Peninsular India. Indian J Tradit Knowl 2007;6:498-501.
Eldridge. J Econ Bot 1995;29:307-32.
Kala CP. J Ethnobiol Ethnomed 2005;1:11.
Girach RD, Aminuddin, Siddioui PA, Khan SA. Int J Pharmacog 1994;32(3):274-83.
Singh VK, Ali ZA, Zaidi STH. J Fitoterapia 1996;67(2):129-39.
Prasad R, Verma SK, Dua R, Kant S, Kushwaha RAS, Agarwal SP. J Lung India 2009;26(3):70-3.
Panghal M, Arya V, Yadav S, Kumar S. J Ethnobiol Ethnomed 2010;6:4.
Kisangau DP, Lyaruu HVM, Ken MH, Joseph CC. J Ethnobiol Ethnomed 2007;3:29.
The Homeopathic Pharmacopoeia of the United States, Vol. I, American Institute of Homeopathy, Boston;1979.p.95-96.
Allen TF. The Encyclopedia of Pure Materia Medica, Vol. 10, M/s. B. Jain Publishers (P) Ltd., New Delhi;1986. p. 324.
Rodriguez-Menchaca A, Ferrer-Villada T, Lara J, Fernandez D, Navarro-Polanco R A, Sanchez-Chapula JA. Block of hERG channels by berberine:mechanisms of voltage and state-dependence probed with site-directed mutant channels. J of Cardiovascular Pharmacology 2006;47:21-9.
Wang YX, Zheng YM. Ionic mechanism responsible for prolongation of cardiac action-potential duration by berberine. J of Cardiovascular Pharmacology 1997;30:214-22.
Wang YX, Zheng YM, Zhou XB. Inhibitory effects of berberine on ATP-sensitiveK+ channel in cardiac myocytes. J European J of Pharmacol 1996;316:307-15.
Yu L, Sun A, Wu Q, Huang X. Effects of protopine on physiological characteristicsof isolated guinea pig atrium. J Zhongguo Yaolixue Tongbao 1999;15:432-34.
Augustus GDPS, Jayabalan M and Seiler GJ. Alternative energy sources from plants of Western Ghats (Tamil Nadu, India). J Biomass and Bioenergy 2003;24(6):437-44.
NovizarN, Ramli N, Mangunwidjaja D, Hambali E, Setyaningsih D, Yuliani S, Yarmo MA and Salimon J. Extraction, transesterification and process control in biodiesel production from Jatropha curcas. European J of Lipid Sci and Technology 2009;111(12):1185-1200.
Bhalke RD, Mandole YP, Mali NB. Phytochemical investigation and effect of various extracts of Argemone mexicana (Papaveraceae) leaves on clonidine and haloperidol-induced catalepsy in mice. J Pharm Res 2009;2(4):765-7.
Singh D and Singh SP. Low cost production of ester from non-edible oil of Argemone mexicana. J Biomass and Bioenergy 2010;34(4):545-49.
Singh S, Singh TD, Singh VP and Pandey VB. Quaternary alkaloids of Argemone mexicana. J Pharm Biology 2010;48(2):158-60.
Ashish Sithta, Ashwani Kumar and Mahla SK. Utilization of Argemone Oil Biodiesel in Commercial Di-Ci Engine. Int J Emerging Technol 2012;3(2):19-23.
Israilov IA, Yuhusov MS. Alkaloids of four Argemone species. J Khim Prir Soedin1986;2:204-06.
Chang YC, Hsieh PW, Chang FR, Wu RR, Liaw CC, Lee KH, Wu YC. Two new protopines argemexicaines A and B and the anti-HIV alkaloid 6-acetonyl dihydrochelerythrine from formasan Argemonemexicana. J Planta Med 2003b;69:148-52.
Haisova K, Slavik J. On the minor alkaloids from Argemone mexicana. J Collect Czech Chem Commun 1975;40:1576-78.
Ito C, Furukawa H. Antifertility studies of isoquinoline alkaloids with special emphasis of structure activity relationship. J Fitoterapia 1990;61:67-71.
Fletcher MT, Takken G, Blaney BJ, Alberts V. Isoquinoline alkaloids and keto-fatty acids of Argemone ochroleuca and A. mexicana (Mexican poppy) seed. An assay method and factors affecting their concentration. Aus J Agric Res 1993;44:265-75.
Tripathi PN, Tripathi M, Pandey VB, Singh D. Alkaloids of Argemone mexicana. Oriental J Chem 1999;15:185-86.
Singh S, Singh TD, Singh VP, Pandey VB. Quaternary alkaloids of Argemone mexicana. J Pharm Biol 2010c;48:158-60.
Singh A, Singh S, Singh S, Singh TD, Singh VP, Pandey VB, Singh, UP. Fungal spore germination inhibition by alkaloids dehydrocorydalmine and oxyberberine. J Plant Prot Res 2009a;49:287-9.
Singh S, Singh TD, Singh VP, Pandey VB. A new benzylisoquinoline alkaloid from Argemone mexicana. J Nat Prod Res 2010b;24:63-67.
Chang YC, Chang FR, Khalil AT, Hsieh PW, Wu YC. Cytotoxic benzophenanthridine and benzylisoquinoline alkaloids from Argemone mexicana. J Z Naturforsch 58c. 2003a;521-26.
Singh S, Pandey VB, Singh TD. Alkaloids and flavonoids of Argemone mexicana. J Nat Prod Res 2012;26:16-21.
Sukumar D, Nambi RA, Sulochana N. Studies on the leaves of Agremone mexicana. J Fitoterapia 1984;55:325-53.
Pathak NKR, Biswas M, Seth KK, Dwivedi SPD, Pandey VB. Chemical investigation of Argemone mexicana. J Die Pharmazie 1985;40:202.
Sarraf S, Tyagi S, Ojha AC, Rawat GS. Phytochemical study of some medicinal plants. J Himalayan Chem Pharm Bull 1994;11:22-4.
Sangwan NK, Malik MS. A long chain alcohol from Argemone mexicana. J Phytochemistry1998;49:755-6.
Dinda B, Banerjee J. Aliphatic compounds from Argemone mexicana. J Chem Ind (London) 1987;12:419-20.
Rahman W, Ilyas M. Flower Pigments. Flavonoids from Argemone mexicana. (Papaveraceae). J Org Chem 1962;27:153-55.
Rukmini C. New, unusual long chain fatty acid (argemonic acid) from Argemone mexicana. J Am Oil Res Soc 1975;52:171-73.
Badami RC, Gunstone FD. Vegetable oils. Examination of component acids of Argemonemexicana seed oil by reversed-phase chromatography. J Sci Food Agric 1962;13:255-57.
Krishnamurthi M, Ramanathan JP, Seshadri TR, Shankaran PR. Flavonol glycosides of Argemone mexicana flowers. Indian J Chem 1965;3:270-72.
Anthal S, Roy R, Gupta VK, Rajnikant, Brahmachari G, Jash SK, Mandal LC. Crystal structure of 3-(β-D glucopyranosyloxy)-5, 7–dihydroxy–2-(4–hydroxyl–3-methoxyphenyl)-4H–1–benzopyran–4-one trihydrate. J X-ray Structure Analysis Online 2012;28:15-6.
Singh S, Singh TD, Pandey VB. Constituents of Argemone species. J Indian Chem Soc 2011;88:275-76.
Bhardwaj DK, Bisht MS, Jain RK, Munyal A. Phenolics from the seeds of Argemone mexicana. J Phytochemistry 1982;21:2154-56.
Singh S, Singh A, Jaiswal J, Singh TD, Singh VP, Pandey VB, Tiwari A, Singh UP. Antifungal activity of the mixture of quaternary alkaloids isolated from Argemone Mexicanaagainst some phytopathogenic fungi. J Arch phytopathol Plant Prot 2010a;43:769-74.
Saleh MA, Rahman FHA, Ibrahim NA, Taha NM. Isolation and structure determination of new nematicidal triglyceride from Argemone mexicana. J Chem Ecol 1987;13:1361-70.
Rahman MM, Alam MJ, Sharmin SA, Rahman MM, Rahman A, Alam MF. In vitro antibacterial activity of Argemone mexicana L (Papaveraceae). CMU J Nat Sci 2009;8:77-84.
Singh SK, Pandey VD, Singh A, Singh C. Antibacterial activity of seed extracts of Argemone mexicana on some pathogenic bacterial strains. African J Biotechnol 2009b;8:7077-81.
Jain RA, Agarwal RC, Dubey D, Verma R, Jain R. Evaluation of antibacterial and antioxidant activity of fruits extract of Argemone mexicana. Int J Pharm innov 2012;2:45-51.
Pandey A, Karanwal V. A study of extract optimization and effect of metal ions on antibacterial properties of Argemone mexicana. Asian J Plant Sci Res 2011;1:43-8.
Abubacker MN, Ramanathan R. Antibacterial activities of Argemone mexicana (Papaveraceae) leaf extract on pathogenic bacterial strains. J Drug Invention Today 2012;4:385-87.
Bhardwaj M, Duhan JS, Kumar A, Surekha. Antimicrobial potential of Argemone mexicana:an in vitro study. Asian J Microbiol Biotechnol Environ Sci 2012;14:353-57.
Rosas-Pinon Y, Mejia A, Diaz-Ruiz G, Aguilara MI, Sanchez-Nietoc S, Rivero-Cruza JF. Ethnobotanical survey and antibacterial activity of plants used in the altiplane region of Mexico for the treatment of oral cavity infections. J Ethnopharmacol 2012;141:860-65.
Alagesaboopathi C, Kalaiselvi N. Antimicrobial activities of the root, stems and leaf extracts of Argemone mexicana. Int J Biosci 2012;2:61-8.
Doss A, Mubaracki HM, Vijayasanthi M, Venkataswamy R. In vitro antibacterial activity of certain wild medicinal plants against Bovine mastitis isolated contagious pathogens. Asian J Pharmaceut Clin Res 2012;5:90-3.
Sharma S, Sharma MC, Kohli DV. Pharmacological screening effect of ethanolic and methanolic extract of fruits and medicinal leaves. Dig J Nanomat Biostr 2010;5:229-32.
Paez-Sanchez E, Fernandez-Saavedra G, Magos GA. Vasoconstrictor and vasorelaxant effects of a methanolic extract from Argemone mexicana (Papaveraceae) in rat aortic rings. J Proc West Pharmacol Soc 2006;49:63-5.
Gupta RS, Dixit VP, Dobhal MP. Antifertility studies of isoquioline alkaloids with special emphasis on structure activity relationship. J Fitoterapia 1990;61(1):67-71.
Das S, Sukul NC. Nematicidal effect of the oil from the seeds of Argemone mexicana. J Env Ecol 1998;6:194-7.
Nath R, Khan MN, Kamalwanshi RS, Diwedi RP. Effect of Argemone mexicana on Meloidogyne juvanica in Okra (Abelmaschus esculentus). Indian J Nematol 1982;12:205-08.
Mojumdar V, Mishara SD. Nematicidal efficacy of some plant products and management of Meloidogyne incognita in pulse crops by soaking seeds in their aqueous extracts. J Curr Nematol 1991;2:27-32.
Rao SM, Chitra KC, Gunesekhar D, Kameswara Rao P. Antifeedant properties of certain plant extracts against second stage larva of Henosephilachna vigintiocta puncata Fabricius. Indian J Entomol 1990;52:681-85.
Kumar S, Singh SK, Baslas RK, Ghildiyal JC, Saxena AK. Lousicidal properties of few aqueous plant extracts. Indian Vet J 2002;79:1136-40.
Singh S, Singh DK. Effect of mollucicidal components of Abrus precatorius, Argemone mexicanaand Nerium indicum on certain biochemical parameters of Lymnaea acuminate. J Phytother Res 1999;13:210-3.
Capasso A, Piacente S, Pizza C, Tommasi ND, Jativa C, Sorrentino L. Isoquinoline alkaloids from Argemone mexicana reduces morphine withdrawal in guinea pig isolated ileum. J Planta Med 1997;63:326-8.
Piacente S, Capasso A, De Tommasi N, Jativa C, Pizza C, Sorrentino L. Different effects of some isoquinoline alkaloids from Argemone mexicana on electrically induced contractions of isolated guineapig ileum. J Phytother Res 1998;11:155-57.
Shah NH, Khan IM, Azam MF. Seed mycoflora of Cowpea and its control with extract of Argemonemexicana. J Bioved 1992;3:167-8.
Asthana A, Mall HV, Dixit K, Gupta S. Fungitoxic properties of latex of plants with special reference to that of Corton bonplandianum Boill. Int J Crude Drug Res 1989;27:25-8.
Srivastava A, Srivastava M. Fungitoxic effect of some medicinal plants (on some food pathogens). Phillippine J Sci 1998;127:181-7.
Upadhyay S, Rai MK. In vitrosensitivity of Curvularia tuberculata Jain:A causal organism die-back diseaseof citrus to different plant extracts. J Indian Medicine1990;1:13-5.
Jaliwala YA, Panda PK, Chourasia N, Bhatt NK, Pandit A, Mohanty PK. In vitro anthelmintic activity of aerial parts of Argemone mexicana. J Pharm Res 2011;4:3173-74.
Majeed A, Taju G, Nathiga Nambi KS, Menaka H. Anthelmintic activity of Argemone mexicanaleaves extract against Pheretima prosthuma and Ascardiagalli. Res J Pharm Biol Chem Sci 2011;2:773-77.
Sakthivadivel M, Eapen A, Dash AP. Evaluation of toxicity of plant extracts against vector of lymphatic filariasis, Culex quinquefasciatus. Indian J Med Res 2012;135:397-400.
Gacche RN, Shaikh RU, Pund MM. In vitro evaluation of anticancer and antimicrobial activity of selected medicinal plants from Ayurveda. Asian J Trad Med 2011;6:127-33.
Gali K, Ramakrishnan G, Kothai R, Jaykar B. In vitro anti-cancer activity of methanolic extract of leavesof Argemone mexicana. Int J Pharm Tech Res 2011;3:1329-33.
Nayak P, Kar DM, Maharana L. Antidiabetic activity of aerial parts of Argemone mexicanain alloxan induced hyperglycaemic rats. J Pharmacologyonline 2011;1:889-903.
Rout SP, Kar DM, Mandal PK. Hypoglycemic activity of aerial parts of Argemone mexicanain experimental rat models. Int J Pharm Pharmaceut Sci 2011;3:533-40.
Schrader FC, Barho M, Steiner I, Ortmann R, Schlitzer M. The antimalarial pipeline –An update. Int J Med Microbiol 2012;302:165-71.
Amartha S, Chaudhari S. Neuropharmacological study of Argemone mexicana. J App Pharm Sci 2011;1:121-26.
Elango G, Abdul Rahuman A, Kamaraj C, Bagavan A, Abduz Zahir A, Santhoshkumar T, Marimuthu S, Velayutham K, Jayaseelan C, Vishnu Kirthi A, Rajakumar G. Efficacy of medicinal plant extracts against Formosan subterranean termite, Coptotermes formosanus. J Ind Crop Prod 2012;36:524-30.