ASSESSMENT OF DRUG RELATED PROBLEMS IN PATIENTS WITH     CHRONIC DISEASES IN THE GENERAL MEDICINE UNITS OF A TERTIARY CARE HOSPITAL

Mannu Meria Wincent; D. Potrilingam; Anagha V.; Sajith Chacko Jacob; Andhuvan G.

doi:10.22159/ijpps.2017v9i12.21660

Authors

Mannu Meria Wincent Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamilnadu, India
D. Potrilingam Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamilnadu, India
Anagha V. Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamilnadu, India
Sajith Chacko Jacob Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamilnadu, India
Andhuvan G. Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamilnadu, India

DOI:

https://doi.org/10.22159/ijpps.2017v9i12.21660

Keywords:

Drug-related problems, Chronic diseases, PCNE, Association

Abstract

Objective: Patients with chronic diseases are more prone to developÂ drug-related problems (DRPs), which can further worsen their quality of life. The aim of this study was to determineÂ factors and medications associated with DRPs in patients with chronic disease.

Methods: This prospective interventional study was conducted for a duration of 6 mo in the in-patients ofÂ general medicine department of PSG Hospital, Coimbatore. DRPs were identified, assessed and recorded as per pharmaceutical care network Europe (PCNE) V5.01 criteria. Chi-square and correlation test were used to analyze the data for identifying factors associated with DRPs.

Results: A total of 137 patients were enrolled for the study,Â of which 66 patients developed DRPs.Â The most prevalent DRP was found to be drug choice problem. The major causes of DRPs were found to be drug and dose selection. Antidiabetic drugs were found to beÂ more associated with drug-related problems. The incidence of drug-relatedÂ problems was high in patients aged between 50 to 59 y. Association between gender,Â length of hospital stays and polypharmacy with DRPs was found to be statistically significant. 58.33%Â of the total drug-related problems were completely solved and 19.05% were partially solved.

Conclusion: The incidence of DRPs in the General Medicine department of the hospital was high.Â The use of an appropriate tool such as PCNE may assist pharmacists and other healthcare professionals to systematically identify,Â categorize and report drug-related problems.

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