TO ASSESS THE DRUG UTILIZATION PATTERN AND TO ANALYZE PHARMACOECONOMICS FOR GERIATRICS IN-PATIENT IN MEDICINE DEPARTMENT OF TERTIARY CARE TEACHING HOSPITAL
DOI:
https://doi.org/10.22159/ijpps.2017v9i12.22334Keywords:
Drug Utilization, Geriatrics, Morbidity, Polypharmacy, PharmacoeconomicsAbstract
Objective: This study was conducted to generate the data on drug utilization pattern among geriatric inpatients in general medicine department.
Methods: The patient's prescriptions and medical record files were randomly selected on the basis of inclusion and exclusion criteria at medicine department of Shri Mahant Indiresh Hospital, Dehradun and the required data for the study were collected in well-designed data collection form and evaluated after the period of 3 months.
Results: Among 175 patients, males were predominant and 31.42% patients were in age group of 71-75 years. Cardiovascular diseases (28%) were most common cause of hospitalization followed by, respiratory disorders (20.57%). Hypertension (25.72%) was most commonly diagnosed disease followed by, diabetes mellitus (22.2%) and chronic obstructive pulmonary disease (14.28%). The most common co-morbidity was hypertension & diabetes mellitus. More than 3 co-morbidities were found in 79 patients. Cardiovascular drugs (22.17%) was most frequently prescribed drug followed by, gastrointestinal drugs (15.30%). Among individual drugs pantoprazole (A02BC02) was most commonly prescribed drugs. Total of 1581 drugs were prescribed with an average of 9.03 drugs per prescription. Only 9.63% drugs were prescribed by generic name. Antimicrobials were prescribed in 146 prescriptions, among them ceftriaxone (J01DD04) was frequently prescribed.
Conclusion: Most of the drugs were utilized by male patients and the rate of polypharmacy was high.
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References
World Health Organization WHO Introduction to Drug Utilization Research Geneva: World Health Organization; 2003.
Shah BR, Gajjar MB, Desai VS. Drug utilization pattern among geriatric patients assessed with the anatomical therapeutic chemical classification/defined daily dose system in a rural tertiary care teaching hospital. Int J Nutr Pharmacol Neurol Dis 2012;2:258-65.
Meena VM, Meena A, Agrawal A. Evaluation of drug utilization pattern in indoor patients of the medicine department at tertiary care teaching hospital in southern Rajasthan. Int J Pharm Sci Res 2015;2:112-7.
Elderly in India-Profile and Programmes. New Delhi: Ministry of Statistics and Programme Implementation. The government of India; 2016.
Harrison's Principles of Internal Medicine. 15th ed. The Biology of Aging; 2015;57:1-7.
Jhaveri BN, Patel TK, Barvaliya MJ, Tripathi CB. Drug utilization pattern and pharmacoeconomics analysis in geriatric medical in‑patients of a tertiary care hospital of India. J Pharmacol Pharmacother 2014;5:15-20.
Annual report to the people on Health. Ministry of Health and Family Welfare, Government of India; 2011.
Purty AJ, Bazroy J, Kar M, Vasudevan K, Veliath A, Panda P. Morbidity pattern among the elderly population in the rural area of Tamil Nadu, India. Turk J Med Sci 2006;36:45-50.
Hohl CM, Dankoff J, Colacone A, Afilavo M. Polypharmacy, adverse drug-related events and potential adverse drug interaction in elderly patients presenting to an emergency department. Ann Emerg Med 2001;38:666-71.
Reamer LB, Emily BM, Temple WS, Jane CA, Kit NS. Polypharmacy: misleading, but manageable. Clin Interv Aging 2008;3:383–9.
Ramanath KV, Suman C. Study on pharmaceutical care in geriatrics of a rural tertiary care hospital. Res J Pharm Biol Chem Sci 2016;7:1568-78.
Supriya P, Abinash P, Snigdha RP. Analysis of drug utilization pattern in elderly in an outpatient department using WHO indicators: a cross-sectional study. Res J Pharm Biol Chem Sci 2016;7:2628-33.
Swathi B, Bhavika. The pattern of medication use among elderly patients attending medicine department in a tertiary care hospital in India. Asian J Pharm Clin Res 2016;9:266-9.
Swapna RN, Rajeshwari B, Venkatadri TV. Drug utilization pattern in geriatric inpatients of medicine department in a tertiary care teaching Hospital. Int J Basic Clin Pharmacol 2015;4:568-73.
Sharma N, Uma A, Shobha K, Rahul P, Alka B, Sinha RR. Screening of prescriptions in the geriatric population in a tertiary care teaching hospital in north India. J Phytopharmacol 2013;2:38-45.
Nimmy, John N, Akshay KN. A study on polypharmacy in senior Indian population. Int J Pharm Chem Biol Sci 2013;3:168-71.
Sultan HA, Khalid YS, Abdul VM. Prescribing pattern of drugs in the geriatric patients in jazan province, KSA. Pharm Pharmacol Int J 2015;2:10-13.
Abraham F, Gladis V, Joseph CM, Phebina MJ, Gloria KS. Drug utilization pattern among geriatric patients in a tertiary care teaching hospital. Asian J Pharm Clin Res 2015;8:191-4.
Mittal N, Mittal R, Singh I, Nusrat S, Malhotra S. Drug utilisation study in a tertiary care center: Recommendations for improving hospital drug dispensing policies. Indian J Pharm Sci 2014;76:308-14.
Geetha S, Sathisha A, Balaji V, Swetha ES. Analysis of drug utilization pattern among hypertensive patients admitted to medical intensive care unit of a tertiary care hospital. World J Pharm Res 2015;4:1320-30.
Lourdu JA, Venkata NK, Udhayalakshmi T, Jayapriya B, Maruti. Drug utilization patterns of geriatric patients admitted in the medicine mepartment of a tertiary care hospital. Int J Pharm Life Sci 2013;4:3087-92.
Sujata S, Nawin P, Singh C, Sagar GC. Drug prescribing pattern and prescription error in elderly: a retrospective study of inpatient record. Asian J Pharm Clin Res 2011;4:129-32.
Veena DR, Padma L, Sapna P. Drug prescribing pattern in elderly patients in a teaching Hospital. IOSR J Dental Med Sci 2012;1:39-42.
Babar HS, Hussain S, Maqsood Z, Dad HA, Khan M, Rahman AA, et al. Adherence to prescription format and compliance with who core prescribing. Indicators J Pharm Sci Res 2014;6:195-9.