SERUM LIPID LEVELS IN PERIODONTITIS PATIENTS: A CASE-CONTROL STUDY
DOI:
https://doi.org/10.22159/ijpps.2018v10i2.23701Keywords:
Periodontitis, Serum lipid levels, Cardiovascular disease, Total cholesterol, High-density lipoprotein, Low-density lipoprotein, Very low-density lipoprotein, TriglyceridesAbstract
Objective: We aimed to evaluate serum lipid levels in periodontitis patients and compared with healthy subjects.
Methods: A case-control study was conducted among 30 participants in the age group of 35-60 y, including 15 subjects in case group with community periodontal index (CPI) score of ≥2 and 15 subjects in the control group with a CPI score of ≤ 1 based on their periodontal status. Fasting blood samples were taken for measurement of lipid profiles, including total cholesterol, triglyceride (TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL) using an enzymatic method. Odds ratio and independent t-test at *p=0.05 significance level were calculated.
Results: Periodontitis patients were 4.1 times at risk to have high triglyceride, 1.3 times at risk to have high total cholesterol and 0.3times at risk to have higher HDL. Independent t-test showed higher total cholesterol/HDL ratio (*p=0.033) and lowered HDL levels (*p=0.027) in periodontitis patients.
Conclusion: Periodontitis group has significantly higher total cholesterol/high-density lipoprotein ratio and lower high-density lipoprotein levels when compared to the healthy group.
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