1,2,4-TRIAZOLES: SYNTHETIC STRATEGIES AND PHARMACOLOGICAL PROFILES
Keywords:
1, 2, 4-triazole, Analgesic, Anticancer, Anticonvulsant, Anti-inflammatory, Antimicrobial, Antioxidant, Microwave, Solid-phaseAbstract
Multicomponent, solid-phase, microwave and grinding methods are the constructive modes in the sustainable synthesis of 1, 2, 4-triazoles and such reactions have attracted enormous interest in recent years. The alternative reaction conditions getting popularity in the recent ecofriendly-economical time have been thoroughly investigated. Literature studies on 1, 2, 4-triazoles have shown that these derivatives possess broad spectrum of biological activities. This review focuses on synthetic strategies and pharmacological properties of 1, 2, 4-triazoles.
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