EVALUATION OF THE EXHAUSTIVE EXTRACTION YIELDS FOR TEUCRIUM POLIUM L. FROM DIFFERENT REGIONS OF THE WEST BANK - PALESTINE

Authors

  • Nidal Amin Jaradat An-Najah National University Faculty of Medicine and Health Sciences Department of Pharmacy

Keywords:

Teucrium polium L, Exhaustive extraction, Organic extraction yield, Aqueous extraction yield

Abstract

Objective: Teucrium polium L. aerial parts have been used by local populations of Palestine for the treatment of various diseases as diabetes mellitus, amoeba, intestinal spasms and diarrhea for that the interest of using this herbal remedy among researchers and populations increased, this study was aimed to evaluate the best area in Palestine that may be considered the best source of collection and cultivation for Teucrium polium plant in the future, to be a good source for manufacturing active pharmaceutical dosage forms from this plant.

Method: The yield of the organic and water extraction method assessed by using exhaustive extraction method, by steeping the plant in ethanol, water and hexane to extract all the chemical ingredients without heating to prevent destroying or changing the plant chemical constituents.

Results: the best aqueous and organic yields were in Bethlehem region (6.4%, 2.6 %), while the lowest aqueous and organic yields were in Qalqilya (4.96%, 1.16%).

Conclusion: We recommended the pharmaceutical companies; Bethlehem region as the best area for cultivation and collection Teucrium plant for manufacturing the best standardized pharmaceutical dosage forms also we recommended the researchers to use the Teucrium plant from this region for their scientific research.

 

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Author Biography

Nidal Amin Jaradat, An-Najah National University Faculty of Medicine and Health Sciences Department of Pharmacy

Head of the Pharmaceutical Chemistry and Technology Division

An-Najah National University Faculty of Medicine and Health Sciences Department of Pharmacy

References

Blumenthal M, Busse WR, Goldberg A. "The complete German Commission E monographs: therapeutic guide to herbal medicines. " American Botanical Council: Austin, TX; 1998. p. 683.

Wangchuk P, Keller PA, Pyne SG, Taweechotipatr M. Inhibition of TNF-alpha production in LPS-activated THP-1 monocytic cells by the crude extracts of seven Bhutanese medicinal plants. J Ethnopharmacol 2013;148(3):1013-7.

Imaga NA. Phytomedicines and nutraceuticals: alternative therapeutics for sickle cell anemia. Sci World J 2013;2013:12.

Wang L, Curtis L. Recent advances in extraction of nutraceuticals from plants. Trends Food Sci Technol 2006;17:300–12.

Poole CF. Thin-layer chromatography: challenges and opportunities. J Chromatogr A 2003;1000:963-84.

Handa S, Khanuja S, Longo G, Rakesh D. Extraction technologies for medicinal and aromatic plants. Trieste: Int Centre Sci High Technol 2008;2:1-10.

Sasidharan S, Chen Y, Saravanan D, Sundram KM, Yoga Latha L. Extraction, isolation and characterization of bioactive compounds from plants' extracts. Afr J Tradit Complementary Altern Med 2011;8:1-10.

Galati EM, Mondello MR, D'Aquino A, Miceli N, Sanogo R, Tzakou O, et al. Effects of Teucrium divaricatum Heldr. ssp. divaricatum decoction on experimental ulcer in rats. J Ethnopharmacol 2000;72:337-42.

Said O, Khalil K, Fulder S, Azaizeh H. Ethnopharmacological survey of medicinal herbs in Israel, the Golan Heights and the West Bank region. J Ethnopharmacol 2002;83:251-65.

The Plant List.org.version 1.1. Published on the Internet; [cited 2014,30 Sept. ]; Available from: http:// www.theplantlist.org/ tpl1.1/record/kew-2679695.

Grieve M. A modern herbal: the medicinal, culinary, cosmetic and economic properties, cultivation and folk-lore of herbs, grasses, fungi, shrubs, & trees with all their modern scientific uses: Courier Dover Publications; 1971:3:71-5.

Abdollahi M, Karimpour H, Monsef-Esfehani HR. Antinociceptive effects of Teucrium polium L total extract and essential oil in mouse writhing test. Pharmacol Res Official J Italian Pharmacol Soc 2003;48:31-5.

Ali N, Ali Shah SW. Antispasmodic activity of Teucrium stocksianum Boiss. Pakistan J Pharm Sci 2011;24:171-4.

Esmaeili MA, Yazdanparast R. Hypoglycaemic effect of Teucrium polium: studies with rat pancreatic islets. J Ethnopharmacol 2004;95:27-30.

Rasekh HR, Khoshnood-Mansourkhani MJ, Kamalinejad M. Hypolipidemic effects of teucrium polium in rats. Fitoterapia 2001;72:937-9.

Zal F, Vasei M, Rasti M, Vessal M. Hepatotoxicity associated with hypoglycemic effects of Teucrium polium in diabetic rats. Arch Iranian Med 2001;4:188-92.

Gharaibeh M, Elayan H, Salhab A. Anorexic effect of Teucrium polium in rats. J Crude Drug Res 1989;1:201–7.

Suleiman MS, Abdul-Ghani AS, Al-Khalil S, Amin R. Effect of Teucrium polium boiled leaf extract on intestinal motility and blood pressure. J Ethnopharmacol 1988;22:111-6.

Tariq M, Ageel AM, al-Yahya MA, Mossa JS, al-Said MS. Anti-inflammatory activity of Teucrium polium. Int J Tissue React 1989;11:185-8.

Couladis M, Tzakou O, Verykokidou E, Harvala C. Screening of some Greek aromatic plants for antioxidant activity. Phytother Res PTR 2003;17:194-5.

Ulubelen A, Topu G, Sönmez U. Chemical and biological evaluation of genus teucrium. In: Atta ur R, editor. Studies in Natural Products Chemistry: Elsevier; 2000. p. 591-648.

Serrilli AM, Ramunno A, Rullo R, Ballero M, Serafini M, Bianco A. The occurrence of phenyl propanoid glycosides in endemic Teucrium species. Nat Prod Res 2007;21:814-8.

Ruhdorfer J, Rimpler H. Teucardosid, ein neues iridoid aus teucrium arduini L. und teucrium hircanicum L. Tetrahedron Lett 1981;22:839-42.

Rizk AM, Hammouda FM, Rimpler H, Kamel A. Iridoids and flavonoids of Teucrium polium herb. Planta Med 1986;2:87-8.

Raei F, Ashoori N, Eftekhar F, Yousefzadi M. Chemical composition and antibacterial activity of Teucrium polium essential oil against urinary isolates of Klebsiella pneumoniae. J Essent Oil Res 2013;26:65-9.

Djabou N, Muselli A, Allali H, Dib Mel A, Tabti B, Varesi L, et al. Chemical and genetic diversity of two Mediterranean subspecies of Teucrium polium L. Phytochem 2012;83:51-62.

Lamnauer D, Batanouny K. A Guide to Medicinal Plants in North Africa. Spain: IUCN; 2005.

Centre for Mediterranean Cooperation IUfCoNaNR, Union internationale pour la conservation de la nature et de ses ressources. A guide to medicinal plants in North Africa: IUCN; 2005.

Guetat A, Al-Ghamdi F. Analysis of the essential oil of the germander Teucrium polium L. aerial parts from the northern regions of Saudi Arabia. Int J Appl Biol Pharm Technol 2014;5:128-35.

Aruna C, Chaithra D, Alekhya C, Yasodamma N. Pharmacognostic studies of aeschynomene indica L. Int J Pharm Pharm Sci 2012;4:7-13

Rojas JJ, Ochoa VJ, Ocampo SA, Muñoz JF. Screening for antimicrobial activity of ten medicinal plants used in Colombian folkloric medicine: A possible alternative in the treatment of non-nosocomial infections. BMC Complementary Altern Med 2006;6(1):2.

Published

01-01-2015

How to Cite

Jaradat, N. A. “EVALUATION OF THE EXHAUSTIVE EXTRACTION YIELDS FOR TEUCRIUM POLIUM L. FROM DIFFERENT REGIONS OF THE WEST BANK - PALESTINE”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 7, no. 1, Jan. 2015, pp. 511-3, https://journals.innovareacademics.in/index.php/ijpps/article/view/3112.

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Short Communication(s)