ANTIBACTERIAL ACTIVITY OF AEGLE MARMELOS (L) CORREA
Keywords:
Aegle marmelos, Antibacterial property, Disc diffusion, Traditional medicineAbstract
Objective: To investigate the antibacterial property of Aegle marmelos (L.) Correa leaf extracts.
Methods: The antibacterial property of A. marmelos crude methanolic and chloroform leaf extracts was evaluated through agar disc diffusion method. Two Gram-positive (Bacillus subtilis, Staphylococcus aureus) and three Gram-negative bacteria (Pseudomonas aeruginosa, Klebsiella pneumonia, Escherichia coli) were used for the study.
Results: The zone of inhibitions obtained from the agar diffusion disc method showed that methanolic and chloroform leaf extracts exhibited maximum (15 mm) activity against P. aeruginosa and 18 mm against S. aureus, respectively. Both extracts were partially active against B. subtilis and K. pneumonia. The activity was maximum at higher concentration (100mg/ml) and decreased gradually with the decrease in the concentration of the extracts against all the test pathogens.
Conclusions: From this study, it can be concluded that A. marmelos extracts may be a potential antibacterial agent against both Gram-positive and Gram-negative bacteria. The antibacterial property may be attributed to different phytoconstituents present in the crude methanolic and chloroform extracts.
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