A CRITICAL LITERATURE REVIEW AND AUDIT OF REAL WORLD DATA TO INFORM THE RELATIONSHIP BETWEEN MENTAL ILL-HEALTH AND TYPE-2 DIABETES FAVOURABLE PROGNOSIS

NASREEM BIBI; BAHTA WARA; SAQIB MUGHAL; HANA MORRISSEY; PATRICK BALL

doi:10.22159/ijpps.2020v12i2.36393

Authors

NASREEM BIBI School of Pharmacy, University of Wolverhampton, Wulfruna Street, Wolverhampton, WV1 1LY, United Kingdom
BAHTA WARA School of Pharmacy, University of Wolverhampton, Wulfruna Street, Wolverhampton, WV1 1LY, United Kingdom
SAQIB MUGHAL School of Pharmacy, University of Wolverhampton, Wulfruna Street, Wolverhampton, WV1 1LY, United Kingdom
HANA MORRISSEY School of Pharmacy, University of Wolverhampton, Wulfruna Street, Wolverhampton, WV1 1LY, United Kingdom https://orcid.org/0000-0001-9752-537X
PATRICK BALL School of Pharmacy, University of Wolverhampton, Wulfruna Street, Wolverhampton, WV1 1LY, United Kingdom http://orcid.org/0000-0001-8918-2119

DOI:

https://doi.org/10.22159/ijpps.2020v12i2.36393

Keywords:

Anxiety, Depression, Type 2 diabetes mellitus, Mental ill-health, Real-world data

Abstract

Objective: The aim of this scoping study was to identify gaps in the current literature and understand the T2DM and MIH comorbidity trends in the local population from the West Midlands, UK to inform future studies.

Methods: This project was a scoping study of two parts; a critical review and a clinical audit. A thematic approach was used to group studies based on their overall study outcome. The clinical audit data was used to compare the local patient population to the patterns identified in the literature reviewed.

Results: The reviewed studies reported a relationship between T2DM control and both depression and anxiety, but did not agree on its significance. The clinical audit of 71 patients diagnosed with T2DM showed that 73% of males presented with poor diabetes control (HbA1c>7) compared to females (46%). Conversely, females exhibited a higher prevalence of MIH (45%) compared to males (31%).

Conclusion: From both this audit of the literature and local data, it remains unclear whether mental-ill health is a major driver for medication non-adherence behaviour and uncontrolled diabetes. Further studies are recommended to further understand this comorbidity.

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