EVALUATION OF EFFICACY OF EPIDURAL BUTORPHANOL TARTRATE FOR POSTOPERATIVE ANALGESIA

Authors

  • R. Venkatraman SRM MEDICAL COLLEGE HOSPITAL, POTHERI - 603203, TAMILNADU, INDIA
  • R. Sandhiya ESI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCE & RESEARCH, CHENNAI.

Keywords:

Butorphanol, Epidural anaesthesia, Postoperative analgesia, Sedation, Abdominal, Gynaecological surgeries

Abstract

Objectives: The objective of this study was to evaluate the efficacy of epidural butophanol tartrate in postoperative analgesia and to monitor its side effects.

Methods: 80 patients of ASA 1 and 2 scheduled for elective abdominal and gynaecological procedure were chosen for the study. At the end of surgery, study group received 2mg of butorphanol in 10 ml normal saline through an epidural catheter and the control group received 10 ml of normal saline. Postoperatively vitals, VAPS, sedation score and side effects were pointed. Patients received rescue analgesic when VAPS was greater than 6.

Results: Epidural butorphanol produced duration of analgesia of 7.46 ± 1.35 hours. The quality of analgesia was excellent in 75% of patients and good in 25% of patients. The two main adverse effects observed were sedation and vomiting. Sedation may be beneficial to patients in the immediate postoperative period.

Conclusion: Epidural butorphanol produces long lasting, good quality analgesia with minimal side effects.

 

Downloads

Download data is not yet available.

Author Biographies

R. Venkatraman, SRM MEDICAL COLLEGE HOSPITAL, POTHERI - 603203, TAMILNADU, INDIA

ASSOCIATE PROFESSOR, DEPARTMENT OF ANAESTHESIA

R. Sandhiya, ESI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCE & RESEARCH, CHENNAI.

SENIOR RESIDENT

References

Dhimar AA, Patel MG, Swadia VN, Desai DJ. Epidural butorphanol: comparison of two different doses for lower limb orthopaedic surgery. J Anaesth Clin Pharmacol 2006;22(1):47-52.

Jasleen Kaur, Sukhminder Jit Singh Bajwa. Comparison of epidural butorphanol and fentanyl as adjuvants in the lower abdominal surgery: a randomized clinical study. Saudi J Anesthesia 2014;8(2):167-71.

Singh Bhagwat, Nihlani Sanjay. Postoperative analgesia: a comparative study of epidural Butorphanol and epidural Tramadol. J Adv Res Biol Sci 2011;3(2):86-9.

Bromage PR, Camporesi E, Chestnut D. Epidural narcotics for postoperative analgesia. Anesth Analg 1980;59:473-80.

Reiz S, Westberg M. Side-effects of epidural morphine. Lancet 1980;2(8187):203-4.

Rosow CE. Butorphanol in perspective. Acute Care 1988;(12, Suppl 1):2-7.

Palacios QT, Jones MM, Hawkins JL. Post caesarean section analgesia: a comparison of epidural butorphanol and morphine. Can J Anaesth 1991;38:24-30.

Abboud TK, Moore M, Zhu J. Epidural butorphanol or morphine for the relief of post-cesarean section pain: ventilatory response to carbon dioxide. Anesth Analg 1987;66:887-93.

Bharti N, Chari P. Epidural butorphanol-bupivacaine analgesia for postoperative pain relief after abdominal hysterectomy. J Clin Anesth 2009;21:19-22.

Shrestha CK, Sharma KR, Shrestha RR. Comparative study of epidural administration of 10 ml of 0.1% bupivacaine with 2mg butorphanol and 10 ml of 0.25% plain bupivacaine for analgesia during labor. JNMA J Nepal Med Assoc 2007;46:1-6.

Ruchi Gupta, Simmerpreet Kaur, Saru Singh, KS Aujla. A comparison of epidural butorphanol and tramadol for postoperative analgesia using CSEA technique. J Anaesth Clin Pharmacol 2011;27(1):35-8.

Tan PH, Chou AK, Perng JS, Chung HC, Lee CC, Mok MS. Comparison of epidural butorphanol plus clonidine with butorphanol alone for postoperative pain relief. Acta Anaesthesiol Sin 1997;35:91-6.

Gupta R, Kaur S, Singh S, Aujla KS. A comparison of epidural butorphanol and tramadol for postoperative analgesia using CSEA technique. J Anaesthesiol Clin Pharmacol 2011;27:35-8.

Pokharel K1, Rahman TR, Singh SN, Bhattarai B, Basnet N, Khaniya S. The efficacy and safety of low dose epidural butorphanol on postoperative analgesia following cesarean delivery. JNMA J Nepal Med Association 2008;47(170):57-61.

Hunt CO, Naulty JS, Malinow AM, Datta S, Ostheimer GW. Epidural butorphanol-bupivacaine for analgesia during labor and delivery. Anesth Analg 1989;68:323-7.

Ackerman WE, Juneja MM, Kaczorowski DM, Colclough GW. A comparison of the incidence of pruritus following epidural opioid administration in the parturient. Can J Anesth 1989;36:388-91.

Published

01-02-2015

How to Cite

Venkatraman, R., and R. Sandhiya. “EVALUATION OF EFFICACY OF EPIDURAL BUTORPHANOL TARTRATE FOR POSTOPERATIVE ANALGESIA”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 7, no. 2, Feb. 2015, pp. 52-54, https://journals.innovareacademics.in/index.php/ijpps/article/view/3837.

Issue

Section

Original Article(s)