ANTIBACTERIAL ACTIVITIES OF SCYTONEMA HOFMAN EXTRACTS AGAINST HUMAN PATHOGENIC BACTERIA
Keywords:
Scytonema hofman, MIC valueAbstract
Objective: The present study is focused, to evaluate the effectiveness of organic solvent or aqueous extracts of Scytonema hofman against some human bacterial pathogens.
Methods: The aqueous and organic solvent extracts of Scytonema hofman were analyzed for their antibacterial property against some of the human bacterial pathogens by agar well diffusion technique followed by determination MIC value.
Results: The results of the present study revealed that chloroform extracts of Scytonema hofman showed a maximum inhibition zones against Escherichia coli (17.9 mm) followed by Klebsiella pneumonia (14.3 mm) and Pseudomonas aeruginosa (11.6 mm) but less effective against Staphylococcus aureus (4.8 mm). Similar result was also observed in case of ethanolic extract but having fewer inhibition zones when compared with chloroform extract. The aqueous extract was found to be insignificant along with other five organic solvent against all the tested human bacterial pathogens. The MIC values of chloroform extract were found to be 31.25 µg/ml against Escherichia coli and Pseudomonas aeruginosa, whereas in case of Klebsiella pneumonia the value was found to be 250 µg/ml.
Conclusion: The chloroform extract of Scytonema hofman was found to be the most effective antibacterial property against all the tested bacterial pathogens.
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