OPUNTIA ELATIOR MILL.–ITS PHYTOCHEMISTRY AND PHARMACOLOGICAL PROPERTIES-A REVIEW

Authors

DOI:

https://doi.org/10.22159/ijpps.2022v14i2.43400

Keywords:

Nagaphani, Opuntia elatior, Phytochemistry, Pharmacology, Red prickly pear

Abstract

Opuntia elatior Mill. (OE) (Family Cactaceae), commonly recognized as Red Prickly pear, is a plant of varied nutritional and medicinal benefits. The species has been scrutinized for the composition and wide array of pharmacological activities. This review is attempted with an aim to document the updated status of OE with respect to its phytochemistry and pharmacological actions. The data is collected from the extensive review of literatures from scientific articles, dissertations and books available on various web-based search engines such as Pub-med, Google-scholar and Science direct and few unpublished observations. The fruit is reported to be rich in carbohydrates, flavonoids, phenolics, betalains, vitamin C and minerals like calcium, magnesium, iron, zinc, copper, and potassium. Extract and the fruit as a whole are reported for anti-oxidant, hematinic, anti-leukemic, anti-diabetic, analgesic and anti-inflammatory, anti-fertility, broncho-dilatory, mast cell degranulation, radio-protective and anti-arthritic activities. It is reported to be safe for administration in a dose dependent manner. OE is a nutritionally and medicinally important drug with a wide range of traditional and pharmacological applications. There is a vast scope for research on the varied traditional claims of this drug. This review might help for the further research on the species.

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References

Hazarika TK, Lalramchuana L, Nautiyal BP. Studies on wild edible fruits of Mizoram, India used as ethno-medicine. Genet Resour Crop Evol. 2012;59(8):1767-76. doi: 10.1007/s10722-012-9799-5.

Krishna H, Saroj PL, Maheshwari SK, Singh RS, Meena RK, Chandra R. Underutilized fruits of arid and semi-arid regions for nutritional and livelihood security. International Journal of Minor Fruits. Med Aromat Plants. 2019;5(2):1-14.

Pasiecznik N. Invasive species compendium. France: Agroforestry Enterprises; 2019.

Prajapati S, Acharya RN. Opuntia elatior Mill. (Nagaphani): a review on its ethnobotany, phytochemical and pharmacological properties. Ann Ayurvedic Med. 2015;4:3-4.

Patel KN, Ishnava KB Asao T, Asaduzzaman M, editors. Evaluation of nutritional and medicinal properties of Opuntia elatior mill. Phytochemicals-source of antioxidants and role in disease prevention. IntechOpen; 2018.

Bhatt MR, Sheth DD, Khara J. Nutritional potential and stability of Opuntia elatior Mill. fruit juice [dissertation]. Baroda: Maharaja Sayajirao University; 2012.

Roghelia V, Panchal J. Physicochemical characteristics of cactus pear fruits. J Pharm Chem Biol Sci. 2016;4(1):119-25.

Patel H, Prajapati S, Acharya R, Harisha CR, Shukla V. A preliminary phyto-pharmacognostical evaluation of Opuntia elatior mill. (Nagaphani or Hathlo-thore) fruit. Int J Ayurvedic Med. 2015;6(4):310-6.

Bhatt MR, Nagar PS. Evaluation of physicochemical property and fatty acid composition of Opuntia elatior seed oil. J Prof Assoc Cactus Dev. 2013;15:13-9.

Ganguly AK, Govindachari TR, Mohamed PA. Structure of opuntiol, a constituent of Opuntia elatior. Tetrahedron. 1965;21(1):93-9. doi: 10.1016/S0040-4020(01)82206-7.

Halimfanezi L, Rusdi AR. A review: analysis of betacyanin levels in various natural products. Asian J Pharm Res Dev. 2020;8(5):89-95.

Phytochemical and GC-MS analysis of the ethanol fruit extract of Opuntia elatior. Open Database; 2021. Available from: https://fdocuments.in/document/chapter-ii.pdf. [Last accessed on 22 Sep 2021]

Sutariya B, Saraf M. Betanin, isolated from fruits of opuntia elatior mill attenuates renal fibrosis in diabetic rats through regulating oxidative stress and TGF-β pathway. J Ethnopharmacol. 2017;198:432-43. doi: 10.1016/ j.jep.2016.12.048, PMID 28111218.

Chauhan SP, Navin S, Suhagia B, Mardia RB. Phytochemical screening of fruits of Opuntia elatior mill. AJPTR 2013;3(2):1-16.

Chamundaiah RM, Shivabasavaiah KH. Ethnomedicinal value of Opuntia elatior fruits and its effects in mice. J Pharm Res. 2012;5(8):4554-8.

Kotadiya CR, Patel UD, Chauhan VB, Patel HB, Modi CM, Bhatt PR. In vitro antioxidant and antidiabetic activity of hydroalcoholic extract of Opuntia elatior fruit as well as quercetin. Int J Sci Environ Technol. 2017;6(2):1028-35.

Itankar P, Acharya S, Arora S, Thakre P. OA01.47. Phytochemical study and evaluation of antileukemic activity of ripe fruit of opuntia elatior. Mill Ancient Sci Life. 2012;32(5):47. doi: 10.4103/0257-7941.112018.

Sanyal SK, Acharya RN, Nariya MK, Gamit R. Toxicological study of Opuntia elatior Mill., fruit (ripen) juice: A folklore medicinal plant. Int J Green Pharm. 2015;9(4):39-44.

Shah TM, Patel UD, Nimavat VR, Fefar DT, Kalaria VA, Javia BB, Savsani HH, Kotadiya CR. Toxico-pathological studies on experimentally induced lead acetate toxicity in broiler chickens with protective effect of opuntia elatior and withania somnifera. Asian J Anim Sci. 2016;11(1):33-9. doi: 10.15740/HAS/TAJAS/11.1/33-39.

Alam S. Cytotoxic and Antioxidant activity in aqueous fraction of Opuntia elatior extract [dissertation]. Dhaka: East-West University; 2011.

Islam S. In vitro pharmacological investigations of dichloromethane fraction of Opuntia elatior, Dhaka; 2015. Available from: http://dspace.edubd.edu/handle/2525.1690. [Last accessed on 10 Sep 2021]

Kotadiya C, Patel UD, Modi CM, Patel HB, Kalaria VA, Chauhan VB. Effect of Opuntia elatior fruit juice and quercetin administration on glucose level, lipid profile, hyperalgesic response and spontaneous motor activity in diabetes rats. The Pharm Innov J. 2017;6(8):150-5.

Poonia K, Sharma J. Effect of Opuntia elatior on alteration in blood glucose level induced by gamma radiation in mice. Int Res J Pharm. 2019;10(6):43-7. doi: 10.7897/2230-8407.1006201.

Poonia K, Sharma J. Effect of Opuntia elatior on cholesterol level alterations induced by gamma radiations in swiss albino mice. Asian J Pharm Clin Res. 2019;12(3):578-81.

Poonia K, Sharm J. Effect of Opuntia elatior on alteration in glutamic oxaloacetic transaminase activity induced by gamma radiation in swiss albino mice. Int J Lifescience Pharm Res. 2020;10(4):90-5.

Poonia K, Sharma J. Radioprotective effect of Opuntia elatior on blood of swiss albino mice. IJPSR. 2019;10(5):2306-14.

Chauhan SP, Sheth NR, Suhagia BN. Evaluation of bronchodilatory properties of fruits of Opuntia elatior mill. Egypt Pharmaceut J. 2015;14(1):44-9. doi: 10.4103/1687-4315.154717.

Chauhan SP, Sheth NR, Suhagia BN. Effect of fruits of opuntia elatior mill on mast cell degranulation. J Pharm Bioallied Sci. 2015;7(2):156-9. doi: 10.4103/0975-7406.148779, PMID 25883521.

Chauhan SP, Sheth NR, Suhagia BN. Analgesic and anti-inflammatory action of opuntia elatior mill fruits. J Ayurveda Integr Med. 2015;6(2):75-81. doi: 10.4103/0975-9476.159025, PMID 26166996.

Chamundaiah RM, Shivabasavaiah ST. Fertility suppression by the fruit extract of Opuntia elatior in the male rat: possible extragonadal action. J Endocrinal Reprod. 2014;18(1):7-16.

Chamundaiah RM, Krishna Ram H, Shivabasavaiah. Reproductive toxicity of opuntia fruit extract in male swiss albino mice. Int J Adv Biol Res. 2013;3(3):464-9.

Patel H, Prajapati S, Ranade A, Acharya RN, Nariya MK. Evaluation of the haematinic activity of Opuntia elatior Mill. fruit. Indian J Nat Prod Resour. 2018;9(1):39-46.

Chauhan SP, Sheth NR, Suhagia BN. Haematinic evaluation of fruits of opuntia elatior mill. on mercuric chloride induced anemia in rats. Int J Res Ayurveda Pharm. 2014;5(1):115-22. doi: 10.7897/2277-4343.05124.

Chauhan SP, Sheth NR, Suhagia BN. Hematinic effect of fruits of Opuntia elatior mill. on phenylhydrazine-induced anemia in rats. Ayu. 2015;36(2):208-13. doi: 10.4103/0974-8520.175549, PMID 27011725.

Vadhvana V. Haematinic activity of Nagaphani (Opuntia elatior Mill.) on Haemolytic anemia in Albino rats. Jamnagar: GAU; 2019.

Prajapati S. A pharmacological and pharmaco-therapeutical evaluation of fruit of Nagaphani (Opuntia elatior mill.) on Pandu [thesis]. Jamnagar: Gujarat Ayurved University; 2016.

Prajapati S, Ranade A, Acharya R, Goyal M. Clinical evaluation of Opuntia elatior Mill. (Nagaphani) fruit in the management of Pandu with special reference to Geriatric anemia. Glob J Res Med Plants Indigenous Med. 2016;5(4):114-20.

Prajapati SM, Anand S, Acharya RN, Goyal M. Effect of Opuntia elatior mill. (Nagaphani) in the management of Pandu Roga w.s.r. to iron deficiency anaemia; an open labelled randomized standard controlled clinical trial. Ayu. 2021;4(2):87-97.

Chauhan S, Gopani T, Suhagia B, Gupta S, Patel K, Patel M. Clinical evaluation of Beet root and prickly pear in the management of anemia: an observational study. J Ayurveda Med Sci. 2018;2(4):274-7. doi: 10.5530/jams.2017.2.30.

Roome T, Aziz S, Razzak A, Aslam Z, Lubna JKS, Jamali KS, Sikandar B, Fatima T, Abidi L, Imran M, Faizi S, Shah MR. Opuntioside, opuntiol and its metallic nanoparticles attenuate adjuvant-induced arthritis: novel suppressors of toll-like receptors-2 and-4. Biomed Pharmacother. 2019 April;112:108624. doi: 10.1016/j.biopha.2019.108624, PMID 108624.

Singchai B, Pongputthachat D, Daengkhwanthong U. Antioxidant and antimicrobial activities of Opuntia elatior fruit. Science and genetic engineering. The 55th academic conference of kasetsart university; 2021. p. 240-5. Available from: https://agris.fao.org/agris-search/search.do?recordID=TH2018000395. [Last accessed on 30 Dec 2021].

Published

01-02-2022

How to Cite

R., S., and R. ACHARYA. “OPUNTIA ELATIOR MILL.–ITS PHYTOCHEMISTRY AND PHARMACOLOGICAL PROPERTIES-A REVIEW”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 14, no. 2, Feb. 2022, pp. 6-13, doi:10.22159/ijpps.2022v14i2.43400.

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Section

Review Article(s)