A PROSPECTIVE OBSERVATIONAL STUDY ON PREVALENCE AND TREATMENT OF URINARY TRACT INFECTIONS IN A TERTIARY CARE TEACHING HOSPITAL IN TELANGANA STATE

Authors

  • SYEDA RANA NIKHAT Department of Pharmacology, Mesco College of Pharmacy, Mustaidpura, Hyderabad, Telangana State, 500006, India
  • JUVEYRIA KAREEM Department of Pharmacology, Mesco College of Pharmacy, Mustaidpura, Hyderabad, Telangana State, 500006, India
  • ASMA LATEEF Department of Pharmacology, Mesco College of Pharmacy, Mustaidpura, Hyderabad, Telangana State, 500006, India
  • SYEDA RUHI FATIMA Department of Pharmacology, Mesco College of Pharmacy, Mustaidpura, Hyderabad, Telangana State, 500006, India
  • RAFIA SULTANA Department of Clinical Pharmacology, Osmania General Hospital, Afzal Gunj, Hyderabad, Telangana State, 500012, India

DOI:

https://doi.org/10.22159/ijpps.2022v14i12.46191

Keywords:

Pyelonephritis, Symptomatic asymptomatic bacteuria, Cystitis

Abstract

Objective: To study the Prevalence of urinary tract infections and related risk factors and to study the Management of urinary tract infections.

Methods: This was a prospective observational study conducted in General Medicine Department, Osmania General Hospital (OGH), a tertiary care teaching hospital in Telangana State, where patients presenting or highly suspicious of having UTIs were included in the study. Pregnant women, Children, Patients who are not willing to participate were excluded from the study. Data was collected in predesigned Data collection forms.

Results: Over a period of 6 Mo a total of 75 UTI cases were observed in General Medicine Department of OGH, which included 33 Males, and 42 Females. High prevalence of UTI were observed in Females in the middle age group i.e. 31-45 y, whereas in Males, in senior adult group i.e.,>60 y. The age group 18-30 y have shown the dominance of Uncomplicated UTIs(19%) and Primary UTIs (17%) and the age group>60 y have shown the dominance of Complicated UTIs (25%) and Recurrent UTIs(23%). The most common causative organism was found to be E. coli (69.3%). It was confirmed that the most common risk factor was found to be Diabetes Mellitus, followed by Hypertension and Chronic Kidney Disease. The most common antibiotic prescribed for UTI was Piperacillin+Tazobactum and for fungal UTIs, an antifungal drug i.e., Fluconazole was prescribed.

Conclusion: E. coli are the major cause of UTIs among patients It is discovered that UTI is common among females. Hospitalisation, married individuals, Diabetes mellitus, genitourinary tract abnormalities, congestive cardiac failure, hypertension, prostatitis and female gender are the most important risk factors of UTIs. Appropriate measures may help to reduce UTIs due to these associated factors.

Downloads

Download data is not yet available.

References

Thattil SJ, Santhosh S. Prevalence of UTI in different age groups in a tertiary Care Hospital and their antibiogram. Int J Contemp Med. 2018;5(1):3-6.

Flores Mireles AL, Walker JN, Caparon M, Hultgren SJ. Urinary tract infections: epidemiology, mechanisms of infection and treatment options. Nat Rev Microbiol. 2015;13(5):269-84. doi: 10.1038/nrmicro3432, PMID 25853778.

Vasudevan R. Urinary tract infection: an overview of the infection and the associated risk factors. JMEN. 2014;1(2):42-54. doi: 10.15406/jmen.2014.01.00008.

Ronald A. The etiology of urinary tract infection: traditional and emerging pathogens. Am J Med. 2002;113 Suppl 1A:14S-9S. doi: 10.1016/s0002-9343(02)01055-0, PMID 12113867.

Nicolle LE. Resistant pathogens in urinary tract infections. J Am Geriatr Soc. 2002;50(7) Suppl:S230-5. doi: 10.1046/j.1532-5415.50.7s.3.x, PMID 12121518.

John MS, Meenakshi K, Lakshmi PM, Reddy PS. Prevalence and distribution of bacterial pathogens causing urinary tract infections in humans: A study from Tertiary Care Hospital in AP, India. Int J Curr Microbiol Appl Sci. 2015;4(2):251-7.

Prakash D, Saxena RS. Distribution and antimicrobial susceptibility pattern of bacterial pathogens causing urinary tract infection in urban community of Meerut City, India. ISRN Microbiol. 2013;2013:749629. doi: 10.1155/2013/749629, PMID 24288649.

Faryabi R, Mathew J, Palaye M, Nair S, Shivashankar S, Shetty PK. Antibiotic utilization in patients with complicated urinary tract infection in the medicine wards of a South Indian tertiary care teaching hospital. Res J Pharm Biol Chem Sci. 2014;5(4):87-94.

Aggarwal N, Lotfollahzadeh S. Recurrent urinary tract infections. In: Treasure Island, (FL): Stat Pearls Publishing; 2022. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557479. [Last accessed on 05 Nov 2022]

Christy VR, Athinarayanan G, Mariselvam R, Dhasarathan P, Singh RAJA. Epidemiology of urinary tract infection in South India. Biomed Res Clin Prac. 2019;4:1-5.

Ullah A. Prevalence of symptomatic urinary tract infections and antimicrobial susceptibility patterns of isolated uropathogens in kohat region of Pakistan. MOJBM 2018;3(2). doi: 10.15406/mojbm.2018.03.00082.

Ravi B, KS. Bacteria associated with urinary tract infection in pregnant women with overview of their antibiotic susceptibility tests. Int J Curr Pharm Sci. 2022 Jul 15;14(4):10-5.

Babu AS, Davis D, Joseph N, Joshy N, KK Urinary. Tract infection: prescribing pattern of antibiotics at a tertiary care Hospital. LP. Asian J Pharm Clin Res. 2017 May 1;10(5):255-7.

Chaturvedi A, Gupta B, Chaturvedi A, Sisodiya R, Sharma R. Study of magnitude of UTI caused by Esbl-producing Escherichia coli and associated risk factor S. Asian J Pharm Clin Res. 2022;15(6):19-21. doi: 10.22159/ajpcr.2022.v15i6.43478.

Published

01-12-2022

How to Cite

NIKHAT, S. R., J. KAREEM, A. LATEEF, S. R. FATIMA, and R. SULTANA. “A PROSPECTIVE OBSERVATIONAL STUDY ON PREVALENCE AND TREATMENT OF URINARY TRACT INFECTIONS IN A TERTIARY CARE TEACHING HOSPITAL IN TELANGANA STATE”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 14, no. 12, Dec. 2022, pp. 1-5, doi:10.22159/ijpps.2022v14i12.46191.

Issue

Section

Original Article(s)

Most read articles by the same author(s)