EVALUATION OF INCIDENCE OF MALIGNANCY IN SOLITARY THYROID NODULE AT A TERTIARY CARE HOSPITAL

MOHAMMAD NOOR ALAM; VIJAYLAXMI DULANGE; SADIA AFREEN S. ALAM; PRAMOD

doi:10.22159/ijpps.2023v15i5.47538

Authors

MOHAMMAD NOOR ALAM Department of General Surgery, GIMS, Kalaburgi, Karnataka, India
VIJAYLAXMI DULANGE Department of General Surgery, GIMS, Kalaburgi, Karnataka, India
SADIA AFREEN S. ALAM Medical Oncology Resident, S. L. Raheja Hospital, Mumbai, India
PRAMOD Department of General Surgery, GIMS, Kalaburgi, Karnataka, India

DOI:

https://doi.org/10.22159/ijpps.2023v15i5.47538

Keywords:

Malignancy, Age and Sex, Solitary thyroid nodule

Abstract

Objective: This study aims to identify the incidence of malignancy in solitary nodule thyroid in a tertiary care hospital in Kalaburagi, Karnataka.

Methods: This was a prospective non-randomized hospital-based interventional study carried out on 50 patients over a period of 1 y, who presented with clinically palpable solitary thyroid swellings and subsequently underwent surgery for the same at the Department of General surgery, Gulbarga Institute of Medical Sciences, Kalaburagi, Karnataka.

Results: Over the total duration of the study period, there were 50 cases of clinically detected solitary thyroid nodule with a high female preponderance. The mean age of the incidence of solitary thyroid nodule was 40.6 y. The incidence of malignancy in solitary thyroid nodule was found to be 18%.

Conclusion: It is concluded from the present study that 18% of solitary thyroid nodules are malignant, with female preponderance and a mean age of solitary thyroid nodule is 40.62 y.

Downloads

Download data is not yet available.

References

Palani V, Reshma S. A clinical study of incidence of malignancy in solitary thyroid nodule in a tertiary care hospital. Int Surg J. 2019;6(1):293-5.

Yeung MJ, Serpell JW. Management of the solitary thyroid nodule. Oncologist. 2008 Feb;13(2):105-12. doi: 10.1634/theoncologist.2007-0212, PMID 18305054.

Papini E, Monpeyssen H, Frasoldati A, Hegedüs L. European Thyroid Association clinical practice guideline for the use of image-guided ablation in benign thyroid nodules. Eur Thyroid J. 2020;9(4):172-85. doi: 10.1159/000508484, PMID 32903999.

Tai JD, Yang JL, Wu SC, Wang BW, Chang CJ. Risk factors for malignancy in patients with solitary thyroid nodules and their impact on the management. J Cancer Res Ther. 2012 Jul 1;8(3):379-83. doi: 10.4103/0973-1482.103516, PMID 23174718.

Unnikrishnan AG, Kalra S, Baruah M, Nair G, Nair V, Bantwal G. Endocrine Society of India management guidelines for patients with thyroid nodules: a position statement. Indian J Endocrinol Metab. 2011 Jan;15(1):2-8. doi: 10.4103/2230-8210.77566, PMID 21584159.

Usha Menon V, Sundaram KR, Unnikrishnan AG, Jayakumar RV, Nair V, Kumar H. High prevalence of undetected thyroid disorders in an iodine sufficient adult south Indian population. J Indian Med Assoc. 2009 Feb 1;107(2):72-7. PMID 19585813.

Reena N. Megha G, Jyoti C, Chawda H, Manoj KM. Estimation of the cytomorphological spectrum of thyroid lesions by fine-needle aspiration cytology based on Bethesda system for reporting in tertiary care hospital. Asian J Pharm Clin Res. 2022;15(10):134-6.

Davies L, Welch HG. Increasing incidence of thyroid cancer in the United States, 1973-2002. JAMA. 2006 May 10;295(18):2164-7. doi: 10.1001/jama.295.18.2164, PMID 16684987.

Cole WH, Majarakis JD, Slaughter DP. Incidence of carcinoma of the thyroid in nodular goiter. J Clin Endocrinol Metab. 1949 Oct 1;9(10):1007-11. doi: 10.1210/jcem-9-10-1007, PMID 18142433.

Gupta M, Gupta S, Gupta VB. Correlation of fine needle aspiration cytology with histopathology in the diagnosis of solitary thyroid nodule. J Thyroid Res. 2010 Apr 18;2010:379051. doi: 10.4061/2010/379051, PMID 21048838.

Anitha S, Ravimohan TR. A study of incidence of malignancy in solitary nodule of the thyroid. J Contemp Res. 2016;3(4):993-5.

Aggarwal SK, Jayaram GI, Kakar AR, Goel GD, Prakash RA, Pant CS. Fine needle aspiration cytologic diagnosis of the solitary cold thyroid nodule. Comparison with ultrasonography, radionuclide perfusion study and xeroradiography. Acta Cytol. 1989 Jan 1;33(1):41-7. PMID 2644743.

Fenn AS. Solitary nodule of thyroid gland. Ind J Surg. 1980;42:175-1.

Bhansali SK. Solitary nodule in thyroid gland. Indian J Surg. 1982;55:547.

Rehman AU, Lodhi S, Anwar MI. Histopathological evaluation of 432 cases of goiter. Ann King Edward Med Univ. 2009;15(2):54.

Musthafa SM, DSAM, Daniel R, Rai R, Vallal DP, Reddy ML. Clinical and histopathological profile of the patient with solitary thyroid nodule in tertiary care hospital in South India. J Evol Med Dent Sci. 2017 Nov 13;6(89):6196-9. doi: 10.14260/jemds/2017/1347.

Veith FJ, Brooks JR, Grigsby WP, Selenkow HA. The nodular thyroid gland and cancer. A practical approach to the problem. N Engl J Med. 1964 Feb 27;270(9):431-6. doi: 10.1056/NEJM196402272700901, PMID 14163220.

Khairy GA. Solitary thyroid nodule: the risk of cancer and the extent of surgical therapy. East Afr Med J. 2004 Nov 17;81(9):459-62. doi: 10.4314/eamj.v81i9.9221, PMID 15626055.

Hossain MA, Sarkar MZ, Dutta UK, Karim MA, Alam MZ. Frequency of malignancy in solitary thyroid nodule and multi-nodular goitre. Bangladesh J Orl. 2014;20(2):55-9. doi: 10.3329/bjo.v20i2.22019.

Babu R, Shyamala M, Reddy SK. Malignant incidence in solitary nodule thyroid-a clinical study. IJAR. 2015;5(2).