PHYSICO-CHEMICAL EVALUATION AND HPTLC FINGER PRINT OF SIDDHA POLY HERBAL FORMULATION SWASA KUDORI MATHIRAIâ€
Keywords:
Siddha, Polyherbal formulation, Physico- chemical properties, HPTLC, Vali, Azhal, IyyamAbstract
Objective: The main objective of this research paper is to evaluate the physico-chemical properties and HPTLC finger print profile of Swasa Kudori Mathirai in the midst of various siddha polyherbal formulations.
Methods: Swasa Kudori Mathirai was prepared by the standard operative procedure. It was investigated for physico-chemical properties and HPTLC finger print profile by authenticated methods.
Results: The values of loss on Drying at 105°C / moisture content, pH were calculated as 6.52%,5.67 respectively. Total ash, Acid insoluble Ash, Water soluble ash values were found to be 9.81%, 2.24%, 7.38% respectively. Sieve analysis revealed that 24.05%, 31.60%, 34.90% retained in 300 µm,150 µm,75 µm sieves respectively. Uniformity of weight was within the acceptable range. Friability, Hardness, Distintegration Time were found to be 0.2142%, 0.5Kg/cm2, 2 minutes 45 seconds respectively. Bulk density, Tapped density, Angle of repose, Hausner 's ratio, carr index was found to be 0.50 gm/ml,0.61 gm/ml, 34.21º,18.17%, 1.22 respectively. HPTLC finger printing revealed 4,5,7,8,9,8,8,8,6,6 phytoconstituents for the extract ranging from 1-10 µl respectively.
Conclusion: The results obtained from this study will be a reference data for further research and standardization of siddha formulations in perspective days.
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