EVALUATION OF PRESCRIBING PATTERN IN ORTHOPEDICS DEPARTMENT IN A TERTIARY CARE HOSPITAL: A PROSPECTIVE OBSERVATIONAL STUDY

DWIPEN KHANIKAR; KAMAL OJAH; LAKHIMI BORAH; MITRA BHATTACHARYYA; PRAN PRATIM SAIKIA; SIDDHARTHA SHANKAR PATOWARY; DIPTIMAYEE DEVI

doi:10.22159/ijpps.2024v16i5.50590

Authors

DWIPEN KHANIKAR Department of Pharmacology, Gauhati Medical College and Hospital, Guwahati, Assam, India https://orcid.org/0000-0002-6648-1068
KAMAL OJAH Department of Pharmacology, Gauhati Medical College and Hospital, Guwahati, Assam, India https://orcid.org/0009-0003-3583-3213
LAKHIMI BORAH Department of Pharmacology, Nalbari Medical College and Hospital, Nalbari, Assam, India https://orcid.org/0009-0007-5555-4376
MITRA BHATTACHARYYA Department of Pharmacology, Nalbari Medical College and Hospital, Nalbari, Assam, India https://orcid.org/0009-0006-4377-186X
PRAN PRATIM SAIKIA Department of Pharmacology, Gauhati Medical College and Hospital, Guwahati, Assam, India https://orcid.org/0000-0001-7118-9523
SIDDHARTHA SHANKAR PATOWARY Department of Pharmacology, Gauhati Medical College and Hospital, Guwahati, Assam, India https://orcid.org/0009-0006-2095-3134
DIPTIMAYEE DEVI Department of Pharmacology, Gauhati Medical College and Hospital, Guwahati, Assam, India https://orcid.org/0000-0003-2415-826X

DOI:

https://doi.org/10.22159/ijpps.2024v16i5.50590

Keywords:

Orthopedics, Essential drug list, Generic name, Anatomical therapeutic chemical classification system, Defined daily dose, Fixed dose combinations

Abstract

Objective: To study the demographic profile and prescription pattern in Orthopedics department in a tertiary care hospital.

Methods: A prospective, observational and cross-sectional study design was adopted for this study. A total of 144 patients were enrolled and their prescriptions were analyzed for three months. The data was analyzed by using a Microsoft Excel Worksheet. The Anatomical Therapeutic Chemical classification system and defined daily dose were used to classify the prescribed drugs.

Results: Out of 144 patients enrolled, 105 (72.92%) were male and 39 (27.08%) were female. Maximum patients were between 21-40 y of age. The mean age of the patients was 35.04±18.53. The average number of drugs per prescription was 4.84. Fracture of limbs (58.33%) was the most common diagnosis. Analgesics were the most commonly prescribed drugs. Diabetes was the most common comorbidity. The percentage of drugs prescribed by generic names was 48.06, and that from the essential drug list was 47.78. The percentage of fixed-dose combinations used was 28.55.

Conclusion: Although we found that a good percentage of drugs were prescribed from essential drug list but, this practice has to be increased in future. It is also seen that average number of drugs per prescription was high and percentage of drugs prescribed by generic names was less than that by brand names. So, there is immense scope of improvement for prescribing in the hospital.

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References

Jain S, Khan YZ, Upadhyaa P, Kumar A. Assessment of prescribing pattern in a private teaching hospital in India. Int J Pharm Sci. 2013 May 06;3(3):219-22.

Shaikh U, Chandra SN, Jayasree T, Shankar J, Kotipalli R. Prescription trends in department of orthopaedics at Tertiary Care Teaching Hospital. J Chem Pharm Res. 2013;5(11):512-7.

Ahmed M, Ali N, Rahman Ur Z, Khan Md M. A study on prescribing patterns in the management of arthritis in the department of orthopaedics. Pharm Lett. 2012;4(1):5-27.

World Health Organization. Essential medicines and health products. The pursuit of responsible use of medicines: sharing and learning from country experiences. World Health Organization. How to investigate drug use in health facilities: selected drug use indicators. Available from: http://apps.who.int/medicine docs/en/d/Js2289e/3.1.html [Last accessed on 17 Mar 2024]

Aberathna A, Morrissey H, Ball P, Zawahir S. Antibiotics utilization patterns and direct cost in an emergency treatment unit in Sri Lanka. Int J Curr Pharm Sci. 2019 Oct 12;11(6):119-22. doi: 10.22159/ijcpr.2019v11i6.36358.

Fulda TR, Lyles A, Pugh MC, Christensen DB. Current status of prospective drug utilization review. J Manag Care Pharm. 2004 Sep/Oct;10(5):433-41. doi: 10.18553/jmcp.2004.10.5.433, PMID 15369426.

SA, Rao RR, Yadunath PS. Assessment of prescribing pattern among orthopedic in-patients using who prescribing indicators. Asian J Pharm Clin Res. 2018;11(12). doi: 10.22159/ajpcr.2018.v11i12.28855.

Geneva: WHO Collaborating Centre for Drug Statistics Methodology. WHO Collaborating Centre for Drug Statistics Methodology (Norway). Guidelines for ATC classification and DDD assignment; 2002a.

Geneva: WHO collaborating centre for drug statistics methodology. WHO collaborating centre for drug statistics methodology (Norway). ATC index with DDDs; 2002b.

Jain NK, Akarte A, Deshmukh PT, Kannojia P, Garud N, Akash Y. Rationality of fixed-dose combinations: an Indian scenario. Pharm Res. 2009;1:158-68.

Dhivya K, Shiva SR, Mohammed Zulkarnane A, Gautam R. Drug utilization and prescribing pattern analysis in orthopaedic outpatient department of tertiary care Hospital. Asian J Pharm Clin Res. 2021 May 5;14(6):121-4. doi: 10.22159/ajpcr.2021v14i6.41474.

World Health Organization. Guidelines for ATC classification and DDD assignment. Geneva: WHO Collaborating Centre for Drug Statistics Methodology; 2013.

Narne HM, Dilshad S, Poojitha G, Nithya MHS, Sindhuri P, Fakruddin N. Evaluation of prescribing pattern in orthopedics department in a tertiary care hospital: a prospective observational study. IJRESM. 2021 Nov;4(11):118-20.

Malhotra S, Jain S, Aggarwal A, Pandhi P, Gupta M. Pattern of prescription of non-steroidal anti-inflammatory drugs in an orthopaedic outpatient clinic of a North Indian Tertiary Care Hospital. Indian J Pharmacol. 2005 Nov 1;37(6):404-5. doi: 10.4103/0253-7613.19083.

Ingle P, Patil PH, lathi V. Study of rational prescribing and dispensing of prescriptions with non-steroidal anti-inflammatory drugs in orthopedic outpatient department. Asian J Pharm Clin Res. 2015 May 20;8(4):278-81.

Alshakka MA, Badullah WF, Alolayan SO, Mahmoud MA. Prescribing patterns of non-steroidal anti-inflammatory drugs (NSAIDs) at outpatient departments of four hospitals. Biomed Res. 2018 Oct 30;29(19):3643-7. doi: 10.4066/ biomedicalresearch.29-18-1072.

Das BP, Adhikari N, Garg M, Rauniar GP, Naga Rani MA. Utilization pattern of nonsteroidal anti-inflammatory drugs (NSAIDs) in orthopedic practice at a tertiary care hospital in eastern Nepal. J Nep Med Assoc. 2000 Jan;39:315-8.

Shankar PR, Pai R, Dubey AK, Upadhyay DK. Prescribing patterns in the orthopaedics outpatient department in a teaching hospital in Pokhara, western Nepal. Kathmandu Univ Med J (KUMJ). 2007 Jan-Mar;5(1):16-21. PMID 18603980.

Mishra R, Keshari SS. Prescription pattern of analgesics in outpatient department in a tertiary care teaching hospital in North India. Int J Basic Clin Pharmacol. 2017 Oct;6(10):ijbcp20174361. doi: 10.18203/2319-2003.ijbcp20174361.

Baghel R, Adwal SK, Singh V, Chourishi A. Prescribing pattern and drug utilization study in inpatients of the department of orthopaedics in a rural teaching hospital of Ujjain, Madhya Pradesh, India. Int J Basic Clin Pharmacol. 2018 Sep;7(9):ijbcp20183486. doi: 10.18203/2319-2003.ijbcp20183486.

Choudhury DK, Bezbaruah BK. Prescribing pattern of analgesics in orthopedic in-patient department at tertiary care hospital in Guwahati, Assam, Northeast India. Indian J Pharmacol. 2016 Jul-Aug;48(4):377-81. doi: 10.4103/0253-7613.186207, PMID 27756947.

Shehnaz SI, Arifulla M, Sreedharan J, Sam KG. Prescribing patterns in the orthopedics outpatient department in GMC Hospital, Ajman, United Arab Emirates. GMJ. 2014;3Suppl 2:S120-31.

Patil LV, Nara M. A prospective observational study of the prescription pattern of drugs used in the treatment of osteoarthritis in a tertiary care hospital. Int J Basic Clin Pharmacol. 2017 Jan;6(1):ijbcp20164757. doi: 10.18203/2319-2003.ijbcp20164757. doi: 10.18203/2319-2003.ijbcp20164757.

Lapane KL, Spooner JJ, Mucha L, Straus WL. Effect of nonsteroidal anti-inflammatory drug use on the rate of gastrointestinal hospitalizations among people living in long-term care. J Am Geriatr Soc. 2001 May;49(5):577-84. doi: 10.1046/j.1532-5415.2001.49117.x, PMID 11380750.

Rahman MS, Zinnat AB, Samad MK. Prescribing pattern of nonsteroidal anti-inflammatory drugs at outpatient departments of teaching hospital. Bangladesh J Pharmacol. 2007 Jun;2:1-6. doi: 10.3329/bjp.v2i1.493.

Shankar PR, Partha P, Nagesh S. Prescribing patterns in medical outpatients. Int J Clinical Practice. 2002;56(7):549-51. doi: 10.1111/j.1742-1241.2002.tb11317.x.

Alam K, Mishra P, Prabhu M, Shankar PR, Palaian S, Bhandari RB. A study on rational drug prescribing and dispensing in outpatients in a tertiary care teaching hospital of Western Nepal. Kathmandu Univ Med J (KUMJ). 2006 Oct;4(4):436-43. PMID 18603950.