ANTI INFLAMMATORY ACTIVITY OF ERYTHRINA VARIEGATA
Keywords:
Erythrina variegata, Anti-inflammatory, Carrageenan induced paw edema, Cotton pellet granulomaAbstract
Objective: Erythrina variegata had been widely used for its reported biological activity in indigenous system of medicine. The present investigation was carried out to find the anti-inflammatory effect of ethanolic extract of Erythrina variegata in albino rats.
Methods: The anti-inflammatory activity was evaluated using acute inflammatory model like carrageenan induced paw edema and chronic inflammatory model like cotton pellet induced granuloma respectively.
Results: The ethanolic extract in different doses (200, and 400mg/kg, p. o) exhibited dose dependent and significant antiinflammatory activity in acute and chronic model of inflammation.
Conclusion: The alcoholic extract of Erythrina variegata has anti-inflammatory activity. This activity was related to the dose and these results corroborate the potential traditional use of the plant in folk medicine.
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