• Dzulsuhaimi Daud Reproductive Biology and Toxicology Research Group Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia
  • Adriana Azahar Reproductive Biology and Toxicology Research Group Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia
  • Siti Solehah Fatinah Zainal Abidin Reproductive Biology and Toxicology Research Group Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia
  • Alene Tawang Department of Biology, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia


Cosmos caudatus, Piper sarmentosum, Sperm quality, in-vivo fertilisation


Objective: This study was conducted to determine the sperm quality and fertility of male mice supplemented with Cosmos caudatus and Piper sarmentosum aqueous extracts.

Methods: The male mice were treated with either 0.2 ml of distilled water, 500 mg/kg bwt of Cosmos caudatus or Piper sarmentosum aqueous extract for the duration of four weeks. The body weight was checked on a weekly basis. Treated male mice then were mated with proven fertile females and the numbers of implantation sites were counted. At the end of the experimental duration, treated males were sacrificed by cervical dislocation and subjected to sperm analysis.

Results: Our data revealed that Cosmos caudatus and Piper sarmentosum increased the sperm quality and fertility in male mice. In addition, we found that the body weight was not affected by Cosmos caudatus or Piper sarmentosum aqueous extract.

Conclusion: In conclusion, Cosmos caudatus and Piper sarmentosum produced a remarkable increase in male mice reproductive performance.



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How to Cite

Daud, D., A. Azahar, S. S. F. Zainal Abidin, and A. Tawang. “THE EFFECTS OF COSMOS CAUDATUS AND PIPER SARMENTOSUM AQUEOUS EXTRACTS ON MALE MICE FERTILITY”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 7, no. 12, Dec. 2015, pp. 296-8,



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