EFFICACY OF A TOOTHPASTE CONTAINING 5% POTASSIUM NITRATE IN DESENSITIZING DENTIN HYPERSENSITIVITY
Abstract
ABSTRACT
Objective: This clinical trial compared the pain reduction achieved by a 5% potassium nitrate (KNO
) desensitizing toothpaste paste versus placebo
on adult patients with tooth hypersensitivity.
3
Methods: Investigators identified adult patients with hypersensitive teeth (which are nonpathologic such as caries) after scaling. Each hypersensitive
tooth was isolated and tested with a blast of compressed cold air delivered from a three-in-one syringe. The patient was then asked to indicate a
sensitivity score using the visual analog scale (VAS) from 0 to 10. Patients received 30 seconds application of desensitizing toothpaste containing 5%
potassium nitrate (KNO
) (Group 1) and the others with placebo toothpaste (Group 2). The teeth were tested for the second time with compressed
cold air, and the patients were asked to report the VAS again. A non-parametric test was used to analyze the results following a normality test of the
VAS.
3
Results: The Primary sampling unit for analysis were tooth. A total of 78 teeth were analyzed (Group 1 = 32 teeth and Group 2 = 46 teeth). The mean
age of the patients was 29.9, and 64% of the 33 subjects were female. The median pre-treatment VAS of Groups 1 and 2 was 6 and 5, whereas the
post-treatment VAS was 0 and 4, respectively (p<0.001). The median percentage reductions in sensitivity scores of Groups 1 and 2 were 60% and
20%, respectively (p<0.001).
Conclusion: This clinical trial showed the use of the desensitizing toothpaste containing 5% potassium nitrate on hypersensitive teeth was significantly
a more effective in immediate pain reduction than using placebo toothpaste.
Keywords: Toothpaste, 5% potassium nitrate, Dentine hypersensitivity.
Downloads
References
REFERENCES
Cartwright RB. Dentinal hypersensitivity: A narrative review.
Community Dent Health 2014;31(1):15-20.
Bartold PM. Dentinal hypersensitivity: A review. Aust Dent J
;51(3):212-8.
Walters PA. Dentinal hypersensitivity: A review. J Contemp Dent Pract
;6(2):107-17.
West NX, Sanz M, Lussi A, Bartlett D, Bouchard P, Bourgeois D.
Prevalence of dentine hypersensitivity and study of associated
factors: A European population-based cross-sectional study. J Dent
;41(10):841-51.
Scaramucci T, de Almeida Anfe TE, da Silva Ferreira S, Frias AC,
Sobral MA. Investigation of the prevalence, clinical features, and risk
factors of dentin hypersensitivity in a selected Brazilian population.
Clin Oral Investig 2014;18(2):651-7.
Zhang Y, Cheng R, Cheng G, Zhang X. Prevalence of dentine
hypersensitivity in Chinese rural adults with dental fluorosis. J Oral
Rehabil 2014;41(4):289-95.
Rees JS, Jin LJ, Lam S, Kudanowska I, Vowles R. The prevalence
of dentine hypersensitivity in a hospital clinic population in Hong
Kong. J Dent 2003;31(7):453-61.
Maharani DA. Efficacy of commercially available hydroxyapatitecontaining
toothpaste
in reducing dentin hypersensitivity.
Int J Clin
Prev
Dent 2012;8(3):151-4.
Shiau HJ. Dentin hypersensitivity. J Evid Based Dent Pract 2012;12 3
Suppl:220-8.
Chu CH, Lam A, Lo EC. Dentin hypersensitivity and its management.
Gen Dent 2011;59(2):115-22.
Vieira AH, Santiago SL. Management of dentinal hypersensitivity. Gen
Dent 2009;57(2):120-6.
Brännström M. Etiology of dentin hypersensitivity. Proc Finn Dent Soc
;88 Suppl 1:7-13.
Kumari M, Naik SB, Rao NS, Martande SS, Pradeep AR. Clinical
efficacy of a herbal dentifrice on dentinal hypersensitivity: A
randomized controlled clinical trial. Aust Dent J 2013;58(4):483-90.
Holland GR, Narhi MN, Addy M, Gangarosa L, Orchardson R.
Guidelines for the design and conduct of clinical trials on dentine
hypersensitivity. J Clin Periodontol 1997;24(11):808-13.
Ware LJ, Epps CD, Herr K, Packard A. Evaluation of the revised
faces pain scale, verbal descriptor scale, numeric rating scale, and
Iowa pain thermometer in older minority adults. Pain Manag Nurs
;7(3):117 25.
Chu CH, Lo EC. Immediate post-application effect of professional
prophylaxis with 8% arginine-calcium carbonate desensitizing paste
on hypersensitive teeth. A practitioner-based clinical trial. Am J Dent
;27(1):7-11.
Sharma N, Roy S, Kakar A, Greenspan DC, Scott R. A clinical
study comparing oral formulations containing 7.5% calcium sodium
phosphosilicate (NovaMin), 5% potassium nitrate, and 0.4% stannous
fluoride for the management of dentin hypersensitivity. J Clin Dent
;21(3):88-92.
Hróbjartsson A, Gøtzsche PC. Placebo interventions for all clinical
conditions. Cochrane Database Syst Rev 2010:CD003974.
Salian S, Thakur S, Kulkarni S, LaTorre G. A randomized controlled
clinical study evaluating the efficacy of two desensitizing dentifrices. J
Clin Dent 2010;21(3):82-7.
Davies M, Paice EM, Jones SB, Leary S, Curtis AR, West NX. Efficacy
of desensitizing dentifrices to occlude dentinal tubules. Eur J Oral Sci
;119(6):497-503.
Published
How to Cite
Issue
Section
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.